<![CDATA[Objective: To compare the classic examination results of antiphospholipid
(aPS) and antiphospatidylserine (aPL) antibody profile to
establish the diagnosis from suspected antiphospholipid antibody
syndrome (APS) patient in order to state the subsequent treatment
strategies.
Method: This descriptive cross-sectional study design was conducted
at outpatient clinics of Dr. Cipto Mangunkusumo Hospital
(RSCM) from January to December 2015. The laboratory test was
held in Clinical Pathology Laboratory RSCM/Faculty of Medicine
Universitas Indonesia (FKUI) and in corporation with Prodia laboratory.
Result: All of normal patients did not have positive result in any
laboratory examination (Lupus Anti-coagulant (LA), anticardiolipin
(aCL), anti-?2 glycoprotein I (anti-?2GPI), and aPS). In patient suspected
APS, 11 (37.1%) patients had positive aCL, 7 (25.9%) patients
had positive anti-?2GPI, and 11 (37.1%) patients had positive
aPS. The most positive cross laboratory examination was between
aCL and aPS (25.9%). In this study, we found the most positive test
result was aCL and aPS (62.9%). From this study, suspected APS patient
who had negative result in classic laboratory examination, but
showing the positive result in aPS was in 5 (18.5%) patients.
Conclusion: All normal pregnant patients do not have any positive
classic examination and aPS. Meanwhile, in patients with suspected
APS, less than 20% patients show positive result of aPS with negative
result in classic laboratory examination.
Keywords: antiphospatidylserine, antiphospolipid syndrome]]>
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