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Dian Arrisujaya
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Sains Natural: Journal of Biology and Chemistry
Published by Universitas Nusa Bangsa
ISSN : 20863446     EISSN : 2621508X     DOI : https://doi.org/10.31938/jsn
Core Subject : Science, Agriculture, Engineering,
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry
Jurnal Sains Natural is a peer-reviewed, open access journal that publishes original research articles, review articles, as well as short communication with the objectives to explore the knowledge about natural sciences. This journal incorporates not only all branches of chemistry and biology, but also sub-disciplines like Biochemistry, Polymer, Agricultural chemistry, Environmental chemistry, etc.
Arjuna Subject : Ilmu Pertanian dan Biologi (Semua) - Ilmu Pertanian dan Biologi (Lain-Lain)
Articles 5 Documents
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Search results for , issue "Vol. 6 No. 1 (2016): Sains Natural" : 5 Documents clear
ALTERNATIF METODE ANALISIS PENETAPAN KADAR ASAM MEFENAMAT DALAM PONSAMIC 500 mg TABLET SALUT SELAPUT Syahruni Syahruni; Dian Arrisujaya
JURNAL SAINS NATURAL Vol. 6 No. 1 (2016): Sains Natural
Publisher : Universitas Nusa Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (431.008 KB) | DOI: 10.31938/jsn.v6i1.249

Abstract

Alternative of analytical methods of assay mefenamic acid in posamic 500 mg film coated tabletThe level of active substance is a requirement that must be met to ensure the quality of medicinal preparations, to carry out the assay of the active drug substance required a method that has been validated. The validity of alternative methods of assay in ponsamic mefenamic acid 500 mg film coated tablet (trade name) has been performed. Mefanat acid assay method using UV spectrophotometry, so that the limited availability of tools that can be resolved HPLC. The validity of alternative methods tested by the parameters of accuracy with standard addition method and parameters accuracy. Based on the results obtained by the value of the linearity was r equal to 0,999 and the percentage difference spectrophotometric method with HPLC method (% difference) at 0,16%. The results showed an alternative method of assay in ponsamic mefenamic acid 500 mg film coated tablet (trade name) using spectrophotometric methods, qualified acceptance in accordance with ISO / IEC 17025.Keywords: Mefenamic acid, validation method, UV spectrophotometryABSTRAK Pemeriksaan kadar zat aktif merupakan persyaratan yang harus dipenuhi untuk menjamin kualitas sediaan obat, untuk melakukan penetapan kadar zat aktif obat dibutuhkan suatu metode yang telah divalidasi. Validitas metode alternatif penetapan kadar asam mefenamat dalam ponsamic 500 mg tablet salut selaput (nama dagang) telah dilakukan. Metode penentuan kadar asam mefanat menggunakan spektrofotometri UV, sehingga ketersediaan alat HPLC yang terbatas dapat teratasi. Validitas metode alternatif diuji berdasarkan parameter akurasi dengan metode penambahan baku dan parameter ketelitian. Berdasarkan hasil diperoleh nilai linearitas adalah r sebesar 0,999 dan  persentase perbedaan metode spektrofotometri dengan metode HPLC (% Difference) sebesar 0,16%. Hasil penelitian menunjukkan metode alternatif penetapan kadar asam mefenamat dalam ponsamic 500 mg tablet salut selaput (nama dagang) menggunakan metode spektrofotometri, memenuhi syarat untuk diterima sesuai ISO/IEC 17025.Kata kunci : Asam mefenamat, Validasi metode, Spektrofotometri UV
AKTIVITAS ANTIBAKTERI INFUSA DAUN LIDAH BUAYA (Aloe vera L) TERHADAP PERTUMBUHAN Staphylococcus aureus DAN Escherichia coli Yuni Widyastuti; Nia Yuliani; I.G.A. Manik Widhyastini
JURNAL SAINS NATURAL Vol. 6 No. 1 (2016): Sains Natural
Publisher : Universitas Nusa Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (537.015 KB) | DOI: 10.31938/jsn.v6i1.253

