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INDONESIA
Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia)
ISSN : 23386401     EISSN : 23387335     DOI : -
Core Subject : Health,
The Indonesian Journal of Obstetrics and Gynecology is an official publication of the Indonesian Society of Obstetrics and Gynekology. INAJOG is published quarterly.
Arjuna Subject : -
Articles 12 Documents
Search results for , issue "Volume 8 No. 2 April 2020" : 12 Documents clear
Contraceptive Choices for Women with Intellectual Disability: Pemilihan Kontrasepsi untuk Perempuan dengan Disabilitas Intelektual Ida B. Nugraha; Dyana S. Velies
Indonesian Journal of Obstetrics and Gynecology Volume 8 No. 2 April 2020
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (51.07 KB) | DOI: 10.32771/inajog.v8i2.673

Abstract

Objective: To describe the case of contraceptive choices for women with intellectual disabilityMetode: A case reportResults: In the case of intellectual disability, we need to perform a holistic approach to the patient.Conclusion: Contraceptive method selection needs much consideration such as medical, ethical, law, and social aspect, therefore it's recommended to start giving an informed choice since antenatal care. The downside of this case is that medical practitioners often overlook the patient's degree of intellectual disability, hence, the patients' judgement, compliance, and self-treatment of complications. The result of counselling with the patient's family, they have chosen LARC method for this patient. Sterilization for eugenic reasons cannot be done because it violates law and ethics of medical practice in Indonesia.Keywords: eugenics, contraceptive, intellectual disability, sterilization. Abstrak Tujuan: Untuk menjelaskan tentang kasus pemilihan alat kontrasepsi untuk perempuan dengan disabilitas intelektualMetode: Laporan kasusKonklusi: Pemilihan alat kontrasepsi memerlukan pertimbangan berberapa aspek seperti factor medis, etika, hukum, dan sosial. Maka itu, edukasi tentang informed choice alat kontrasepsi perlu diberikan sejak mulai antenatal care. Kekurangan pada kasus ini yaitu tenaga medis tidak menilai derajat keparahan disabilitas intelektual pasien. Oleh karena itu, tenaga medis tidak dapat menilai tingkat kemampuan dalam pertimbangan, kepatuhan, dan perawatan diri sendiri terhadap komplikasi penyakit. Hasil dari konseling dengan keluarga pasien, mereka memilih metode LARC untuk pasien. Tindakan sterlisasi untuk alasan eugenik tidak dapat dilakukan, karena tindakan tersebut melanggar etika dan hokum praktik medis yang berlaku di Indonesia.Kata kunci: disabilitas intelektual, eugenik, kontrasepsi, sterilisasi.
Characteristic of Midwife’s who Refer Complex Obstetrics Cases: Karakteristik Bidan yang Merujuk kasus Kebidanan Komplek Arietta R.D. Pusponegoro; Astrid M. P. Iskandar
Indonesian Journal of Obstetrics and Gynecology Volume 8 No. 2 April 2020
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (71.046 KB) | DOI: 10.32771/inajog.v8i2.1000

