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Journal of Medicine and Health
Published by Universitas Kristen Maranatha
ISSN : 24425227     EISSN : -     DOI : -
Core Subject : Health, Science,
Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health
Journal of Medicine and Health (JMH) is an open access journal (OAJ), a periodic scientific publication biannually online published on February and August; using review and screening system by peer group reviewer. JMH receives original research articles which related to medicine, health, new developing therapy from traditional medicine or herbs and developing clinical therapy. JMH also receives otiginal review articles, case report, continuing medicine and health study. Articles should be written in good English or Indonesian language.
Arjuna Subject : -
Articles 11 Documents
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Search results for , issue "Vol. 2 No. 3 (2019)" : 11 Documents clear
Potential of Fucoidan From Brown Seaweeds (Sargassum sp.) as Innovation Therapy on Breast Cancer Agung B S Satyarsa
Journal of Medicine and Health Vol. 2 No. 3 (2019)
Publisher : Universitas Kristen Maranatha

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (418.66 KB) | DOI: 10.28932/jmh.v2i3.1235

Abstract

Breast cancer is a non-communicable disease and a major health problem in the world. Based on the data from WHO in 2012, the incidence of breast cancer is reported as 1.67 million cases. One cause of the highest morbidity and mortality in breast cancer is chemoresistance. Various attempts were made to solve this problem. The purpose of this review is to describe the potential of fucoidan from brown seaweeds (Sargassum sp.) as innovation therapy on breast cancer. Fucoidan as proapoptotic agents affect many target cells (multi-targets) to induce apoptosis. Fucoidan has a potential for a new treatment of breast cancer because of its potent proapoptotic and anti-metastatic properties. However, no research has yet evaluated this in clinical trial. Hence, further studies are needed to confirm the true potential of fucoidan from brown seaweeds as therapy for breast cancer. Keywords: anti-proliferative agents, pro-apoptotic agents, fucoidan, breast cancer

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