Objective: To compare the effectiveness of rectal misoprostol administration
to the amount of blood loss in 4th stage of labor at high
risk pregnancy.
Method: We recruited all pregnant women with high risk criteria including
anemia, age 35 years old, or the number of pregnancies
4. Women would deliver appropriate to standard procedure of
normal delivery. After that, we gave 400-mcg tablet of misoprostol
rectally in treatment group. To count the amount of blood loss
during 4th stage of labor, we put the underpad.
Result: The amount of blood loss in 4th stage of labor in the treatment
group was 201.1 (SD 80.3) ml less than the control group
(285.9 (SD 93.2) ml). The result showed that the administration of
400-mcg misoprostol tablet rectally immediately after the birth of
the placenta at high risk pregnancy impacted significantly to reduce
the amount of blood loss in 4th stage of labor (p
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