<![CDATA[Tuberculosis (TB) is an infectious disease that remains a major public health problem in Indonesia. Treatment success is highly dependent on the patient's adherence to taking Anti-Tuberculosis Drugs (ATDs). This study aimed to determine the relationship between perceived susceptibility, severity, benefits, barriers (stigma), cues to action (healthcare workers support), and self-efficacy with adherence to taking ATDs among TB patients in Samarinda City. This study employed a cross-sectional design with a quantitative approach involving 121 TB patients from four community health centers (Puskesmas) in Samarinda. Samples were selected using multistage sampling. Data were collected through structured interviews using questionnaires and analyzed using the Chi-Square test. There was a significant relationship between perceived benefits (p = 0.012), role of healthcare workers (p = 0.000), and self-efficacy (p = 0.001) with treatment adherence. Meanwhile, perceived susceptibility (p = 0.205), perceived severity (p = 0.288), and stigma (p = 0.831) showed no significant association. Perceived benefits, support from health workers, and self-efficacy are key factors influencing TB treatment adherence. TB control programs should focus on enhancing motivation, empowering patients, and strengthening the educational role of healthcare providers.]]>
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