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Universa Medicina
Published by Universitas Trisakti
ISSN : 19073062     EISSN : 24072230     DOI : -
Core Subject : Health, Science,
Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
Universa Medicina (univ.med) is a four-monthly medical journal that publishes new research findings on a wide variety of topics of importance to biomedical science and clinical practice. Universa Medicina Online contains both the current issue and an online archive that can be accessed through browsing, advanced searching, or collections by disease or topic
Arjuna Subject : -
Articles 3 Documents
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Search results for , issue " Vol 38, No 1 (2019)" : 3 Documents clear
Psychometric properties of Persian version of Beck depression inventory in coronary patients Ahmadi, Seyed Mojtaba; Masjediarani, Abbas; Bakhtiari, Maryam; Davazdahemamy, Mohamad Hasan; Mohamadian, Rasul
Universa Medicina Vol 38, No 1 (2019)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (35.297 KB) | DOI: 10.18051/UnivMed.2019.v38.33-40

Abstract

BackgroundObtaining psychometric properties regarding specific populations increases diagnostic accuracy and reduces economic health burdens. Beck depression inventory-second version (BDI-II) is useful for the screening and assessment of depression in clinical and research settings. The aim of the present study was to investigate the psychometric properties of the Persian (Farsi) version of BDI-II in patients with coronary heart disease (CHD).  MethodsA cross-sectional study was conducted on 284 patients with CHD admitted to Imam Ali Hospital in Kermanshah. They were first given a structured clinical interview (SCID-I) and then were asked to complete the Beck depression inventory-II (BDI-II), patient health questionnaire 9 (PHQ-9) and generalized anxiety disorder 7 (GAD-7). Data were analyzed by descriptive statistics, Cronbach’s á, Spearman’s correlation coefficient, exploratory factor analysis and receiver operating characteristic curve (ROC).ResultsThe internal consistency measured using Cronbach’s alpha was 0.90. The obtained correlation of BDI-II with PHQ-9 and GAD-7 was 0.74 and 0.65, respectively (p< 0.001). Factor analysis of the inventory revealed 5 factors, namely cognitive, somatic , impaired performance , negative attitude to self and ,and self punishment respectively. The cut-off point for CHD patients was 11 with sensitivity of 0.78 and specificity of 0.81 according to the Youden index and 10 with sensitivity of 0.80 and specificity of 0.77 according to the two-stage approach. The area under the curve was 0.86 (95% Confidence Interval 0.82-0.90). ConclusionThe Persian version of the BDI-II possesses the acceptable psychometric properties that can be used to screen depression in CHD patients.
Acupressure has not an analgesic effect in patients with renal colic: a randomized controlled trial Bolvardi, Ehsan; Zarmehri, Bahram; Mousavi Bazzaz, Seyed Mojtaba; Khorsand Vakilzadeh, Ali; Foroughian, Mahdi; Hoseini Faegh, Hasan; Mehramiz, Neema John
Universa Medicina Vol 38, No 1 (2019)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (752.2 KB) | DOI: 10.18051/UnivMed.2019.v38.10-16

Abstract

BackgroundEasing renal colic (RC) pain is of the most important issues in the emergency departments. This study was conducted to investigate the analgesic effects of intravenous paracetamol in comparison to acupressure and intramuscular diclofenac in patients with RC.MethodsThis randomized clinical trial was conducted on 96 eligible patients with RC, visiting the Emergency Department of Imam Reza Hospital of Mashhad, Iran. The participants were selected by consecutive non-random sampling method, and were randomized in three groups, each comprising of 32 participants. The first and second groups received 75 mg intramuscular diclofenac and 1g intravenous paracetamol, respectively. In the third group, three acupressure points were manually stimulated for six minutes. The pain score was measured by Visual Analog Scale for pain at baseline and after 10, 30, and 60 minutes. Collected information analyses by SPSS version 20 and interpreted using descriptive statistics (frequency, percentage) and inferential statistics (chi-square test).ResultsThe mean age was 31.60 ± 7.42 years (range:18-50). The two methods (diclofenac and paracetamol groups) were significantly better in pain reduction compared to acupressure after 10 minutes (p<0.001). Ninety four percent of participants in diclofenac group, 87% of paracetamol group and none of acupressure group were completely satisfied with their treatment method (p<0.001).ConclusionThis study demonstrated that acupressure did not effectively reduces renal colic pain. It seems that contrary to acupressure, intravenous paracetamol is a safe and effective analgesic medicine for patients with RC.
CD10 expression in gastric carcinoma is correlated with tumor grade and survival Jafarian, Amir Hosein; Kooshki Forooshani, Melika; Takallou, Leila; Mohamadian Roshan, Nema
Universa Medicina Vol 38, No 1 (2019)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (20.522 KB) | DOI: 10.18051/UnivMed.2019.v38.41-47

Abstract

BackgroundGastric carcinoma (GC) is the most common non-skin malignancy in Iranian men and the second leading cause of cancer-related mortality. Invasion and metastasis are considered as the major causes of cancer-related morbidity and mortality. Proteinases such as matrix metalloproteinases play an important role in tumor progression and mediating extracellular matrix remodeling. CD10 is a 90-110kd cell surface zinc-dependent metalloproteinase and there is evidence that this membrane protein may facilitate invasion and/or metastasis of tumoral cells. The objective of this study was to determine the frequency of CD10 expression in the stromal cells of GC and determine its relationship with survival and clinicopathological factors. MethodsA cross-sectional study was performed involving 50 patients with histopathologic diagnosis of GC. CD10 expression was determined by immunohistochemistry (IHC). Survival of the patients as well as the grade and stage of the tumors and demographic variables were documented. The Kaplan-Meier test was used for data analysis.ResultsStromal CD10 was detected in 46% of the GC stromal cells. No immunoreactivity was identified in the stromal cells of normal adjacent tissue. Stromal CD10 expression in gastric carcinoma did not correlate with the age and gender of the cases as well as the size and location of the tumor, and lymph node involvement but correlated with tumor stage (p=0.01), tumor grade(p=0.01) and patients’ survival (p=0.02). ConclusionStromal CD10 expression is correlated with tumor differentiation, clinical stage and survival in GC. CD10 expression could be considered as a negative prognostic factor for gastric carcinoma.

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