Objective: To understand the modalities used for male hormonal
contraception.
Methods: Literature review
Conclusion: Male contraceptive methods are still limited but hormonal
contraceptive methods are being developed. The basic
mechanism of male hormonal contraception is to inhibit spermatogenesis
by suppression of the hypothalamic-pituitary-testicular axis
function. Administration of testosterone or androgen derivative that
is given in combination with progestin or GnRH antagonist shows
that male hormonal contraceptive is reversible, effective, and acceptable
as a male contraceptive method. However, no method of male
hormonal contraceptive is ready for clinical use and marketed due
to limited studies.
[Indones J Obstet Gynecol 2015; 3-4: 239-243]
Keywords: GnRH antagonist, male hormonal contraceptive, progestin,
testosterone
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