The Case Mix Index (CMI) is an indicator of the average complexity of inpatient cases and resource intensity in hospital financing based on INA-CBGs. This study aimed to analyze differences in inpatient CMI according to service composition, physician specialty/service line, and severity of illness (SOI) at Jampangkulon Regional General Hospital during January 2023–December 2025. An analytical observational study with a cross-sectional approach was conducted using 41,927 inpatient claim records. Descriptive analysis and non-parametric comparative tests were performed using Mann-Whitney and Kruskal-Wallis tests, followed by Bonferroni-adjusted pairwise comparisons for stratified SOI analyses. The mean CMI was 1.67 (SD 1.23), with values ranging from 0.10 to 3.84. CMI was higher in surgical services than medical services descriptively, but the difference was not significant (p=0.180). Significant differences were found across physician specialties (p<0.001), with Obgyn having the highest mean rank (182.47). Overall SOI differences were not significant (p=0.059); however, stratified analyses were significant in surgical (p=0.012) and medical services (p=0.022). These findings indicate that CMI should be interpreted together with service line, diagnosis, procedures, documentation, and coding quality.
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