Abstract

Antibacterial Activity of Infused Aloe Vera Leaf (Aloe Vera L) on Growth Of Stapylococcus aureus and Escherichia coliDisinfectants may act as antibacterials. Aloe vera (Aloe vera L) is one of the plants that is often used by the community as a medicinal plant that has many active compounds such as lignin, saponin and anthraquinone substances that act as antibacterial. This study aims to determine the antibacterial activity of Aloe vera leaf extracted with infusa method on the growth of Staphylococcus aureus and Escherichia coli bacteria. The research method is to see the reduction / reduction of bacterial count (% reduction) after 30 second and 60 second with disc diffusion method. The results showed decrease or decrease of bacteria count (% reduction) to Escherichia coli bacteria found in aloe leaf skin infected by 28,2% after 60 seconds. While decrease or decrease of bacteria amount (% reduction) to Staphyloccocus uareus bacteria infusa mixture of meat and skin of Aloe vera leaves of 27.5% after 60 seconds. Antibacterial test of aloe vera leaf aloe (Aloe veraL) of 100% concentration by disc diffusion method did not show any inhibition zone around cultures of test bacteria.Keywords: Aloe vera, antibacterial activity, Staphylococcus aureus, and Escherichia coli, Infusa.ABSTRAKDesinfektan dapat berfungsi sebagai antibakteri. Lidah buaya (Aloe vera L) merupakan salah satu tanaman yang sering digunakan masyarakat sebagai tanaman obat yang memiliki banyak senyawa aktif seperti lignin, saponin dan antrakuinon yaitu zat yang berfungsi sebagai antibakteri. Penelitian ini bertujuan untuk mengetahui aktivitas antibakteri daun lidah buaya (Aloe vera L) yang diekstrak dengan metode infusa terhadap pertumbuhan bakteri Staphylococcus aureus dan Escherichia coli. Metode penelitian yaitu dengan melihat penurunan/pengurangan jumlah bakteri (% reduksi) setelah waktu 30 detik dan 60 detik dengan metode difusi cakram. Hasil penelitian menunjukkan penurunan atau pengurangan jumlah bakteri (% reduksi) terhadap bakteri Escherichia coli terdapat pada infusa kulit daun lidah buaya yaitu sebesar 28,2 % setelah waktu 60 detik.Sedangkan penurunan atau pengurangan jumlah bakteri (% reduksi) terhadap bakteri Staphyloccocus uareus terdapat pada infusa campuran daging dan kulit daun lidah buaya yaitu sebesar 27,5 % setelah waktu 60 detik. Uji antibakteri infusa daun lidah buaya (Aloe veraL) konsentrasi 100% dengan metode difusi cakram tidak menunjukkan adanya zona penghambatan disekitar biakan bakteri uji.Kata kunci : Lidah buaya, Aktivitas antibakteri, Staphylococcus aureus, dan   Escherichia coli,   Infusa.
PENINGKATAN KAPASITAS PRODUKSI GAS HIDROGEN (H2) DENGAN SUBSTRAT LIMBAH BIODIESEL OLEH MUTAN GANDA Enterobacter aerogenes AD-H43 DI BATCH STIRRED TANK REACTOR (BSTR) Iwan Hidayat; Mahyudin A.R.; Srikandi Srikandi
JURNAL SAINS NATURAL Vol. 6 No. 1 (2016): Sains Natural
Publisher : Universitas Nusa Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (312.907 KB) | DOI: 10.31938/jsn.v6i1.252

