Optimation of NaOH Catalyst Consentration on 1,3-Diphenyl-2-propen-1-on Synthesis Using Microwave-Assisted Organic Synthesis (MAOS) Method

Iin Narwanti (Fakultas Farmasi, Universitas Ahmad Dahlan Jl. Prof. Dr. Soepomo S.H, Janturan, Warungboto, Umbulharjo, Yogyakarta 55164)
Narendra Bagus Kusumajati (Fakultas Farmasi, Universitas Ahmad Dahlan Jl. Prof. Dr. Soepomo S.H, Janturan, Warungboto, Umbulharjo, Yogyakarta 55164)

JKPK (Jurnal Kimia dan Pendidikan Kimia)
Vol 4, No 1 (2019): JKPK ( Jurnal Kimia dan Pendidikan Kimia)

with a variation of NaOH catalyst concentration has been done. The purpose of this study was to determine the concentration of NaOH catalyst in the synthesis of 1,3-diphenyl-2-propen-1-on using MAOS method which produced optimal yield. The synthesis of 1,3-diphenyl-2-propen-1-on using benzaldehyde and acetophenone was carried out using the MAOS method with NaOH catalyst. The variation of NaOH catalyst concentration was 10%, 20%, 30%, and 40%. Microwave radiation was carried out at 140 watts for 20 seconds. The purity of the synthesized 1,3-diphenyl-2-propen-1-on was tested by melting point, TLC, and gas chromatography. The structure of the synthesized 1,3-diphenyl-2-propen-1-on was characterized by FTIR, GC-MS and NMR. The results showed that the compound 1,3-diphenyl-2-propen-1-on can be synthesized from benzaldehyde and acetophenone using MAOS method. The obtained yield at varying catalyst concentrations of 10, 20, 30 and 40% were (50.58±1.84%, (69.20±1.58)%, (84.55±1.50)% and (90.60±0.96)%, respectively. The concentration of 40% NaOH catalyst produces the most optimal yield of synthesis products.