Objective: Determining the cystatin C serum level among normotensive,
mild preeclamptic, severe preeclamptic pregnant women
and their relationship with the severity of preeclampsia.
Method: The study was held using cross sectional design in Prof. Dr.
RD Kandou Hospital in Manado and its network hospitals. We did on
51 samples at term pregnant women, consisting of 17 samples for
each group in normotensive, mild preeclampsia, and severe
preeclampsia. The data were analyzed using SPSS version 22.0 software
through ANOVA and Kruskal Wallis statistical test.
Result: The mean cystatin C serum concentration in normotensive
pregnant women, mild preeclampsia, and severe preeclampsia were
0.82 mg/l, 1.03 mg/l, and 1.32 mg/l; respectively. The ANOVA statistical
test showed the significant association between cystatin C level
and severity of preeclampsia (p
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