Jurnal Ilmu Kefarmasian Indonesia
Vol 7 No 2 (2009): JIFI

Formulasi Gel Pengelupas Kulit Mati yang Mengandung Etil Vitamin C dalam Sistem Penghantaran Macrobead®

MARLINE ABDASSAH (UNIVERSITAS PADJADJARAN)
TAOFIK RUSDIANA (UNIVERSITAS PADJADJARAN)
ANANG SUBGHAN (UNIVERSITAS PADJADJARAN)
GUSTIN HIDAYATI (UNIVERSITAS PADJADJARAN)



Article Info

Publish Date
30 Sep 2009

Abstract

To recover good appearance of skin, dead skin cells should be removed, among others by using exfoliating agent, and to preserve the fresh skin ethyl vitamin C could be used as an antioxidant. Formulation and evaluation of skin exfoliating gel containing ethyl vitamin C in Macrobead® delivery system, using acrylates copolymer and carboxy vinyl polymer as gel bases have been carried out. The gel evaluation included physical evaluation and safety examination. The results showed that ethyl vitamin C could be trapped into Macrobead® system with good absorption inthe ratio of active content and Macrobead® of 3:4. Based on the physical evaluation of the gel formula, it was found that formula with acrylates copolymer base has altered the consistency and homogenity of gels, but not the formula with carboxy vinyl polymer base. Gels using carboxy vinyl polymer showed good physical stability for28 days of storage. The safety evaluation indicated that the preparation was safe to be used for it did not cause irritation on consumers skin. The examination showed that the preparation could exfoliate dead skin cells and thus freshen the users’ skin effectively.

Copyrights © 2009






Journal Info

Abbrev

jifi

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Public Health

Description

Jurnal Ilmu Kefarmasian Indonesia (JIFI) mainly focuses on a current topic in Pharmaceutical Sciences are also considered for publication by the Journal. Discussions on a topic in Pharmaceutical Sciences, Clinical Sciences, and Social Behaviour Administration. Detailed scopes of articles accepted ...