Abstract

Abstract Objective: To identify reasons for referring and characteristics of midwives who practice independently and its relation with complicated cases referred to RSCM.Method: Descriptive analytic case-control. Medical records of patients referred directly to RSCM in January 2016-July 2017 were obtained, then information about midwives and obstetric cases, along with its complications, were collected. Interview and analysis of six characteristics of midwives were conducted. Characteristics analyzed were age, education, training, duration of practice, number of patients ever treated, also distance and travel time of the referral process.Results: All midwives refer due to inadequate facilities. There is a statistically significant correlation between duration of practice and number of patients, with the complicated cases referred directly to RSCM, with OR 7.036 and 6.032, respectively.Conclusion: Midwives refer due to inadequate facilities, and so patients can be treated immediately. Characteristics that affect midwives to refer complicated cases: duration of practice and number of patients. It is necessary to re-evaluate the position of midwives who practiced independently in BPJS, refresher programs, and monitoring by relevant agencies. Further research is needed with more samples and combining midwives' and patients' characteristics in referral cases. Confounding and external factors are identified first in order to do a thorough analysis.Keywords: complicated cases, midwives' characteristics, midwives who practiced independently, referral, referral system. Abstrak Tujuan: Mengetahui alasan rujuk dan karakteristik bidan yang berpraktik mandiri serta hubungannya dengan kasus komplikatif yang dirujuk ke RSCM.Metode: Deskriptif analitik kasus kontrol. Data diambil dari rekam medis pasien yang dirujuk langsung ke RSCM di bulan Januari 2016 hingga Juli 2017, kemudian informasi mengenai data bidan dan kasus obstetri beserta komplikasinya dikumpulkan. Dilakukan wawancara dan analisis enam karakteristik bidan. Karakteristik yang dianalisis yaitu usia, pendidikan, pelatihan, lama waktu berpraktik, jumlah pasien yang pernah ditangani, serta jarak dan waktu tempuh proses merujuk. Hasil: Keseluruhan bidan merujuk karena fasilitas yang tidak memadai. Terdapat hubungan yang bermakna antara waktu praktik dan jumlah pasien yang pernah ditangani, dengan kasus komplikatif yang dirujuk langsung ke RSCM, dengan nilai OR 7.036 dan 6.032.Kesimpulan: Bidan merujuk karena fasilitas tidak memadai dan agar pasien langsung ditangani. Karakteristik bidan yang mempengaruhi dalam merujuk yaitu lama waktu praktik dan jumlah pasien yang ditangani. Perlu dilakukan evaluasi ulang mengenai kedudukan bidan yang berpraktik mandiri di BPJS, program penyegaran bidan, serta monitoring oleh instansi terkait. Perlu penelitian lanjut dengan sampel lebih banyak serta menggabungkan karakteristik bidan dan pasien pada kasus-kasus rujukan. Faktor perancu dan eksternal diidentifikasi terlebih dahulu agar analisis dilakukan menyeluruh.Kata kunci: bidan yang berpraktik mandiri, karakteristik bidan, kasus komplikatif rujukan, sistem rujukan
Side Effects of Misoprostol Per Rectal for Treating Postpartum Hemorrhage in Vaginal Delivery versus Cesarean Section: What Do We Know So Far? Efek Samping Misoprostol Per Rektal untuk Pengobatan Perdarahan Pascasalin Novitasari Nasution; Hesty U. Ramadaniati; Syamsudin Syamsudin; Ajeng Normala
Indonesian Journal of Obstetrics and Gynecology Volume 8 No. 2 April 2020
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (71.425 KB) | DOI: 10.32771/inajog.v8i2.1051

