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INDONESIA
Indonesian Journal of Chemistry
ISSN : 14119420     EISSN : 24601578     DOI : -
Indonesian Journal of Chemistry is an International, peer-reviewed, open access journal that publishes original research articles, review articles, as well as short communication in all areas of chemistry including applied chemistry. The journal is accredited by The Ministry of Research, Technology and Higher Education (RISTEKDIKTI) No : 21/E/KPT/2018 (in First Rank) and indexed in Scopus since 2012. Since 2018 (Volume 18), Indonesian Journal of Chemistry publish four issues (numbers) annually (February, May, August and November).
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Articles 25 Documents
Search results for , issue "Vol 22, No 3 (2022)" : 25 Documents clear
Gamma-Irradiated Bacterial Cellulose as a Three-Dimensional Scaffold for Osteogenic Differentiation of Rat Bone Marrow Stromal Cells Farah Nurlidar; Mime Kobayashi; Ade Lestari Yunus; Rika Heryani; Muhamad Yasin Yunus; Tita Puspitasari; Darmawan Darwis
Indonesian Journal of Chemistry Vol 22, No 3 (2022)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.71823

Abstract

The effect of gamma-irradiation on bacterial cellulose (BC) was investigated in terms of improving its properties as scaffolds for tissue engineering. BC pellicles were exposed to 25, 50, and 75 kGy gamma-ray irradiation, and X-ray diffraction analyses showed that the crystallinity of the BC decreased as stronger irradiation accelerated BC’s degradation. Fourier transform infrared spectroscopy of the irradiated BC revealed the appearance of a new peak at 1724 cm–1, indicating the formation of a new carbonyl group due to the cleavage of glycosidic linkages of the BC. Rat bone marrow stromal cells seeded on the gamma-irradiated BC incubated in an osteogenic medium for 14 days produced calcium, a late marker for osteogenic differentiation, as shown by Alizarin Red S (ARS) staining. Gamma-irradiated BC with higher irradiation doses showed intense ARS staining indicating higher calcium deposition. These findings demonstrate the feasibility of using gamma-irradiated BC as a cytocompatible 3D scaffold for bone tissue regeneration.
Effect of Calcium Carbonate Content on the Mechanical and Thermal Properties of Chitosan-Coated Poly(urethane) Foams Elvi Kustiyah; Achmad Nandang Roziafanto; Majid Amrullah; Dedi Priadi; Mochamad Chalid
Indonesian Journal of Chemistry Vol 22, No 3 (2022)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.72135

Abstract

In this work, the effect of chitosan and CaCO3 coating on polyurethane (PU) foam on the mechanical and thermal properties was studied. PU-foams were soaked in a mixture of chitosan- calcium carbonate solution at different concentrations, i.e., 0.1–0.4%. The molecular behaviors due to the incorporation of chitosan/CaCO3 into the PU-foam matrix were investigated by Fourier-Transform Infrared (FTIR) spectroscopy. Field Emission Scanning Electron Microscope (FE-SEM) was utilized to study the effect of chitosan/CaCO3 coat on the pore structure of PU-foam. FTIR spectra show changes in the peak of 1446 and 1413 cm–1, which serve as evidence of molecular interaction between PU and chitosan/CaCO3. FE-SEM images show that the addition of chitosan/calcium carbonate cells was starting to close together, probably due to the increased dispersion of calcium carbonate on the entire surface of PU-foams/chitosan, which indicates that reducing the size of the cell will increase mechanical properties. From this study, it was found that PU-foam soaked in 0.4% CaCO3 had the highest tensile strength. Coating PU-foam with 0.4% CaCO3 also improved its thermal stability, indicated by an increase in its residual mass compared to neat PU-foam.
CuO, MgO, and ZrO2 Loading on HZSM5 by Deposition-precipitation: Study of Crystallinity, Specific Surface Area, and Morphology Rizky Ibnufaatih Arvianto; Anatta Wahyu Budiman; Khoirina Dwi Nugrahaningtyas
Indonesian Journal of Chemistry Vol 22, No 3 (2022)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.72255

