Objective: To identify the correlation between sexually transmitted
infection and cervical precancerous lesion.
Method: The study design is crossâsectional. Samples were collected
by consecutive sampling method until the minimal amount was fulfilled.
This study was conducted in the Colposcopy Outpatient Clinic
and Cytology Laboratory, Division of Specialistic Gynecology, Department
of Obstetrics and Gynecology, Dr. Cipto Mangunkusumo
Hospital (RSCM), Jakarta, from September 2008 to March 2009.
Laboratory examination for sexually transmitted infection (STI) was
performed in Department of Dermatovenereology, RSCM, Jakarta.
Patients were grouped into cases and control group. The case group
consisted of patients diagnosed with cervical intraepithelial neoplasia
(CIN) and the control group consisted of patients without CIN.
Sexually transmitted infection was identified and its relationship to
CIN was analyzed.
Result: We included 130 patients into this study, 25.38% without
CIN and 74.62% with CIN. We found that one patient can be infected
by up to five types of infection at a time. We also discovered a statistically
significant relation between CIN 1 and STI (p=0.028), CIN 2
and STI (p=0.007), and CIN 3 and STI (p=0.013).
Conclusion: Based on our study, we discovered a significant relationship
between the incidence of STI and CIN.
Keywords: cervical intraepithelial neoplasia, cervical precancerous
lesion, sexually transmitted infection
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