Abstract

Enhancement of Hydrogen Gas Production Capacity (H2) With Substrate of Biodiesel Waste By Double Multiles Enterobacter aerogenes Ad-H43 In Batch Stirred Tank Reactor (Bstr)Hydrogen is the simplest element consisting of only one proton and one electron. Almost all components inside the cell contain hydrogen atoms. Hydrogen gas (H2) consists of two binding hydrogen atoms. H2 can be producted by chemical / physics method and biological method. The production of H2 by chemical / physics method is done thermochemically and electrolyzed water, while biologically done by microorganisms through direct and indirect biofotolysis as well as light and dark fermentation. The results showed that H2 production using a double Enterobacter aerogenes AD-H43 mutant on the BSTR fermentor scale occurred an increase in H2 capacity followed by decreased production of lactic acid due to mutation with Ethyl Methane Sulfonate (EMS). On the glycerol substrate E. aerogenes AD-H43 produces H2 of 3.14 mol / mol glycerol while E. aerogenes AY-2 produces only H2 of 2.65 mol / mol glycerol, or an increase of 18% compared to E. aerogenes AY-2 whereas for production lactic acid decreased 33% while in biodiesel waste E. aerogenes AD-H43 yield H2 0.98 mol / mol glycerol and E. aerogenes AY-2 only 0.85 mol / mol glycerol or about 15% increase and in purified biodiesel waste resulting in a higher yield of H2 from biodiesel waste of 0.89 mol / mol glycerol at E. aerogenes AY-2 and 0.98 mol / mol glycerol in E. aerogenes AD-H43.Keywords: Hydrogen, Enterobacter aerogenes, BSTR fermentorABSTRAKHidrogen adalah unsur paling sederhana yang hanya terdiri dari satu proton dan satu elektron.  Hampir semua komponen di dalam sel mengandung atom hidrogen.  Gas hidrogen (H2) terdiri atas dua atom hidrogen yang berikatan.  Pembuatan H2 dapat dilakukan dengan metode kimia/fisika dan metode biologis.  Produksi H2 dengan metode kimia/fisika dilakukan secara termokimia dan elektrolisis air, sedangkan secara biologis dilakukan oleh mikroorganisme melalui biofotolisis langsung dan tidak langsung serta fermentasi terang dan gelap. Hasil penelitian menunjukkan bahwa produksi H2 menggunakan mutan ganda Enterobacter aerogenes AD-H43 pada skala fermentor BSTR terjadi peningkatan kapasitas H2 dengan diikuti penurunan produksi asam laktat akibat mutasi dengan Ethyl Methane Sulfonate (EMS). Pada substrat gliserol E. aerogenes AD-H43 memproduksi H2 sebesar 3.14 mol/mol gliserol sedangkan E. aerogenes AY-2 hanya  memproduksi H2 sebesar 2.65 mol/mol gliserol,atau mengalami kenaikan sebesar 18 % dibandingkan E. aerogenes AY-2 sedangkan untuk produksi asam laktatnya terjadi penurunan 33% sedangkan pada limbah biodiesel E. aerogenes AD- H43 menghasilkan  yield H2 0.98 mol/mol gliserol dan E. aerogenes AY-2 hanya 0.85 mol/mol gliserol atau terjadi kenaikan sekitar 15 % dan pada limbah biodiesel yang di purifikasi menghasilkan yield H2 yang lebih tinggi dari limbah biodiesel yaitu 0.89 mol/mol gliserol pada E. aerogenes AY-2 dan 0.98 mol/mol gliserol  pada E. aerogenes AD-H43. Kata Kunci: Hidrogen, Enterobacter aerogenes, fermentor BSTR
PERBANDINGAN LAJU KOROSI PADA MATERIAL STEEL PLATE COLD COIL (SPCC) YANG DILAPISI CAT DENGAN RESIN YANG BERBEDA Winda Yulliyanti; Devy Susanty; Wahyono Wahyono
JURNAL SAINS NATURAL Vol. 6 No. 1 (2016): Sains Natural
Publisher : Universitas Nusa Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (275.297 KB) | DOI: 10.31938/jsn.v6i1.251