Abstract

Objective: To compare the incidence and profiles of misoprostol’ side effects given per rectal for treating postpartum haemorrhage in vaginal delivery versus cesarean section.Methods: A prospective observational study involving 40 women delivered by vaginal birth (VD) and 40 by cesarean section (CS) was undertaken in a gynecology ward of a hospital in West Java. The incidence of misoprostol’s side effects was identified through patient observation and medical note review. The side effect probability was rated by the panellists of healthcare providers. Patient characteristics and side effect data were summarized descriptively. The incidence rates of misoprostol’s side effect between the two groups were compared using Z-test.Results: Thirty-four patients (85.0%) in the VD group experienced side effects, whilst all CS patients reported at least one side effect. There was no significant difference in the proportion of patients having side effects in the two groups (p=0.366). There were 135 and 164 side effects in the VD group and CS group, respectively. There was no discernible difference in side effect profile between the two groups. Gastrointestinal side effects accounted for the most frequent side effects. Regarding the side effect probability, the panellists rated all side effects in VD patients as probable. Meanwhile, around70% of side effects in CS patients were regarded as probable leaving the remaining as definite.Conclusion: High incidence of misoprostol’s side effects was documented both in VD and CS patients. The incidence rates and side effect profile between the two delivery modes were quite similar.Keywords: cesarean section, misoprostol, postpartum haemorrhage, side effect, vaginal delivery Abstrak Tujuan:Membandingkan insiden dan profil efek samping misoprostol per rektal untuk pengobatan perdarahan pascasalin pada persalinan pervaginam versus seksio sesarea.Metode: Penelitian observasional prospektif melibatkan 40 perempuan yang melahirkan melalui persalinan pervaginan (VD) versus 40 pasien melalui seksio sesarea (CS) dilakukan di bangsal ginekologi sebuah rumah sakit di Jawa Barat. Insiden efek samping misoprostol diidentifikasi melalui pengamatan pasien dan kajian rekam medis. Probabilitas efek samping dinilai oleh panel tenaga kesehatan. Karakteristik pasien dan profil efek samping dianalisis secara deskriptif. Proporsi insiden efek samping misoprostol antara dua metode persalinan dibandingkan menggunakan uji Z.Hasil :Tiga puluh empat pasien (85,0%) pasien di kelompok VD mengalami efek samping, sementara semua pasien CS melaporkan setidaknya satu efek samping. Tidak ada perbedaan yang signifikan terkait proporsi pasien yang mengalami efek samping di kedua kelompok (p=0,366). Secara keseluruhan terdapat 135 dan 164 efek samping pada kelompok VD dan CS secara berurutan. Tidak ada perbedaan yang nyata dalam profil efek samping kedua kelompok. Efek samping terkait saluran cerna merupakan efek samping yang palings sering ditemukan. Terkait probabilitas kejadian efek samping, panelis menilai semua efek samping pada kelompok VD sebagai “mungkin”. Sementara itu, sekitar 70% efek samping pada pasien CS dikategorikan “mungkin” dan selebihnya “sangat mungkin”.Kesimpulan :Insiden tinggi efek samping misoprostol ditemukan baik pada pasien VD maupun CS. Proporsi insiden dan profil efek samping cukup seragam pada dua kelompok tersebut.Kata kunci: efek samping, misoprostol, perdarahan pascasalin, persalinan pervaginam, persalinan seksio sesarea
Effects of Levonorgestrel Implants of One Rod and Two Rod on Lipid Profile, Follicle Stimulating Hormone (FSH), and Estradiol Levels in Acceptors : Efek Implan Levonorgestrel Satu Batang dan Dua Batang terhadap Profil Lipid, Kadar Follicle Stimulating Hormone (FSH), dan Estradiol pada Akseptor Santa Maria; Heriyadi Manan; Adnan Abadi; Theodorus Theodorus
Indonesian Journal of Obstetrics and Gynecology Volume 8 No. 2 April 2020
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (86.261 KB) | DOI: 10.32771/inajog.v8i2.1109

