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INDONESIA
Buletin Farmatera
ISSN : 2528410X     EISSN : 2528410X     DOI : -
Core Subject : Health,
Arjuna Subject : -
Articles 5 Documents
Search results for , issue "vol 12, no 2 (2027)" : 5 Documents clear
Antibacterial Effectiveness Of Bay Leaf Extract (Syzygium Polyanthum) Against Staphylococcus Aureus Using Bacteria Disc Diffusion Method Wina Rohana Puteri; Isra Thristy; Imanda Jasmine Siregar
Buletin Farmatera Vol 12, No 2 (2027)
Publisher : Universitas Muhammadiyah Sumatera Utara

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Abstract

Abstract: About 30% of Staphylococcus aureus colonizes in the human body. This bacterium is one of the microorganisms that triggers various infectious diseases, including soft tissue and skin infections, endocarditis, osteomyelitis, bacteremia, and lethal pneumonia. One alternative that can be done is to utilize active substances that kill bacteria contained in medicinal plants. One of the plants that can be used as an alternative option is bay leaf (Syzygium polyanthum). The content of flavonoids, tannins, and essential oils in bay leaves (Syzygium polyanthum) is suspected to have antibacterial activity. The purpose of this research is to evaluate the antibacterial efficacy of bay leaf (Syzygium polyanthum) extract against Staphylococcus aureus at varying concentrations to determine its potential as a natural therapeutic agent. This study uses experimental research methods The technique used to measure antibacterial activity is disc diffusion. The results showed that bay leaf extract (Syzigium polyanthum) with concentrations of 10%, 30%, and 50% produced an average clear zone diameter of 14.83 mm, 20.00 mm, and 13.50 mm, respectively. Meanwhile, the diameter of the clear zone of chloramphenicol is 20.33 mm, and in aquadest, no clear zone is obtained. Bay leaf extract with a concentration of 30% had the highest clear zone in the treatment group.
Comparison of Knowledge, Attitudes, and Vaginal Hygiene Behaviours Related to Pathological Vaginal Discharge Between Female Students of the Faculty of Law and the Faculty of Economics Rinova Dinda Amelya Lubis; Rini Syahrani Harahap
Buletin Farmatera Vol 12, No 2 (2027)
Publisher : Universitas Muhammadiyah Sumatera Utara

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Abstract: Vaginal discharge is one of the common reproductive health problems experienced by women. It refers to fluid released from the vagina other than menstrual blood. In Indonesia, approximately 75% of women have experienced vaginal discharge at least once in their lifetime. The prevalence of vaginal discharge symptoms among adolescent girls aged 15–24 years is around 31.8%. Generally, vaginal discharge is considered physiological; however, certain factors can cause it to become pathological. One of the factors associated with the occurrence of vaginal discharge is vaginal hygiene. This study aims to analyse the differences in the levels of knowledge, attitudes, and behaviours related to vaginal hygiene among female students of the Faculty of Law and the Faculty of Economics at Universitas Muhammadiyah Sumatera Utara (UMSU) in relation to the occurrence of vaginal discharge. This study used a cross-sectional research design with an accidental sampling technique. Data were collected using a questionnaire, and the Wilcoxon Matched Pairs Test was applied for data analysis. The results showed that the majority of respondents with good knowledge of vaginal hygiene were from the Faculty of Economics, totalling 57 respondents (71.3%), while respondents with poor knowledge were found in the Faculty of Law with only 1 respondent (1.3%). Respondents with the highest proportion of positive attitudes toward vaginal hygiene were from the Faculty of Law, with 73 respondents (91.3%). In terms of behaviour, good vaginal hygiene practices were most commonly found among students of the Faculty of Economics with 58 respondents (72.5%), while the lowest was found among students of the Faculty of Law with 7 respondents (8.8%). Statistical analysis showed differences in the levels of knowledge, attitudes, and behaviours regarding vaginal hygiene in relation to the occurrence of vaginal discharge among students of the Faculty of Economics and the Faculty of Law at UMSU.In conclusion, there are differences in the levels of knowledge, attitudes, and behaviours related to vaginal hygiene between students of the Faculty of Law and the Faculty of Economics concerning the occurrence of pathological vaginal discharge.
Administration of Red Mushroom Rice (Angkak) Affects the Increase in Platelet Count in Chloramphenicol-Induced Rats Luthfiah Yuliani Indra; Annisa Annisa
Buletin Farmatera Vol 12, No 2 (2027)
Publisher : Universitas Muhammadiyah Sumatera Utara

