JFIOnline
Vol 7, No 3 (2015)

INSTANT POWDER FORMULATION FOR ANTI ANEMIA AND OPTIMATION EXCTRACTION CONDITION OF Moringa pterigosperma Gaertn LEAVES USING MAE

Anggraeni, Yosita - ( Universitas Indonesia)
Munim, Abdul - ( Universitas Indonesia)



Article Info

Publish Date
24 Oct 2015

Abstract

Iron supplement contains ferrous sulfate is commonly used forĀ  anemia. Unfortunately, it has bad taste, can cause nausea, and made adverse effects if taken in large doses for long periods. It is necessary to find an alternative source of raw materials, including those from plants. Moringa pterigospera Gaertn leaves was selected because it contains iron and other nutritions. The purpose of this work was to make instant powder formula for anti anemia using Moringa leaves extract as an alternative for ferous suphate iron suplementation. The extraction was performed by Microwave Assisted Extraction method. Optimation of extraction condition was performed by creating some variations in solvent composition (0-70% ethanol), microwave power (450 to 900 watts) and extraction time (3 to10 min). Iron content was determinedĀ  by Atomic Absorption Spectrophotometer at wavelength of 248 nm. Instant powder formula was made in 3 concentrations of sodium CMC as suspending agent. Results of the study showed that the most optimal extraction condition which resulted the highest iron content (2.4 mg/g extracts) achieved with 900 watts microwave power, 10 min extraction time and aquademineralisata. According to 30 panelists of hedonic test, formula which used 5% w/w of sodium CMC got the highest scores. Its powder form had 2.31% of loss on drying and 7.74 g/sec of flow rate for powder form and pH of 5.78, viscosity of 15.98 cps for reconstituted form.

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Journal Info

Abbrev

jurnal

Publisher

Subject

Health Professions Medicine & Pharmacology

Description

Jurnal Farmasi Indonesia yang diterbitkan oleh Pengurus Pusat Ikatan Apoteker Indonesia. Isi website memuat seluruh jurnal yang telah diterbitkan mencakup semua aspek dalam ilmu pengetahuan dan teknologi kefarmasian antara lain farmakologi, farmakognosi, fitokimia,farmasetika, kimia farmasi, biologi ...