Abstract

Abstract Objective: To find out the comparison of the effect of one-rod and two-rod levonorgestrel implants on FSH, estradiol levels and increase in acceptor lipid profile after a 3-month evaluation in the Mother Hospital of Rika Amelia Palembang.Methods: This study was a phase III clinical trial, "Open" (Open Randomized Clinical Trial), carried out randomization by comparing two types of implant KB, namely levonorgestrel implants, one rod with two rods. This research was conducted at the RSAB Rika Amelia Palembang. Research time is 6 months from November 2018 - April 2019 or until the number of samples is fulfilled.Results: Based on the installation time, the average installation time using one rods LNG was 1.54 ± 0.11 minutes and the LNG for the two rods was 2.49 ± 0.26 minutes. Majority of patients having a normal blood pressure of 89.5% in one rod LNG and 68.4% in two rod LNG. The mean body mass index (BMI) of respondents using LNG implants one rod was 24.19 ± 3.93 kg / m2 and LNG for two rods was 25.09 ± 6.11 kg / m2. Based on the menstrual pattern, it was found that 84.2% of the subjects had regular menstrual patterns in the one-rod LNG group, while there were 63.2 % of subjects who have irregular menstrual patterns. From the statistical test, it was found that there were no differences in cholesterol levels (p = 0.919), HDL (p = 0.793), LDL (p = 0.851) and triglycerides (p = 0.679). There were no differences in FSH levels between respondents using one rod and two rod LNG implants (p = 0.849) and also on estradiol (p = 0.099)Conclusion: There is no difference between the use of one-rod and two-rodlevonorgestrel implants against FSH, Estradiol levels and increased lipid profile after 3 months of implant installation. The unpleasant effect in this study was the decline in HDL, but this was accompanied by a decrease in body weight, total cholesterol, LDL, HDL due to a decrease in all aspects.Keyword: estradiol, FSH, implant contraception, lenovorgestrel, lipid profile, one-rod, two-rod Abstrak Tujuan:Untuk mengetahui perbandingan efek implanlevonorgestrel satu-batang dan dua-batang pada FSH, kadar estradiol dan peningkatan profil lipid akseptor setelah evaluasi 3 bulan di Rumah Sakit Ibu Rika Amelia Palembang.Metode: Penelitian ini adalah uji klinis fase III, "Open" (Open Randomized Clinical Trial), yang dilakukan secara acak dengan membandingkan dua jenis KB implan, yaitu levonorgestrel implan, satu batang dengan dua batang. Penelitian ini dilakukan di RSAB Rika Amelia Palembang. Waktu penelitian adalah 6 bulan dari November 2018 - April 2019 atau hingga jumlah sampel terpenuhi.Hasil :Berdasarkan waktu pemasangan didapatkan rerata waktu pemasangan yang menggunakan LNG satubatangadalah 1,54±0,11 menitdanpada LNG dua batang adalah 2,49±0,26 menit. Mayoritas pasien memiliki tekanan darah yang normal 89.5% pada LNG satu batang dan 68.4% pada LNG dua batang. Rerata indeks massa tubuh (IMT) responden yang menggunakan implan LNG satu batang sebesar 24,19 ± 3,93 kg/m2 dan LNG dua batang sebesar 25,09 ± 6,11 kg/m2. Berdasarkan pola haid, didapatkan sebanyak 84,2% subjek yang memiliki pola haid teratur pada kelompok LNG satu batang, sedangkan terdapat sebanyak 63,2% subjek yang memiliki pola haid tidak teratur. Dari uji statistik didapatkan bahwa tidak terdapat perbedaan kadar kolesterol (p = 0,919), HDL (p = 0,793), LDL (p = 0,851) dan trigliserida (p = 0,679). Tidak terdapat perbedaan kadar FSH antara responden yang menggunakan implan LNG satu batang dan dua batang (p = 0,849) dan juga pada estradiol (p=0.099)Kesimpulan: Tidak terdapat perbedaan antara penggunaan implan levonorgestrel satu batang dan dua batang terhadap kadar FSH, Estradiol serta peningkatan profil lipid setelah 3 bulan pemasangan implan. Efek yang tidak menyenangkan dalam penelitian ini adalah terjaidnya penurunan HDL, namun hal ini disertai dengan penurunan berat badan, kolesterol total, LDL, HDL dikarenakan terjadi penurunan pada seluruh aspek.Kata Kunci: dua batang, estradiol, FSH, kontrasepsi implan, lenovorgestrel, profil lipid, satu batang.
Cortisol Levels in Chronic Primary Dysmenorrhoea Patients and Non-Dysmenorrhoea : A Cross- Sectional Study: Kadar Kortisol antara Pasien Dismenorea Primer Kronis: Sebuah Studi Potong Lintang Yodi Ertandri; Syahredi S. Adnani; Hafni Bachtiar
Indonesian Journal of Obstetrics and Gynecology Volume 8 No. 2 April 2020
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (61.854 KB) | DOI: 10.32771/inajog.v8i2.1128