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Abstract

Abstract: Thrombocytopenia is a condition where platelet levels in the blood decrease. The isoflavone and lovastatin content in Angkak has the potential to be an additional therapy to increase the number of platelets. This study aims to determine the effect of Red Mushroom Rice Administration (Angkak) in increasing the Number of Platelets in Chloramphenicol-Induced Rats. This research is experimental research using a pretest and posttest with a control group design. The results of the paired t-test show a significance value of 0.027 0.05. This shows that between day 0 and day 12 there are significant differences in each group. The ANOVA test results show a significance value for day 12 of 0.002. The significance value shows a value 0.05. This shows that administering Angkak on day 12 has a significant effect on platelet counts. In this study, the positive control was significantly different from the other groups. This positive control group also showed the lowest average platelet count on day 0. Treatment Group I also showed significantly different results with the highest average platelet count on day 12. Conclusion: From the results of this study, it can be concluded that the administration of boiled water, increasing the doses of 2 g/KgBW, 1 g/KgBW, and 0.5 g/KgBW, had an effect in increasing the number of platelets in male rats induced by chloramphenicol.
Differences in Haemoglobin Levels Related to The Shelf Life of Packed Red Cells (PRC) on Day 1, Day 7 And Day 15 at UTD Pirngadi Medan Melisa Putri Wulandari; Fani Ade Irma
Buletin Farmatera Vol 12, No 2 (2027)
Publisher : Universitas Muhammadiyah Sumatera Utara

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Abstract: Packed red blood cells (PRC) are blood components separated from whole blood, consisting of red blood cells with most of the plasma, leukocytes, and platelets removed. Haemoglobin is the main protein in red blood cells responsible for transporting oxygen from the lungs throughout the body and carrying carbon dioxide back to the lungs for excretion. During storage, red blood cell membranes become more fragile due to oxidative stress and metabolic changes. Membrane damage can cause hemolysis, which is the rupture of red blood cells that release free haemoglobin into the storage solution. This study aims to determine the difference in HB levels with the shelf life of packed red cells (PRC) on haemoglobin levels on day 1, day 7 and day 15 at UTD Pirngadi Medan. This type of research is a prospective study; this study was conducted at various times for comparison. The total sample in this study was 75 people. Data analysis was processed using SPSS. First, a normality test was carried out; the normality test used was Kolmogorov-Smirnov. After the normality test, a homogeneity test was carried out. If the data are homogeneously/normally distributed, a One-Way ANOVA test is performed to compare. Results: There is a significant difference between haemoglobin levels on day 1, day 7, and day 15. The storage period of PRC can affect haemoglobin levels.
Giving Carrot Juice (Daucus Carota) Is Effective to Reduce Pain Levels in Primary Dysmenorrhea Fauzy Ilyas; Yenita Yenita
Buletin Farmatera Vol 12, No 2 (2027)
Publisher : Universitas Muhammadiyah Sumatera Utara

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Abstract

Abstract: Dysmenorrhea is pain that occurs during menstruation and is most common in adolescent women, resulting in many visits to gynecology clinics. Menstrual discomfort can sometimes make women unable to perform activities and is accompanied by emotional instability. In reducing pain, this study explains the effectiveness of carrot juice in reducing primary menstrual pain. This study used a true experimental method with a randomized pre-test-post-test design. The sampling technique used was purposive sampling. Data analysis was based on the severity grade of the Verbal Multidimensional Scoring System. Data normality was tested. A paired t-test was used to determine the normal distribution of data. If the distribution was not normal, a Wilcoxon test was used. The mean score before carrot juice administration was 1.48, categorized as moderate pain, while after carrot juice administration it was 0.43, categorized as mild pain. The mean dysmenorrhea pain before and after carrot juice administration was 1.05 (95% CI: 2.50-3.20) with a mean SD of 1.00. Based on the results of the t-test, α = 0.05 indicates a P-value of 0.000, meaning the paired test results are 0.05. Carrot juice is effective in reducing menstrual pain experienced by students of the UMSU Faculty of Medicine.

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