<![CDATA[Chicken bones are one type of solid waste that contains a source of protein in the form of collagen. Collagen is one of the main connective tissues of animal protein and is widely used as a biomedical material, and has anti-aging. Anti-aging in cream preparations can prevent aging of the skin. This study aims to determine whether broiler bone collagen can be formulated in cream preparations which at certain concentrations can provide anti-aging and do not irritate the skin. This research uses an experimental method, using broiler chicken bone test material. The stages of this research include isolation of collagen from broiler bones, characteristics of collagen with infrared spectrophotometry, manufacture of cream of broiler bone collagen with concentrations of 1%, 1.5%, 2.5% and 3.5% and evaluation of cream and testing the effectiveness of anti-aging agents. -aging using a skin analyzer (aramo) where the results are statistically tested using the ANOVA test with SPSS 26 free trial. The results showed that broiler bone collagen can be formulated in cream anti-aging with an oil-in-water (O/W) emulsion type. Statistical test results show the probability is less than 0.05. The formulation of broiler chicken bone collagen cream with a concentration of 3.5% showed the best anti-aging by increasing moisture by 25.2%, reducing pores 22.2%, reducing blemishes 22.9% and reducing wrinkles 22.3%. Keywords : Broiler chicken, bone, collagen, anti-aging, cream]]>
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