Abstract

Objective: To investigate whether chronic primary dysmenorrhoea will significantly increase cortisol levels in the body. This study can provide an overview of the importance of handling primary dysmenorrhoea so that it does not continue to become menstrual disorders.Method: This study used a cross-sectional comparative study method with a total sample of 26 subjects with 13 subjects included in the dysmenorrhea group and 13 other subjects belonging to the non-dysmenorrhea group. The study was conducted at Department of Obstetrics and Gynecology Faculty of Medicine Universitas Andalas network primary healthcare and Dr. M. Djamil Padang Central General Hospital. Data were analyzed using computational calculation of SPSS program with bivariate test using X2 test or chi-square test with a significance degree of 0.05.Results: Twenty six subjects (13 each group) have been sampled in this study, the mean age of the dysmenorrhea group was 26.23 ± 3.92 while the mean age of the non-dysmenorrhea group was 28.62 ± 7.10. The age difference between groups was not statistically significant with a value of p = 0.30 (p> 0.05). In the comparison of cortisol levels between the two groups, it was found that the dysmenorrhea group had a higher cortisol level of 72.3077 (7.2 µg / dL) compared to the non-dysmenorrhoea group of 60.3846 (6 µg / dL). Based on the results of the bivariate analysis using the chi-square test, the value of p = 0.148 (P> 0.05) showed that there was no significant difference between the cortisol levels of the group with chronic primary dysmenorrhea compared with the non-dysmenorrhea group.Conclusion: Chronic primary dysmenorrhea can not significantly increase cortisol levels in the body.Keywords: comparative study, chronic primary dysmenorrhea, cortisol levels, non-dysmenorrhea, menstrual disorders Abstrak Tujuan :Mengetahui apakah dismenorea primer kronis akan meningkatkan kadar kortisol dalam tubuh secara signifikan. Penelitian ini dapat memberikan gambaran pentingnya penanganan dismenorea primer agar tidak berlanjut menjadi gangguan menstruasi.Metode :Penelitian ini merupakan penelitian dengan desain potong lintang studi banding dengan jumlah total sampel sebanyak 26 subjek dengan rincian 13 subjek termasuk ke dalam kelompok dismenore dan 13 subjek lainnya termasuk ke dalam kelompok non-dismenore. Penelitian dilakukan di Puskesmas jejaring PPDS Obgyn FK Unand dan RSUP Dr. M. Djamil Padang. Data dianalisis menggunakan perhitungan komputasi program SPSS dengan uji bivariat menggunakan ujiX2 atau uji chi-square dengan derajat kemaknaan 0,05. Hasil : Dari 26 subjek (masing-masing 13 subjek) yang dijadikan sampel dalam penelitian ini, didapatkan usia rerata kelompok dismenore ialah 26,23 ± 3,92 sedangkan usia rerata kelompok non-dismenore ialah 28,62 ± 7,10. Perbedaan rerata usia antar kelompok ini tidak signifikan secara statistik dengan nilai p = 0,30 (p > 0,05). Pada perbandingan kadar kortisol antar kedua kelompok, didapatkan kelompok dismenore memiliki kadar kortisol yang lebih tinggi yaitu 72,3077 (7.2 µg/dL) dibandingkan dengan kelompok non-dismenorea yaitu 60,3846 (6 µg/dL). Berdasarkan hasil analisis bivariat menggunakan uji chi-square, didapatkan nilai p = 0,148 (P > 0,05) yang menunjukkan tidak adanya perbedaan yang signifikan antara kadar kortisol kelompok dengan dismenore primer kronis dibandingkan dengan kelompok non-dismenore.Kesimpulan : Dismenore primer kronis dapat meningkatkan kadar kortisol dalam tubuh secara signifikan.Kata kunci : dismenore primer, gangguan menstruasi, kadar kortisol, kronis, tidak dismenore, studi perbandingan
Low Vitamin D Levels Increase the Risk of Early Onset Neonatal Sepsis: Kadar vitamin D yang Rendah Meningkatkan Risiko Sepsis Neonatal Awitan Dini Lisnawati Yuyun; Ali Sungkar; Rinawati Rohsiswatno; Noroyono Wibowo; Denni Hermartin; Agustin Kindi
Indonesian Journal of Obstetrics and Gynecology Volume 8 No. 2 April 2020
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (60.906 KB) | DOI: 10.32771/inajog.v8i2.1129

