Pulmonary Tuberculosis (TB) is a chronic infectious disease caused by Mycobacterium tuberculosis. Dyspnea serves as a primary clinical manifestation where patients increase respiratory effort. To alleviate dyspnea, orthopneic positioning—involving a 30-degree forward-leaning sitting position supported by pillows for 3–30 minutes—can be integrated. This study aimed to evaluate comprehensive nursing care for Mr. F. K., who presented with an ineffective breathing pattern due to dyspnea, using orthopneic positioning at the C5 Inpatient Ward of RSUP Prof. Dr. R. D. Kandou Manado. Employing a single-case study design, the research followed the nursing process across a 3x8-hour timeframe. Data were gathered through clinical interviews, physical observations, and objective measurements of respiratory rate (RR) and oxygen saturation ($\text{SpO}_2$) pre- and post-intervention. Baseline evaluation revealed a compromised state with an RR of 24 breaths per minute and an $\text{SpO}_2$ of 90%. Following systematic orthopneic positioning, physiological parameters improved significantly, achieving a regularized RR of 20 breaths per minute and an optimal $\text{SpO}_2$ stabilization of 98%. In conclusion, orthopneic positioning effectively reduces acute dyspnea in pulmonary TB patients. Clinical nursing staff are encouraged to systematically utilize this non-pharmacological strategy alongside standard operational protocols and continuous respiratory monitoring.
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