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INDONESIA
Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia)
Published by Perkumpulan Obstetri dan Ginekologi Indonesia
ISSN : 23386401     EISSN : 23387335     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health
The Indonesian Journal of Obstetrics and Gynecology is an official publication of the Indonesian Society of Obstetrics and Gynekology. INAJOG is published quarterly.
Arjuna Subject : -
Articles 18 Documents
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Search results for , issue "Volume. 34. No. 2, April 2010" : 18 Documents clear
The Changes of H2O2 Level and Glutathione/Glutathione dioxide Ratio with the Administration of N-Acetylcystein, Vitamin C, and Vitamin E towards in Vitro Eclampsia Human Umbilical Vein Endothelial Cell Model Siti Candra Windu Baktiyani
Indonesian Journal of Obstetrics and Gynecology Volume. 34. No. 2, April 2010
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To identify the optimum dosage to lower H2O2 and to increase the highest ratio of Glutathione/Glutathione dioxide in the media of eclampsia HUVEC’s model with the administration of NAC, Vitamin C, and Vitamin E. Method: We compare the concentration of H2O2 and ratio of glutathione (GSH) glutathione dioxide (GSSG) in eclampsia HUVEC’s model (as control group), and administration of three different dose of N-Acetyl Cystein (NAC), vitamin C, vitamin E and combination of them. Result: The addition of NAC, vitamin C and vitamin E to eclampsia HUVEC’s model can reduce the H2O2 level and increase GSH/GSSG ratio (p < 0.05). The optimal dose for NAC administration is 2 μM, while greater dose hamper the result. Combination of three antioxidants showed the best result compare to single antioxidant. Conclusion: The lowest level of H2O2 and the highest ratio of GSH/GSSG is achieved with the administration of the combination of NAC 2 μM, Vitamin C 100 μM and Vitamin E 100 μM. [Indones J Obstet Gynecol 2010; 34-2: 64-8] Keywords: HUVECs, eclampsia plasma, antioxidant
Objective: There were only few studies about the characteristic of vaginal pH among contraception user in Indonesia. This study aimed to determine the effect of contraception on vaginal pH among Indonesian women. Method: This study is a cross-sectional study. The target population was Indonesian women aged 15 - 50 years. The samples consisted of 492 people. Based on the method of contraception, subjects were grouped into 4 groups, subjects with combination hormonal contraceptives, progestin only Dwiana Ocviyanti
Indonesian Journal of Obstetrics and Gynecology Volume. 34. No. 2, April 2010
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: There were only few studies about the characteristic of vaginal pH among contraception user in Indonesia. This study aimed to determine the effect of contraception on vaginal pH among Indonesian women. Method: This study is a cross-sectional study. The target population was Indonesian women aged 15 - 50 years. The samples consisted of 492 people. Based on the method of contraception, subjects were grouped into 4 groups, subjects with combination hormonal contraceptives, progestin only, condoms/IUDs, and subjects with no contraception or sterile. Vaginal acidity (pH) was examined by Dip- Stick (Merck®). Result: The average age was 30.9 ± 8.27. The methods of contraception the subjects used were combination hormonal contraception (18.0%), progestin-only (29.5%), condom/IUDs (5.1%) and no contraception/sterile (47.4%). Most subjects had vaginal pH
Effect of clomiphene citrate on the quality of cervical mucus in infertile women Elizabeth Catherine Jusuf
Indonesian Journal of Obstetrics and Gynecology Volume. 34. No. 2, April 2010
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To describe the effect of clomiphene citrate on the quality of cervical mucus in infertile women. Method: This study is a non-randomized clinical trial. The study was carried out at several education hospitals in Makassar from March 2008 to April 2009. The subjects of the study were infertile women who fulfilled the inclusion criteria with intervention study. The statistical analysis was performed using Wilcoxon Sign-ed Rank Test with α 5%. Result: There were 36 cases found, and most were in the range of 26 - 30 years old (38.9%), university level education (50%), civil servant (47.2%), normal nutritionals status (55.5%), regular menstruation cycle (94.4%), marriage length 1 - 5 years (52.8%), and previously treated (61.1%). There was a significant difference of the cervical mucus quality in the infertile women before and after the administration of clomiphene citrate which tend to become worse (p = 0.012). At previously CC-treated group, it was found that after the administration of clomiphene citrate, the quality of cervical mucus tend to be worse (100%). Conclusion: The administration of clomiphene citrate tends to have declining effect on cervical-mucus quality of infertile women. [Indones J Obstet Gynecol 2010; 34-2: 73-6] Keywords: clomiphene citrate, quality of cervical mucus, infertile women