Abstract

Abstract Objective: To identify the association between maternal and umbilical cord vitamin D levels with suspects of early-onset of neonatal sepsis (EONS) in newborns from mothers with preterm premature rupture of membranes (PPROM).Methods: This is a retrospective cohort study conducted from January 2017 to Augusts 2018. Data was taken consecutively from medical records and previous study data at Dr. Cipto Mangunkusumo and Persahabatan Hospital, Jakarta.Results: From total of 72 infants from mothers with PPROM, 22 infants (31%) were EONS-suspected and 50 infants (69%) were not EONS-suspected. There was a significant association between maternal and umbilical cord vitamin D levels with EONS.Conclusion: There was a significant association between maternal and umbilical cord vitamin D levels with EONS.Keywords: early-onset neonatal sepsis, preterm premature rupture of membrane, vitamin D, Abstrak Tujuan: Untuk mengetahui hubungan antara kadar vitamin D maternal dan tali pusat dengan risiko tejadinya Sepsis Neonatal Awitan Dini (SNAD) pada bayi dari ibu dengan Ketuban Pecah Dini (KPD).Metode: Desain penelitian kohort retrospektif secara consecutive sampling. Data diambil dari rekam medis dan data penelitian sebelumnya di Rumah Sakit Umum Pusat Nasional (RSUPN) Dr. Cipto Mangunkusumo dan Rumah Sakit Umum Pusat (RSUP) Persahabatan, Jakarta. Hasil: Dari 72 bayi yang dilahirkan dari ibu dengan KPD, 22 bayi (31%) diantaranya diduga mengalami SNAD, sedangkan 50 bayi lainnya tidak mengalami SNAD. Terdapat hubungan yang bermakna antara kadar vitamin D maternal dan tali pusat dengan kejadian SNAD. Kesimpulan:Terdapathubungan yang bermakna antara kadar vitamin D maternal dan tali pusat dengan kejadian SNAD.Kata kunci: ketuban pecah dini, sepsis neonatal awitan dini, vitamin D
Correlation of Normal Labor and Vacuum Extraction with Postlabor Stress Urinary Incontinence : Hubungan Cara Persalinan Normal dan Vakum Ekstraksi dengan Stres Inkontinensia Urin Pascasalin Beni Gunawan; Bobby I. Utama
Indonesian Journal of Obstetrics and Gynecology Volume 8 No. 2 April 2020
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (57.353 KB) | DOI: 10.32771/inajog.v8i2.1164

Abstract

Objective: To determine the correlation between normal delivery methods and vacuum extraction with postpartum stress urinary incontinence in West Sumatra.Methods: This study used cross-sectional study design in the Obstetrics and Gynecology Department of the RSUP Dr. M. Djamil Padang, network hospital and Puskesmas in Padang City from October 2018-February 2019. The sampling technique was consecutive sampling. Urinary stress incontinence were assessed using a questionnaire for urinary incontinence diagnosis (QUID).Results: There was a correlation between normal delivery and vacuum extraction with stress urinary incontinence after delivery in the province of West Sumatra (p <0.05).Conclusion: There is a correlation between normal labour and vacuum extraction with stress urinary incontinence after delivery in the province of West Sumatra.Keywords: normal labour, stress urinary incontinence, vacuum extraction Abstrak Tujuan: Mengetahui hubungan cara persalinan normal dan vakum ekstraksi dengan stress inkontinensia urin pascasalin di Provinsi Sumatera Barat.Metode: Penelitian ini menggunakan desain potong lintang di Poliklinik Bagian Obstetri dan Ginekologi RSUP Dr. M Djamil Padang, RS jejaring dan Puskesmas di Kota Padang sejak bulan Oktober 2018-Februari 2019, Teknik pengambilan sampel dengan consecutive sampling. Penilaian stress inkontinensia urin dengan menggunakan questionnaire for urinary incontinence diagnosis (QUID).Hasil :Terdapat hubungan persalinan normal dan vakum ekstraksi dengan stress inkontinensia urin pascasalin di provinsi Sumatera Barat (p<0,05).Kesimpulan : Penelitian menyimpulkan terdapat hubungan persalinan normal dan vakumekstraksi dengan stressinkontinensia urin pascasalin di provinsi Sumatera Barat.Kata kunci: persalinan normal, stres inkontinensia urin, vakum ekstraksi
Serum Vascular Endothelial Growth Factor Levels and Uterine Fibroid Volume: Hubungan Kadar Serum Vascular Endothelial Growth Factor dengan Volume Mioma Uteri Rajuddin Rajuddin; Ronald Oscar; Tengku P. Dewi
Indonesian Journal of Obstetrics and Gynecology Volume 8 No. 2 April 2020
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (63.357 KB) | DOI: 10.32771/inajog.v8i2.1186

