Objective: To determine the difference between serum F2-isoprostane
levels in women with preterm deliveries compared to women
in normal preterm pregnancies.
Method: Our study is a cross sectional study. During the period of
January to August 2012, we collected 72 samples in the Emergency
Department and Obstetrics and Gynecology outpatient clinic of
Sanglah hospital, Denpasar. Our sample was divided into two
groups, 36 cases of preterm deliveries at 28-37 weeks gestational
age and 36 preterm normal pregnancies at 28-37 weeks gestational
age. We collected 3 ml of blood sample from the cubital vein and
quantified the F2-isoprostane levels at the Biology Molecular Laboratory, Faculty of Medicine University of Udayana, Denpasar. Data
was analyzed using the Shapiro Wilk test and independent t-test
with significance of =0.05.
Result: The mean F2-isoprostane level for preterm deliveries and
preterm normal pregnancies were 0.315 0.292 pg/ml and
0.017 0.018 pg/ml.
Conclusion: We can conclude from this study that there is a difference
in F2-isoprostane serum level in preterm labor and normal preterm
pregnancies.
[Indones J Obstet Gynecol 2014; 4: 182-184]
Keywords: F2-Isoprostane, normal preterm pregnancy, preterm delivery
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