Patient’s assessment on quality of Obstetrics and Gynecology service at Dr. Cipto Mangunkusumo Hospital Erni Nurrahmi Suprihatin Priatna
Indonesian Journal of Obstetrics and Gynecology Volume. 34. No. 2, April 2010
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To evaluate patient’s assessment on service quality of Obstetrics and Gynecology at Dr. Cipto Mangunkusumo Hospital, the importance of each service quality dimension, and the relation between quality assessment and several factors. Method: The research was performed to 112 patients who were hospitalized in the Obstetrics and Gynecology ward in August 2009. We used a questionnaire which was developed from SERVQUAL instrument. This questionnaire consists of 26 questions about patient expectation and perception on the service they received. It covered 5 service quality dimensions (reliability, responsiveness, assurance, empathy, and tangibility). Patients were asked to state the answer in Likert scale from 1 to 7. The gap between perception and expectation score was then calculated. If the gap was zero or positive it means the quality was good and if negative it means the quality was not good. Result: Among 112 respondents, 82 respondents (73.2%) assess that the service quality was not good, only 26.8% considered it good. Reliability dimension had the highest expectation score followed by assurance, responsiveness, empathy, and tangibility with the proportion of 21%, 20%, 20%, 20%, and 19% respectively. The sequence of the gap from the biggest to the smallest was empathy, responsiveness, reliability, assurance, and tangibility. There was a significant relationship between patients’ educational background and assessment of service quality (p=0.036). Conclusion: Obstetrics and Gynecology Deparment’s service quality at Dr. Cipto Mangunkusumo Hospital has not fulfilled patients’ expectation. Improvements of the service quality need to be addressed on 4 factors, which are empathy, reliability, responsiveness, and assurance. [Indones J Obstet Gynecol 2010; 34-2: 77-83] Keywords: patient expectation, patient perception, Obstetrics and Gynecology service quality
Correlation between level of serum estrogen, c-telopeptide, and interleukin-6 in determining bone density in perimenopausal women Eddy Suparman
Indonesian Journal of Obstetrics and Gynecology Volume. 34. No. 2, April 2010
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To evaluate the role of estrogen as a menopausal biochemical marker to c-telopeptide (CTx) and IL-6 as a biochemical marker of mineral bone density in perimenopausal women. Method: This is an observational, cross-sectional study in perimenopausal women between 45 - 51 years old, who matched the inclusion and exclusion criteria such as no contraception was taken before, no specific disease that could affect the laboratory findings. Samples were taken from outpatients clinic of Prof Dr. R.D. Kandou hospital. The patients were gathered for blood samples collection. Blood samples were tested in laboratory. All data were collected and being processed statistically using Pearson correlation coefficient (SPSS version 16). Result: From 60 perimenopausal women (45 - 51 years old) sample, mean age was 47.98 ± 2.26 SD. Estrogen (estradiol) level: < 10 pg/ml, maximum 358 pg/ml, and mean 77.11 ± 86.2 SD. IL-6 level: minimum is 1.645 pg/ml, maximum 7.771 pg/ml, and mean 4.317 ± 2.112 SD. We found significant correlation between age and estrogen level (correlation level < 0.05) and CTx level (in level < 0.01). From regression curve, age has no significant correlation with IL-6 concentration. However, we found significant correlation between estradiol and CTx and IL-6 with respective correlation coefficient value of < 0.01. Likewise the correlation between CTx and IL- 6 showed significant statistically with the value of the correlation coefficient < 0,01. Conclusion: There is a significant correlation between estrogen, Il-6 and CTx. These variables play an important role in the occurrence of the physiological changes in the perimenopausal women. This study also showed the occurrence of a bone reabsorption process that was marked by the increase of CTx level in accordance with the increase in the age and the increase in the level of CTx together with the decline in the level of oestrogen. Therefore, prevention therapy of osteoporosis should begin in earlier age, before the further bone reabsorption take place. [Indones J Obstet Gynecol 2010; 34-2: 84-8] Keywords: c-telopeptide, bone mineral density, estrogen, interleukin- 6, perimenopause women
Comparison of administration of estradiol valerat 1 mg and 2 mg to improve squamous epithel maturation of Pap Smear preparation on postmenopausal women Ika Sri Purnamaningsih
Indonesian Journal of Obstetrics and Gynecology Volume. 34. No. 2, April 2010