Abstract

Bifunctional catalysts are often used in multiple reactions to synthesize certain products. The catalytic activity of bifunctional catalysts is influenced by parameters such as crystallinity, specific surface area, metal distribution, and morphology. Bifunctional catalysts are manufactured by adding metal to the support. The metal loading to the support often affects these parameters. Therefore, this research was conducted to determine the effect of CuO, MgO, and ZrO2 addition to HZSM5 on these parameters. The often-used loading method was deposition precipitation. The pH of the metal-support precursors' solution was increased to basic (pH of 8) to deposit the metal on the support. The loading effect was investigated by producing the following materials: CuO/HZSM5, CuO/ZrO2/HZSM5, CuO/MgO/HZSM5, and CuO/MgO/ZrO2/HZSM5. Each material was characterized using XRD, SAA, SEM, Mapping, EDS, and XRF. The results showed that all metal oxides could be embedded in the HZSM5. The loading of CuO, MgO, and ZrO2 to HZSM5 did not affect the crystallinity (structure) and morphology, increased the specific surface area, and was evenly distributed inside the pore of HZSM5. Further research is needed to determine the effect of crystallinity, specific surface area, and morphology on other metals and support types.
Effect of Ascorbic Acid Concentration on the Stability of Tartrate-Capped Silver Nanoparticles Indah Miftakhul Janah; Roto Roto; Dwi Siswanta
Indonesian Journal of Chemistry Vol 22, No 3 (2022)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.73196

Abstract

In this work, tartrate-capped silver nanoparticles (AgNPs) by reducing Ag+ ions into Ag0 using L-ascorbic acid and capping disodium tartrate have been prepared. The reaction was carried out at room temperature in an alkaline medium of pH 11 to obtain a rapid and one-step green synthesis method. The effect of L-ascorbic acid concentration on the synthesis preparation was studied to investigate their impact on the particle size, morphology, and stability of the AgNPs. The obtained tartrate capped AgNPs have SPR absorbance in 390–410 nm. They have a spherical shape, as confirmed by TEM. Increasing L-ascorbic acid concentrations from 25 mM to 100 and 200 mM leads to the 27, 17, and 11 nm particle size distributions. They give the zeta potential of –33.5, –20.8, and –21.3, respectively. After a week, the decreasing absorbance peaks were 0.151, 0.0105, and 0.336 a.u. The optimum L-ascorbic acid concentration was obtained at 100 mM, indicated by the smallest FWHM point. Thus, we may conclude that lower or higher levels of reducing agents resulted in low stability. Therefore, controlling L-ascorbic acid concentration is an important parameter. A sufficient concentration and an appropriate capping agent can produce good nanoparticle stability essential for further application.
Protein Markers Related to Non-halal Slaughtering Process of Rat as Mammal Animal’s Model Detected Using Mass Spectrometry Proteome Analysis Alvina Nur Aini; Claude Mona Airin; Tri Joko Raharjo
Indonesian Journal of Chemistry Vol 22, No 3 (2022)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.73656

Abstract

Meat produced from non-halal slaughter is forbidden for Moslems. The slaughter methods contribute to the physiological response of animals expressed as different proteome profile. Proteome of two meat obtained from the halal and non-halal slaughter of Wistar rats (Rattus norvegicus) as an animal model was used to search for protein markers related to the slaughter method. The analysis employed Sodium Dodecyl Sulhate Polyacrylamide Gel Electrophoresis (SDS-PAGE), and High-Resolution Mass Spectrometer (HRMS) assisted with Label-Free Quantification (LFQ) Proteome Discoverer software. The non-halal slaughter contributed to the changes in protein expression in animal meat where thirteen proteins were up-regulated and three proteins were specifically identified in the non-halal slaughter, these three proteins are NSFL1 cofactor p47, transketolase, and Von Willebrand. There are three stable peptides identified of those three proteins, SYQDPSNAQFLESIR (m/z = 1755, z = +1) part of NSFL1 cofactor p47, LGQSDPAPLQHQVDVYQK (m/z = 2023, z = +1) part of transketolase, VPLLCTNGSVVHHEVINAMQCR (m/z = 2550, z = +1) part of Von Willebrand. Two of peptides can be targeted as markers in MRM mode LC-MS/MS routine analysis to authentication-halal slaughtering meat. The proposed MRM pair ions are 1755 to 1376, 1262, 1164, and 963, 2033 to 1355, 1016, and 762.

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