Jurnal Ilmu Kefarmasian Indonesia
Vol 3 No 1 (2005): JIFI

Toksisitas Akut dan Khasiat Ekstrak Som Jawa (Talinum paniculatum Gaertn) sebagai Stimulan

Yun Astuti Nugroho (Puslitbang Farmasi dan Obat Tradisonal Badan Litbangkes)
Lucie Widowati (Puslitbang Farmasi dan Obat Tradisonal Badan Litbangkes)
Pudjiastuti Pudjiastuti (Puslitbang Farmasi dan Obat Tradisonal Badan Litbangkes)
Budi Nuratmi (Puslitbang Farmasi dan Obat Tradisonal Badan Litbangkes)



Article Info

Publish Date
27 Apr 2005

Abstract

Som Jawa (Talinum paniculatum Gaertn.) is a kind of Indonesian herbs that has similarities morphologically and chemically to Chinese ginseng. Som Jawa known as Ginseng Jawa in traditional healing has been made into various forms. The famous form is made as wine. The research on acute toxicity and efficacy test of Som Jawa as stimulant have been carried out to make Som Jawa into Indonesian Ginseng. The methodology of toxicity test is according to Weil CS (1952) and the efficacy test is according to Turner (1965). The test result showed that the value of acute toxicity of Som Jawa is 32.22 (25.59-40.56) mg/10 g BW (ip mice). At the time of starting to sleep, there was a significant difference on Som Jawa 10 mg/40g BW dose administration to Heptamyl 1.56 mg/40 g BW (p=0.00). In the swimming time extract of Som Jawa 5 and 10 mg/40 g BW showed no significant differences to Heptamyl 1.56 mg/40 g BW (p>0.05) (mean=32.88 +11.6;39.77 +14.6; 32.33 – 15.9). Som Jawa (Talinum paniculatum Gaertn.) is safe based on acute toxicity test. Extract of Som Jawa could prolong the time of starting to sleep and improve fitness.

Copyrights © 2005






Journal Info

Abbrev

jifi

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Public Health

Description

Jurnal Ilmu Kefarmasian Indonesia (JIFI) mainly focuses on a current topic in Pharmaceutical Sciences are also considered for publication by the Journal. Discussions on a topic in Pharmaceutical Sciences, Clinical Sciences, and Social Behaviour Administration. Detailed scopes of articles accepted ...