Majalah Kedokteran Nusantara The Journal Of Medical School
Vol 49, No 2 (2016): The Journal of Medical School

Kadar hs-CRP pada Pasien DM tipe-2 Dengan dan Tanpa Hipertensi

Efi Ramadhan (Departemen Patologi Klinik, Fakultas Kedokteran, Universitas Sumatera Utara, RSUP H.Adam Malik Medan)
Ozar Sanuddin (Departemen Patologi Klinik, Fakultas Kedokteran, Universitas Sumatera Utara, RSUP H.Adam Malik Medan)
Dharma Lindarto (Divisi Endokrinologi Departemen Penyakit Dalam Fakultas Kedokteran, Universitas Sumatera Utara, Rumah Sakit Umum Pusat HajiAdam Malik Medan)



Article Info

Publish Date
05 Mar 2018

Abstract

Introduction : More than 50% of patients with type-2 diabetes have hypertension. Hypertension contributes the development of cardiovascular disease. hs-CRP is an inflammation marker which is associated with cardiovascular risk. The aim of this study is to measure hs-CRP in type-2 diabetes with and without hypertension and to assess hs-CRP levels based on cardiovascular risk group.Methods : This study is an analytical observational cross-sectional study. Performed at the Department of Clinical Pathology Adam Malik Hospital, the total of type-2 DM subjects with and without hypertension is 56, with 28 in each group. Laboratory tests: complete blood count, blood sugar levels, HbA1C, SGOT, SGPT, Lipid Profile, hs-CRP.Results : There was significant differences in the average levels of hs-CRP in type-2 diabetic patients with hypertension (4.03±2.49) and without hypertension (1.98 ± 1.93), p = 0.001. In this study seen an increase in the average levels of hs-CRP is based on group risk of cardiovascular disease in patients with type 2 diabetes with and without hypertension (p= 0,001 ). In the group of type-2 diabetes with hypertension, may not find a mild risk of cardio-vascular disease. It shows the type 2 DM patients with hypertension is more at risk of cardio-vascular disease than type 2 DM without hypertension.Discussion : hs-CRP levels were higher in type-2 diabetes with hypertension and associated with the risk of cardiovascular disease. Conclusion : There are significant differences between the levels of hs-CRP type-2 diabetes with and without hypertension.Keywords :  type-2 diabetes, hypertension, hs-CRP 

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