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Contact Name
Raymond Pranata
Contact Email
raymond_pranata@hotmail.com
Phone
+6282112918892
Journal Mail Official
ijc@inaheart.org
Editorial Address
Editorial Office: Heart House, Jalan Katalia Raya No. 5, Kota Bambu Utara West Jakarta, 11430 - Indonesia Telephone: +62 21 5681149, Fax: +62 21 5684220 Email: ijc@inaheart.org
Location
Kota adm. jakarta barat,
Dki jakarta
INDONESIA
Indonesian Journal of Cardiology
ISSN : 28303105     EISSN : 29647304     DOI : -
Core Subject : Health,
Indonesian Journal of Cardiology (IJC) is a peer-reviewed and open-access journal established by Indonesian Heart Association (IHA)/Perhimpunan Dokter Spesialis Kardiovaskular Indonesia (PERKI) [www.inaheart.org] on the year 1979. This journal is published to meet the needs of physicians and other health professionals for scientific articles in the cardiovascular field. All articles (research, case report, review article, and others) should be original and has never been published in any magazine/journal. Prior to publication, every manuscript will be subjected to double-blind review by peer-reviewers. We consider articles on all aspects of the cardiovascular system including clinical, translational, epidemiological, and basic studies. Subjects suitable for publication include but are not limited to the following fields: Acute Cardiovascular Care Arrhythmia / Cardiac Electrophysiology Cardiovascular Imaging Cardiovascular Pharmacotherapy Cardiovascular Public Health Policy Cardiovascular Rehabilitation Cardiovascular Research General Cardiology Heart Failure Hypertension Interventional Cardiology Pediatric Cardiology Preventive Cardiology Vascular Medicine
Articles 10 Documents
Search results for , issue "Vol. 35, No. 3 Juli - September 2014" : 10 Documents clear
Novel Bullet for Dyslipidemia and Cardiovascular Disease in the Horizon: Does Genetics Contribute to the Blueprint? Anwar Santoso
Jurnal Kardiologi Indonesia Vol. 35, No. 3 Juli - September 2014
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v35i3.423

Abstract

The development of novel therapy for dyslipidemia and cardiovascular diseases (CVD) had been constrained by some challenges, and several recent approaches have failed for lack of efficacy. Progress had been made by a single, greatest contribution from statins in reducing the risk of CVD. However, the burden of CVD and residual risk remains quite high, and new pathways to prevent and treat the diseases are still needed. Despite this clear unmet need, nevertheless many research institutions have begun to withdraw their efforts in discovering ‘the new bullet’ for this prevalent diseases1.
Asosiasi Kadar Fibrinogen dengan Indeks Resistensi Mikrovaskular pada Penderita Infark Miokard Akut dengan Elevasi Segmen ST yang menjalani Intervensi Koroner Perkutan Primer Jusup Endang; Doni Firman; Iwan Dakota
Jurnal Kardiologi Indonesia Vol. 35, No. 3 Juli - September 2014
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v35i3.424

Abstract

Background: Primary percutaneus coronary intervention (PPCI) is a first of choice to return patient’s blood flow and perfusion with ST-segment elevation myocardial infarction (STEMI), however reperfusion in macrocirculation level is not always accompanied by a sufficient microcirculation reflow due to Microvascular Obstruction (MVO). Previous study demonstrated thathigh fibrinogen concentration may affect rheological parameters of the blood and play an important role in the pathomechanism of myocardial non-reperfusion phenomenon following successful mechanical recanalisation of the infarct-related coronary artery. Another study show eda more compact, lysis-resistant fibrin network in no reflow group, but without significant relation to fibrinogen level. However, there is a lack of data regarding fibrinogen and MVO. The aim of this study is to evaluate association between fibrinogen and MVO by index of microcirculatory resistance (IMR).Methods. 55 STEMI patients undergoing primary PCI were consecutively included. The fibrinogen was evaluated using clauss method and IMR was done right after PPCI to evaluate MVO.Results. From fifty-five patients included in the study, there were 87,3% men, with mean age 53,1±8.9 years old, and smoker show the biggest proportion compare with risk factor for coronary artery disease. All the patient undergo primary percutaneus coronary intervention with mean door-to-ballon time of 89.04+37.114 minute and ischemia time of 458,69+170,709 minute. Mean IMR was 55,2 + 47,454 and mean fibrinogen level was 350,8+103,19. From the scaterred plot fibrinogen prone to had a weak negative correlation with IMR and statistically non-significant(r = -0,137; p=0,319).Conclusion. There is no correlation between fibrinogen level and IMR value in STEMIpatients undergoing PPCI
An effort to find biomarker for micro-vascular obstruction in patient with myocardial infarction undergoing primary revascularization: is fibrinogen the answer? Bambang Widyantoro
Jurnal Kardiologi Indonesia Vol. 35, No. 3 Juli - September 2014
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v35i3.425

