<![CDATA[Background: Anursehas an important role as a caregiver for patients and helps to manage physical needs, prevent illness, and treathealthconditions.This study aimed to determine predictors of work performance among nurses at PKU Muhammadiyah Hospital, Yogyakarta.Subjects and Method: This was an analytic observational study with a cross-sectional design. The study was conducted at PKU Muhammadiyah Hospital, Yogyakarta, from April to June 2018. A sample of 203 nurses was selected for this study by simple random sampling. The dependent variable was work performance. The independent variables were motivation, skill, tenure, and motivation. The data were collected by questionnaire and analyzed by path analysis.Results: Work performance was directly improved with better skill (b=1.74; 95%CI= 1.07 to 2.41; p<0.001), longer tenure (b=0.71; 95%CI= 0.07 to 1.35; p= 0.003), and stronger motivation (b=-0.62; 95%CI= -0.07 to 1.31; p= 0.079). Work performance was indirectly affected by satisfaction. Conclusion: Work performance is directly improved with skill, tenure, motivation, and is indirectly affected by satisfaction.Keywords: work performance, tenure, motivation, skill, satisfactionCorrespondence:Heni Rusmitasari. Masters Program in Public Health, Universitas Sebelas Maret, Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: heni.rusmitasari@gmail.comJournal of Health Policy and Management (2018), 3(1): 41-46https://doi.org/10.26911/thejhpm.2018.03.01.06]]>
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