Abstract

Background: Tumor size is related to variations associated with molecular markers. In recent years, it has been reported that investigation of tumor volume has become very popular. Measurement of uterine fibroids volume is very important for treatment response. Objective: The aims of this study is to find the correlation of VEGF levels and uterine fibroids volume. Methods: Observational analytic study was carried out on 80 patients with uterine fibroids indicated myomectomy. Each sample was examined for VEGF levels and volume of myoma tissue post myomectomy was measured by using Archimedes' law. Correlation test using the Spearman test. Results: A total of 80 samples of patients were examined for VEGF levels and uterine fibroids volume. The median VEGF is 360 pg/mL, the median uterine fibroids volume is 325 ml. The Spearman’s test shows p values ​​(<0.01) and r (0.999). Conclusion: There is a significant correlation between VEGF levels and uterine fibroids volume. The higher the VEGF level, the greater the volume of uterine fibroids. Keywords: VEGF, uterine fibroids volume, Archimedes law *Corresponding author: Rajuddin e-mail: rajuddin@unsyiah.ac.id dan Ronald_drozz@yahoo.com
Prevalence of Appendical Metastasis in Primary Surgery of Ovarian Epithelial Cancer: Prevalensi Metastasis Apendiks Pada Bedah Primer Kanker Epitel Ovarium Laila Nuranna; Jan H. Amili; Sigit Purbadi; Nessyah Fatahan
Indonesian Journal of Obstetrics and Gynecology Volume 8 No. 2 April 2020
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (56.859 KB) | DOI: 10.32771/inajog.v8i2.1278

