Jurnal Ilmu Kefarmasian Indonesia
Vol 11 No 2 (2013): JIFI

Pengembangan Getah Pepaya, Ekstrak Pepaya (Carica papaya L.) dan Ekstrak Umbi Bengkuang (Pachyrrhizus erosus (L.) Urb.) untuk Lotion Pencerah Kulit Berdasar Aktivitas Antioksidan dan Inhibisi Tirosinase

LEONARDUS BROTO SUGENG KARDONO (LEMBAGA ILMU PENGETAHUAN INDONESIA)
LIANDHAJANI LIANDHAJANI (UNIVERSITAS PANCASILA)
NINA ARTANTI (LEMBAGA ILMU PENGETAHUAN INDONESIA)
YETI MULYATI ISKANDAR (LEMBAGA ILMU PENGETAHUAN INDONESIA)
SITI MASRURAH BROTO SUTARYO (UNIVERSITAS PANCASILA)



Article Info

Publish Date
30 Sep 2013

Abstract

Whitening or skin lightening products are well known as cosmetic. In this development, papaya latex (Carica papaya L.), papaya fruit extract and yam bean tuber extracts (Pachyrrhizus erosus (L.) Urb.) were combined for skin lightening body lotion formula. Antioxidant and tyrosinase inhibitory activities were evaluated in the starting materials and the products. Antioxidant activity evaluation was conducted using DPPH free radical scavenging activity method. Tyrosinase inhibitory evaluation was performed based on tyrosinase enzymatic inhibitory reaction to tyrosine as substrate. Papaya latex showed the highest antioxidant activity (32.01%), followed by yam bean tuber extract (27.04%) and papaya extract (26.09%). The tyrosinase inhibitory activities of papaya latex, papaya fruit extract and yam bean tuber extracts were 68.42 %, 36.80% and 52.63 % respectively, as compared to that of arbutin (100%). Based on product appearance, color, odor, pH and viscosity, the product were stable for 128 weeks. The expired date calculation on its antioxidant activity, however, the product was stable for 77 weeks. It is recommended that the product should be stored in non transparent bottle at low temperature or at about 25-28oC.

Copyrights © 2013






Journal Info

Abbrev

jifi

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Public Health

Description

Jurnal Ilmu Kefarmasian Indonesia (JIFI) mainly focuses on a current topic in Pharmaceutical Sciences are also considered for publication by the Journal. Discussions on a topic in Pharmaceutical Sciences, Clinical Sciences, and Social Behaviour Administration. Detailed scopes of articles accepted ...