Abstract

Comparison of Corrosion Rate on Steel Plate Cold Coil (Spcc) Material Coated With Different ResinIron corrosion is the most prominent problem because iron is widely used as a material, for example Steel Plate Cold Coil (SPCC) material or rolled steel plate that undergoes cooling process. SPCC materials are generally used for the manufacture of automobile engines, motor equipment, building construction, battery boxes, industrial machinery, and so on. The corrosion rate was determined by the salt blowing method. This method aims to calculate the corrosion rate of the material acting on an environment containing a salt solution such as NaCl. Corrosion rate testing was done on three types of paint (paint A, paint B, and C paint). Based on analysis and observation results, Coated Steel Plate Cold Coil material B coated has the smallest corrosion rate value because B paint has epoxy resin in the presence of aromatic aromatic compound ether, aromatic hydrocarbon and aliphatic alcohol.Keywords: Iron, Steel Plate Cold Coil (SPCC), corrosion, paint ABSTRAK Korosi pada besi merupakan masalah yang paling menonjol karena besi banyak digunakan secara luas sebagai material, contohnya material Steel Plate Cold Coil (SPCC) atau gulungan plat baja yang mengalami proses pendinginan. Material SPCC umumnya digunakan untuk pembuatan mesin mobil, peralatan motor, konstruksi bangunan, kotak baterai, mesin-mesin industri, dan sebagainya. Laju korosi ditentukan dengan metode sembur garam. Metode ini bertujuan untuk menghitung kecepatan korosi dari material yang bekerja pada lingkungan yang mengandung larutan garam seperti NaCl. Pengujian laju korosi dilakukan terhadap tiga jenis cat (cat A, cat B, dan cat C). Berdasarkan hasil analisis dan pengamatan, material Steel Plate Cold Coil yang dilapisi cat B memiliki nilai laju korosi terkecil karena cat B mempunyai resin epoxy dengan adanya senyawa aromatik eter, aromatik hidrokarbon dan alifatik alkohol.Kata Kunci: Besi, Steel Plate Cold Coil (SPCC), korosi, cat
PENGUJIAN PARAMETER FISIK SABUN MANDI CAIR DARI SURFAKTAN SODIUM LAURETH SULFATE (SLES) Devita Cahyaningsih; Nina Ariesta; Rizki Amelia
JURNAL SAINS NATURAL Vol. 6 No. 1 (2016): Sains Natural
Publisher : Universitas Nusa Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (337.957 KB) | DOI: 10.31938/jsn.v6i1.250

Abstract

PHYSICAL PROPERTIES OF LIQUID SHOWER SOAP CONTAINED OF SODIUM LAURETH SULFATE (SLES) SURFACTANTSoap could be produced by saponification and neutralization process. It was contained of fatty acid, KOH, glycerin, and surfactan. The properties of surfactant determined physical properties of soap as the quality parameter of soap.  The study was conducted to examine some of the physical parameters of liquid bath soap (stability test: color, aroma, viscosity, homogeneity, viscosity and pH) in accordance with applicable standards. The study was conducted using soap which was contained of SLES surfactants (Sodium Laureth Ether Sulfate). The results were pH 8.61 and viscosity 55254 cps on stability test include oven test, cycle test, room test, and sun test.Keywords: liquid shower, Sodium Laureth Ether Sulfate, soap stability ABSTRAKSabun yang merupakan salah satu kosmetik pembersih dapat dibuat melalui dua proses, yaitu saponifikasi dan netralisasi. Sabun tersusun dari berbagai bahan, seperti asam lemak, KOH, gliserin, dan surfaktan. Sifat surfaktan dalam sabun menentukan sifat fisik dari sabun yang dihasilkan dan sebagai salah satu faktor penentu mutu. Tujuan dari penelitian ini adalah untuk menguji beberapa parameter fisik sabun mandi cair (uji stabilitas: warna, aroma, kekentalan, homogenitas, viskositas dan pH) sesuai dengan standar yang berlaku, sehingga dapat dilanjutkan ke tahap pengujian berikutnya. Penelitian ini dilakukan dengan menggunakan surfaktan SLES (Sodium Laureth Ether Sulfate). Beberapa parameter fisik terukur adalah pH 8,61 dan viskositas 55254 cps pada pengujian stabilitas meliputi oven test, cycle test, room test, dan sun test.Kata Kunci: sabun cair, Sodium Laureth Ether Sulfate, stabilitas sabun

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