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To determine the most effective dose of estradiol valerat (daily oral administration of 1 mg or 2 mg for 14 days) to improve squamous epithel maturation of Pap Smear on postmenopausal women. Method: Seventy one postmenopausal women with atrophic Pap Smear were participated in this randomized double blind clinical trial. 35 subjects received estradiol valerat 1 mg and the other 36 subjects received estradiol valerat 2 mg. After daily oral administration of estradiol valerat for 14 days, second Pap Smear were performed to evaluate epithel maturation. The side effects were also evaluated in this study. Result: There were 5 subjects whom lost to follow up due to refused to perform second Pap Smear and 1 subject was drop out due to nausea. 65 subjects were included in final analysis. Estradiol valerat 2 mg was significantly more effective than estradiol valerat 1 mg in improving epithel maturation of Pap Smear preparation on postmenopausal women. There were no complain about nausea and vaginal bleeding. Leukorhea occurred more frequently in the 2 mg group. Conclusion: Daily oral administration of 2 mg estradiol valerat was more effective than estradiol valerat 1 mg in improving squamous epithel maturation of Pap Smear on postmenopausal women with minimal side effect (leukorhea). [Indones J Obstet Gynecol 2010; 34-2: 89-91] Keywords: Pap Smear, postmenopausal women, estradiol valerat, epithel maturation of Pap Smear
Clinical appearance and vaginal cytology of atrophic vaginitis in postmenopausal women Agnes Imelda Immanuel
Indonesian Journal of Obstetrics and Gynecology Volume. 34. No. 2, April 2010
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To find out atrophic vaginitis pattern in postmenopausal women based on clinical appearance and vaginal cytology. Method: Descriptive retrospective study with hypothesis cohort to find out clinical appearance and vaginal cytology of atrophic vaginitis based on distribution of estrogen effect (maturation value/ total maturation index) in post menopausal women in outpatient clinic of tertiary hospital in Manado, North Sulawesi. Result: There were 50 subjects met the inclusion criteria. Most of them are 55 to 59 years old, with length of menopausal period 6 to 20 years, and onset of menopause in 45 to 49 years old. Cytology study showed that atrophic vaginitis present in 66% patients. Clinical symptoms are ranging from vaginal dryness (10%), vaginal discharge (6%), and dyspareunia (20%). From clinical appearance we found 44% women had atrophic vaginitis based on vaginal secretion, 42% based on macroscopic surface/integrity of vaginal epithelium, 54% based on vaginal rugae and elasticity, and 42% based on vaginal color. However, 80% of all participants showed vaginal pH more than 7 and most of them categorized as having atrophic vaginitis. Conclusion: By using clinical appearance, we found 42% to 54% of menopausal women had atrophic vaginitis, while cytology study confirmed 66% having it. [Indones J Obstet Gynecol 2010; 34-2: 92-6] Keywords: clinical appearance, cytology, menopause, atrophic vaginitis
Knowledge and attitude of pregnant woman toward umbilical-cord-blood collection Tono Djuwantono
Indonesian Journal of Obstetrics and Gynecology Volume. 34. No. 2, April 2010
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: Stem cell technology from umbilical cord blood (UCB) has developed fast as health services. UCB could be used in many kinds of disease. Private UCB bank has been operated in many places all over Indonesia. There’s a need for research to evaluate the knowledge and attitude of pregnant woman towards the act of collecting UCB. Method: This is a cross-sectional study base on question-naire given to 163 pregnant women in three private hospitals in the Bandung City from September - November 2009. The result was analyzed with Rank-spearman correlation and Kruskal-Wallis chisquare. Result: Most respondent were 20 - 29 years old pregnant women (54.6%), with educational level of strata-1 (S-1) (41.1%), with monthly income within 5 - 10 million rupiah (35.6%). This is the second pregnancy or more (42.9%), with gestational age less than 24 weeks (61.3%) and variative obstetric history (59.5%). The average level of knowledge was poor and attitude scale was uncertain (3.4). There is a significant correlation between age (p = 0.008%; CI 95%), level of education (p = 0.0001; CI 95%) and knowledge. There is a significant correlation between gestational age and attitude (p = 0.003; CI 95%). Respondent’s level of knowledge also has a significant correlation with attitude (τs = 0.421; p = 0.0001; CI 95%). Conclusion: This study described the respondent’s poor knowledge will influence their attitudes toward UCB collection, so it is necessary for disseminating more information on UCB as an effort to get better research result on UCB. [Indones J Obstet Gynecol 2010; 34-2: 97-100] Keywords: knowledge level, attitudes, collecting UCB, pregnant woman, the Bandung city

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