Abstract

Meski revaskularisasi telah menunjukkan manfaat besar dalam menurunkan morbiditas dan mortalitas pada pasien infark miokard akut dengan elevasi segmen ST (IMA-EST), manfaat dari intervensi koroner perkutan primer (IKPP) yang berhasil mengembalikan aliran koroner epikardial seringkali tidak optimal di tingkat mikro sirkulasi karena adanya obstruksi mikrovaskular.Obstruksi mikrovaskular (OMV) berperan penting dalam menentukan prognosis pasien paska tindakan,1, 2 dan telah dilaporkan bahwa keberadaan obstruksi mikro-vaskular berkorelasi dengan penurunan survival pasien paska IMA-EST, melalui pengaruhnya pada proses remodeling ventrikel.3, 4
Hubungan Kadar P-selectin dengan Fungsi Atrium Kiri pada Stenosis Mitral Rematik Prafithrie Avialita Shanti; Yoga Yuniadi; Nur Haryono
Jurnal Kardiologi Indonesia Vol. 35, No. 3 Juli - September 2014
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v35i3.426

Abstract

Background. Mitral stenosis (MS) prevalence remains significant in developing countries because of the prevalence of Rheumatic Heart Disease (RHD). In moderate-severe MS patients, enormous increase in turbulent region and shear stress cause vascular endothelial dysfunction, and as the consequence, it increases the risk of thromboembolic complications. P-selectin is an adhesion molecule that play a role in the inflammation process, where it is expressed rapidly in mere minutes. Left Atrial Volume Index (LAVI) is a superior parameter compared with other two-dimensional echocardiography method to assess left atrial function.Methods. This was a cross-sectional study involving 20 MS moderate-severe patients with mitral valve area (MVA) < 1.5 cm2, to whom successful Percutaneous transvenous Balloon Mitral Valvulotomy (PBMV) was performed. Samples were taken consecutively from May-October 2013 at the National Cardiovascular Center Harapan Kita, Jakarta. Blood samples of P-selectin were collected pre and post-PBMV. The result was statistically analyzed with echocardiography data of LAVI prior PBMV to describe any association between expression of P-selectin and atrial function.Result.We found no association between LAVI and P-selectin level pre and post-PBMV in MS patients. That is described in the value of pre PBMV ?=-0.103 (95% CI -0.251-0.045) with p=0.16 and post-PBMV ?= 0.009 (95% CI -0.155-0.172) with p=0.91 We then performed linear regression test with adjusted confounding variable including sex, age, and atrial fibrillation, still we found no association between LAVI and P-selectin level, with the value of pre PBMV ?= -0.154 (95% CI -0.340-0.032) p=0.09 and post PBMV ?= -0.049 (95% CI -0.250-0.152) p=0.61.Conclusion. There is no difference in P-selectin level pre and post PBMV. There is no association between poor LAVI value and expression of P-selectin pre and post PBMV in MS.
Secreted Left Atrial P-Selectin in Mitral Stenosis after PBMV: When to Measure M. Saifur Rohman
Jurnal Kardiologi Indonesia Vol. 35, No. 3 Juli - September 2014
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v35i3.428

