JCPS (Journal of Current Pharmaceutical Sciences)
Vol 2 No 1 (2018): September 2018

ANTIBACTERIA ASSAY OF PINEAPPLE PEEL (Ananas Comosus L. MERR) MOUTHWASH EXTRACT FORMULA AGAINST Staphylococcus aureus

Helfi Nofita (STIKES Muhammadiyah Pekajangan Pekalongan)
Eko Mugiyanto (STIKES Muhammadiyah Pekajangan Pekalongan)
Wulan Agustiningrum (STIKES Muhammadiyah Pekajangan Pekalongan)



Article Info

Publish Date
07 Oct 2018

Abstract

Staphylococcus Aureus is a facultative anaerobes gram-positive bacteria that cause bad breath. Pineapple skin has enzyme bromelin, tannin, chlorine, phenol, which has the suppressing effect of bacterial growth. This aim of this study is to find out and evaluate the best pineapple extract (Ananas Comosus L. Merr) mouthwash preparation formula that meets physical requirements and has the growth inhibition of Staphylococcus Aureus ATCC 25923. Antibacterial activity assay used NA media by agar diffusion method. Physical assay include organoleptic test, pH, viscosity, and cycling test in variation of concentration extract 0,78 g, 1,56 g and 3,12 g. Antibacterial assay showed inhibitories of 1,67 mm, 7,67 mm, 11,33 mm for F1, F2, and F3 respectively with significantly different at p < 0,05.The results show that the F3 has the bigest inhibition growth and meet the physical requirements..

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Journal Info

Abbrev

jcps

Publisher

Subject

Medicine & Pharmacology

Description

Journal of Current Pharmaceutical Sciences is a scholarly journal and expects to Publish articles related to the science of pharmaceutical science became the main focus of the problem at this time. This journal may publish research results as well as the results of theoretical studies and reviews. ...