Abstract

Objective: To determine the prevalence of metastasis to appendix from primary surgery of ovarian epithelial cancer at National General Hospital Dr. Cipto Mangunkusumo (RSCM), Indonesia.Methods: A cross sectional study was done using ovarian epithelial cancer patient medical record whose primary ovarian cancer and appendectomy surgery were conducted on July to December 2019 at RSCM. Patients without appendix histopatology result and previous chemotherapy were excluded in this study. Consecutive method and random sampling were used in this study.Results: : A total of 80 subjects were included in this study. Subjects have average age of 48 years old. Out of all samples, 43 samples (53.8%) were defined as stage I patient, 7 subjects (8.8%) as stage II, 30 subjects (37.5%) as stage III, and none as stage IV. Appendectomy were done and eight subjects (10%) experienced metastasis to appendix. A total of 19 subjects (23.8%) had chronic appendicitis and 53 subjects (66.3%) did not have metastasis to the appendix. Among eight subjects having appendix involvement, 4 had mucinous histology, 2 serous, and 2 endometrioid. Six out of eight were diagnosed at clinical stage III and two were diagnosed at stage I.Conclusion: The prevalence of appendix metastases from primary surgery in ovarian epithelial cancer at RSCM was 10%. Based on this research, appendectomy can be considered on ovarian cancer surgeryKeywords: appendix, metastasis, ovarian cancer. Abstrak Tujuan: Mengetahui prevalensi metastasis kanker epitelial ovarium ke apendiks pada pembedahan primer kanker epitelial ovarium di Rumah Sakit Umum Pusat Nasional Dr. Cipto Mangunkusumo (RSCM), Indonesia. Metode: Penelitian ini merupakan studi potong lintang menggunakan data rekam medis pasien kanker ovarium epitelial yang menjalani pembedahan primer dan apendiktomi pada bulan Juli hingga Desember 2019 di RSCM Pasien tanpa histopatologi apendiks atau pernah dilakukan kemoterapi sebelumnya dieksklusi dari penelitian. Digunakan metode pengambilan sampel secara acak. Hasil: Didapatkan 80 subjek penelitian yang diikutsertakan dalam penelitian. Dari 80 subjek penelitian, didapatkan rerata usia 48 tahun. Sebanyak 43 subjek (53,8%) didiagnosis dengan stadium I, 7 subjek (8,8%) sebagai stadium II, 30 subjek (37,5%) stadium III. Dari 80 subjek yang menjalani apendiktomi, didapatkan 8 subjek (10%) anak sebar ke apendiks, 19 subjek (23,8 %) apendisitis kronis, 53 subjek (66,3%) tidak terdapat anak sebar. Dari 8 subjek yang terdapat anak sebar ke apendiks dengan temuan histologi 4 musinosum, 2 serosum, 2 endometroid. Sebanyak enam dari delapan subjek terdiagnosis pada stadium klinis stadium III dan dua lainnya pada stadium klinis satu. Kesimpulan: Prevalensi metastasis apendiks pada operasi primer kanker ovarium epitelial di RSCM adalah sebesar 10%. Berdasarkan hasil penelitian ini, apendektomi dapat dipertimbangkan dilakukan pada pembedahan baik stadium awal maupun stadium lanjut.Kata kunci: , apendiks , kanker ovarium, metastatis
Management of Aplastic Anemia in Pregnancy: A Case Report: Manajemen Anemia Aplastic Pada Kehamilan: Laporan Kasus Suskhan Djusad; Yoarva Malano
Indonesian Journal of Obstetrics and Gynecology Volume 8 No. 2 April 2020
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (56.387 KB) | DOI: 10.32771/inajog.v8i2.1348

Abstract

Aplastic anemia was first recognized by Ehrlich in 1888, although the pathogenesis of aplastic anemia has remained elusive. Aplastic anemia is a subtype of anemia characterized by pancytopenia and a hypocellular bone marrow which are the risk factor can be due to chemicals, drugs, infections, irradiation, leukemia, and inherited disorders. There is universal agreement that pregnancy complicated by aplastic anemia is a serious condition. The risk to the mother is mainly in the form of hemorrhage meanwhile the fetus may suffer from growth restriction and even intrauterine death. Most of the fetal complications are due to maternal anemia. We here present one cases of pregnancy complicated by aplastic anemia, which were seen within 3 months at our hospital. This high incidence is because the hospital is a top national care referral unit with good hematology and blood bank support. Keyword: aplastic anemia, pregnancy, pancytopenia Abstrak Anemia aplastik pertama kali dikenali oleh Ehrlich pada tahun 1888, walaupun patogenesis anemia aplastik masih sulit dipahami. Anemia aplastik adalah subtipe anemia yang ditandai dengan pansitopenia dan hiposeluler sumsum tulang yang merupakan faktor risiko yang dapat disebabkan oleh bahan kimia, obat-obatan, infeksi, iradiasi, leukemia, dan kelainan bawaan. Terdapat kesepakatan universal bahwa komplikasi kehamilan berupa anemia aplastik merupakan kondisi serius. Risiko kepada ibu hamil terutama dalam bentuk perdarahan sementara janin dapat mengalami hambatan dalam pertumbuhan dan bahkan kematian dalam kandungan. Sebagian besar komplikasi janin disebabkan oleh anemia pada maternal. Kami di sini menyajikan satu kasus komplikasi kehamilan berupa anemia aplastik, yang ditemukan dalam waktu 3 bulan di rumah sakit kami. Kejadian yang tinggi ini karena rumah sakit adalah unit rujukan perawatan nasional teratas dengan hematologi yang baik dan dukungan bank darah.

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