Formulasi Patch Ekstrak Etanol Daun Murbei (Morus Alba L.) dengan Variasi Konsentrasi Polimer Polivinil Pirolidon dan Etil Selulosa

Aisyah Fatmawaty (Fakultas Farmasi, Universitas Hasanuddin, Kampus UNHAS Tamalanrea, Makassar-Sulawesi Selatan)
Michrun Nisa (Akademi Farmasi Kebangsaan Makassar, Jln. Perintis Kemerdekaan Km 13,7 Daya Makassar, Sulawesi Selatan 90242)
Irmayani Irmayani (Sekolah Tinggi Ilmu Farmasi Makassar, Perintis Kemerdekaan Street Km 13,7 Daya, Makassar-Indonesia)
Sunarti Sunarti (Sekolah Tinggi Ilmu Farmasi Makassar, Perintis Kemerdekaan Street Km 13,7 Daya, Makassar-Indonesia)

Journal of Pharmaceutical and Medicinal Sciences
Vol 2 No 1 (2017): JPMS

Patch formulation studies have been conducted mulberry leaf extract with various concentrations of polyvinyl pirilidon and ethyl cellulose (EC) obtain a patch with good physical characteristics. Physical evaluation includes weight, thickness, and folding endurance, loss on drying and moisture uptake. The results showed that the optimum formula by solvent evaporation method is F3 (PVP : EC = 200 : 400) with average weight (0,76±0.006 g), resilience fold (> 200), thickness (0.411±0.039 cm), drying shrinkage (38.12 > 9.29 ) and absorption (29.06 > 9.79 ).