Abstract

The glycoprotein P-selectin, a membrane component of cell storage granules, is rapidly translocated from ?-granules of platelets and the Weibel- Palade bodies of endothelial cells to the cell surface following an inflammatory process or other stimulations. P-selectin is a cell adhesion molecule of activated platelets and endothelial cells of interest because of its role in modulating interactions between blood cells and the endothelium, and also because of the possible use of its soluble form in plasma as a predictor of adverse cardiovascular events.1In endothelial cells, within minutes of its stimulation in vitro by inflammatory mediators, such as histamine, thrombin, or phorbol esters, or hypoxia, Weibel–Palade bodies are mobilized and their von Willebrand factor are degranulated. At the same time, P-selectin is also expressed at the surface as quick astwo minutes after stimulation. However, this expressionis short-lived, reaching its peak after only 10 minutes, declining back to baseline levels after 3 hours. Additional synthesis of P-selectin is brought about within 2 hours by cytokines, such as interleukin-1 (IL-1), tumor necrosis factor-? (TNF-?), and by thrombin, lipopolysaccharide or oxygen radicals. Immunofluorescence and confocal laser cytometry are usually used to measure the translocation upon this activation.1
Temuan Gambaran CT Napkin Ring Sign Pada Pasien Asimtomatik Sony Hilal Wicaksono
Jurnal Kardiologi Indonesia Vol. 35, No. 3 Juli - September 2014
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v35i3.429

Abstract

KasusSeorang laki-laki usia 56 tahun datang ke poliklinik rawat jalan untuk memeriksakan kesehatannya saat dalam keadaan tanpa keluhan atau asimtomatik. Keluhan selama ini tidak ada yang memiliki karakteristik angina atau sesak napas. Pasien memiliki riwayat penyakit jantung koroner dikeluarganya, yaitu dua orang kakak kandungnya (laki-laki) yang telah menjalani operasi jantung dan dipasang ring.Pasien pernah memeriksakan faktor risiko kardiovaskular dengan hasil terdapat peningkatan kadar kolesterol dalam darah yaitu LDL setinggi 150 mg/dL. Selain itu pasien juga dengan hipertensi grade 1 tekanan darah sistolik berkisar 140-150mmHg. Hasil EKG menunjukkan kesimpulan normal sinus ritme, tidak ditemukan kelainan pada setiap gelombang PQRST maupun setiap segmen PR dan ST.Karena gambaran EKG masih normal, dengan faktor risiko usia jenis kelamin dan riwayat keluarga serta dislipidemia, maka kami menganjurkan deteksi aterosklerosis kepada pasien dengan metode CT coronary angiography (CTCA).
Secretory Phospholipase A2 Tipe II (SPLA II) Pada Penyakit Kardiovaskuler Djanggan Sargowo
Jurnal Kardiologi Indonesia Vol. 35, No. 3 Juli - September 2014
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v35i3.430

Abstract

Inflammatory reactions contribute to the pathogenesis of cardiovascular conditions such as atherosclerosis and ischemic damage in acute myocardial infarction (AMI). Among the mediators involved in inflammation are secretory phospholipase A2 group II (sPLA2-II) enzymes. Though some cells constitutively express Spla2-II, the synthesis by cells such as hepatocytes is typical for an acute-phase reactant. Recent literature suggest multiple roles for sPLA2-II in cardiovascular disease. In this review we discuss the role of sPLA2-II in included that sPLA2-II appears to be an inportant inflammatory mediator of cardiovascular disease.
Pedoman Terapi Memakai Alat Elektronik Kardiovaskular Implan (Aleka) Perhimpunan Dokter Spesialis Kardiovaskular Indonesia 2014 Dicky A Hanafy; Yoga Yuniadi; Sunu B Raharjo; Alexander E Tondas; Adhantoro Rahadian; Muhammad Yamin; Daniel Tanubudi; Beny Hartono; Muhammad Munawar
Jurnal Kardiologi Indonesia Vol. 35, No. 3 Juli - September 2014
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v35i3.431

