cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
-
Contact Email
-
Phone
-
Journal Mail Official
-
Editorial Address
-
Location
Kota medan,
Sumatera utara
INDONESIA
Buletin Farmatera
Published by Universitas Muhammadiyah Sumatera Utara
ISSN : 2528410X     EISSN : 2528410X     DOI : -
Core Subject : Health,
Medicine & Pharmacology
Arjuna Subject : -
Articles 11 Documents
 1   2 
Search results for , issue "Vol 10, No 2 (2025)" : 11 Documents clear
Effectiveness of Metformin in Management Latest Type 2 Diabetes Mellitus : A Literature Study Hariaji, Ilham
Buletin Farmatera Vol 10, No 2 (2025)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v10i2.26247

Abstract

Abstract: Diabetes mellitus type 2 (DMT2) is a chronic metabolic disease whose prevalence is increasing globally. Metformin remains a first-line therapy due to its effectiveness in lowering blood glucose and its good safety profile. This literature review analyzed 25 publications from the journal Scopus Q1 (2021–2025) that evaluated the effectiveness of metformin in monotherapy and combination therapy. The studies analyzed included randomized controlled clinical trials, meta-analyses, and cohort studies. Metformin showed an average HbA1c decrease of 1.0–1.5%. Combination with SGLT2 inhibitors and GLP-1 receptor agonists improves glycemic control and lowers cardiovascular risk. Anti-inflammatory and endothelial protective effects have also been reported. Metformin remains relevant as the primary therapy, but its effectiveness increases when combined with new agents and adapted to the characteristics of the patient. Metformin is effective in the management of current DMT2, especially in combination therapy and personalization approaches.

Page 2 of 2 | Total Record : 11

 1   2 

Filter by Year

2025 2025


Reset
Filter By Issues
All Issue Vol 12, No 1 (2027) Vol 11, No 3 (2026) Vol 11, No 2 (2026) Vol 11, No 1 (2026) Vol 10, No 3 (2025) Vol 10, No 2 (2025) Vol 10, No 1 (2025) Vol 9, No 3 (2024) Vol 9, No 2 (2024) Vol 8, No 2 (2023) Vol 8, No 1 (2023) Vol 7, No 3 (2022) Vol 7, No 2 (2022) Vol 7, No 1 (2022) Vol 6, No 3 (2021) Vol 6, No 2 (2021) Vol 6, No 1 (2021) Vol 5, No 3 (2020) Vol 5, No 2 (2020) Vol 5, No 1 (2020) Vol 4, No 3 (2019) Vol 4, No 2 (2019) Vol 4, No 1 (2019) Vol 3, No 3 (2018) Vol 3, No 2 (2018) Vol 3, No 1 (2018) Vol 3, No 1 (2018): Buletin Farmatera Vol 2, No 3 (2017) Vol 2, No 2 (2017) Vol 2, No 1 (2017) Vol 1, No 2 (2016) Vol 1, No 1 (2016) More Issue