Aktivitas Anti Jamur 2,3-dihidroksipentadekanoat dari Kayu Mahalilis (Palaquium sp.)

Renhart Jemi (Mabasiswa Progam Studi Teknologi Serat dan Komposit Sekolah Pascasarjana IPB Jl. Darmaga Kampus IPB, Bogor)
Wasrin Syafi (Departemen Basil Hutan Fakultas Kehutanan Institut Pertanian Bogor Jl, Lingkar Akademik, Kampus IPB Darmaga, Bogor 16680)
Fauzi Ferbianto' (Departemen Basil Hutan Fakultas Kehutanan Institut Pertanian Bogor Jl, Lingkar Akademik, Kampus IPB Darmaga, Bogor 16680)
Muhammad Hanafi (Pusat Penelitian Kimia. Lembaga Ilmu Pengetahuan Indonesia, Serpong KawasanPuspitek, Serpong 15314)

Jurnal Kimia Terapan Indonesia
Vol 14, No 1 (2012)

The objectives of this research were to evaluate the extractive content of hartdwood of mahalilis wood (palaquium sp.) and identification of bio-acttve compounds wood decay fungi. Mahalilis wood was macerated with MeOH and then partitioned in stages wiht the n-hexane, CHCI31 EtOAc and n-BuOH, respectively. The result of antifungal test, show the most active 14 fraction CHCl3 comparedfraction and negative controls (CCB and itraconazole). Purification of CHCl3 fraction was column chromatographedproduced five fraction (M-I-M-5). TheM2 active fraction shown inhibited the growth to Schizophyllum communeFries withIC(so) is 56ppm and Pleurotus ostreatus with IC(so)= 55 ppm. The M2 fraction of dark brownish yellow color oil, was identified by LC-MS and IH NMR, as 2,3-dihydroxypropylpentadecanoate.Key words: Palaquium sp., antifungal, Schizophyllumcommune Fries, Pleurotus ostreatus, 2,3-dihydroxypropylpentadecanote.