Abstract

PEDOMAN TERAPI MEMAKAI ALAT ELEKTRONIK KARDIOVASKULAR IMPLAN (ALEKA)Perkembangan dan kemajuan pada diagnostik dan terapi dalam tata laksana pasien dengan kelainan irama jantung merupakan dasar disusunnya pedoman terapi memakai alat elektronik kardiovaskular implan (Aleka) ini. Pedoman ini disusun oleh Perhimpunan Aritmia Indonesia - Indonesian Heart Rhythm Society (lnaHRS), sebuah kelompok kerja dari Perhimpunan Dokter Spesialis Kardiovaskular Indonesia (PERKI), berdasarkan pedoman terbaru yang dipublikasi oleh perhimpunan Eropa maupun Amerika Utara dan disesuaikan dengan keadaan lokal di Indonesia.Pedoman Aleka ini terdiri dari alat pacu jantung permanen (APJP), defibrilator kardiak implan (DKI) dan terapi resinkronisasi jantung (TRJ). Kumpulan rekomendasi ini memberi pedoman untuk penggunaan Aleka dengan tepat tetapi bukan sebagai pedoman untuk tata laksana aritmia secara umum.Bradikardia simtomatik menjadi indikasi implantasi APJP. Sebelum keputusan diambil untuk implantasi APJP, pertanyaan utama yang muncul adalah apakah simtom yang dialami pasien berhubungan dengan bradikardia, baik yang dicurigai maupun terdokumentasi. Ada kemungkinan bahwa kondisi yang terjadi bersifat sementara (akibat iskemia, efek samping obat, gangguan elektrolit, inflamasi, sepsis) dan dapat ditangani dengan pemacuan temporer serta dapat disembuhkan dengan mengobati penyebab yang mendasari. lndikasi implantasi APJP haruslah dievaluasi secara teliti dan dicari penyebab yang mendasari. lndikasi kelas I untuk implantasi APJP tidak dapat menyingkirkan pilihan tata laksana alternatif yang mungkin ada. Diagnosis banding termasuk penyebab kardiak maupun non-kardiak harus disingkirkan terlebih dahulu.Untuk terapi memakai Aleka, tidak hanya dibutuhkan pengetahuan gangguan irama jantung yang dalam namun juga pengetahuan teknik dasar. Pendekatan transvena telah mempermudah teknik bedah dan memudahkan tindakan implantasi sehingga dapat dilakukan oleh kardiolog. Hanya dengan memiliki pengertian yang mendalam mengenai keterkaitan antara fungsi dari pemacuan yang
Aplikasi Panduan ESC tentang Penyakit Arteri Koroner Stabil 2013 dan Revaskularisasi Miokard 2014: MRI Kardiak dengan Stres Adenosin dalam Diagnosis, Stratifikasi Risiko dan Strategi Penatalaksanaan Sony Hilal Wicaksono
Jurnal Kardiologi Indonesia Vol. 35, No. 3 Juli - September 2014
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v35i3.432

Abstract

Ilustrasi KasusSeorang pasien perempuan usia 55 tahun memiliki keluhan angina tipikal/khas dan didiagnosis sebagai Angina PektorisStabil (APS), dengan factor risiko diabetes mellitus tipe 2, dislipidemia, hipertensi dan perokok aktif. Hasil elektrokardiogram (EKG) pasien ini menunjukkan irama sinus dengan laju QRS 71x/menit, gambaran gelombang qR di sadapan III, selain itu dalam batas normal.Pasien kemudian menjalani uji latih Jantung dengan treadmill. Uji treadmill dihentikan pada durasi 5 menit dan 46 detik karena kejadian penurunan tekanan darah yang drastis, dari 187/103 mmHg menjadi 117/97 mmHg. Tidak tampak perubahan gambaran elektrokardiogram.Karena hasil uji latih jantung dengan treadmill yang tidak konklusif, pada pasien direncanakan dilakukan pemeriksaan MRI kardiak dengan stress adenosine untuk mendeteksi iskemia pada kunjungan selanjutnya. Sementara pasien diberikan terapi medikamentosa yang optimal untuk penyakit arteri koroner stabil.
Intermittent Wide Qrs Complex During Sinus Rhythm Yoga Yuniadi
Jurnal Kardiologi Indonesia Vol. 35, No. 3 Juli - September 2014
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v35i3.433

Abstract

Seorang pria 40 tahun datang ke poli Aritmia dengan keluhan palpitasi berulang. Pemeriksaan fisik dalam batas normal. Ekokardiografi didapatkan EF 56% dan angiografi menunjukkan arteri koroner normal. Rekaman EKG terlihat seperti gambar di bawah ini,Rekaman EKG menunjukkan gambaran bigemini yaitu selang-seling antara kompleks QRS sempit dan lebar. Perhatikan bahwa baik kompleks QRS sempit maupun lebar keduanya didahului oleh gelombang P. Yang menarik adalah (1) interval PR sangat pendek pada saat kompleks QRS lebar dan (2) interval PP kompleks QRS sempit ke QRS sempit(A) tidak merupakan dua

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