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Medicinus : Jurnal Kedokteran
  • Medicinus : Jurnal Kedokteran
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Published by Universitas Pelita Harapan
ISSN : 19783094     EISSN : 26226995     DOI : -
Core Subject : Health,
Medicine & Pharmacology Public Health
Medicinus: Jurnal Kedokteran is an official journal of the Faculty of Medicine, Universitas Pelita Harapan launched in the year 2007. Medicinus is a peer-reviewed and open-access journal that covers basic, translational, or clinical aspects of health and medical science. Medicinus accepts original research articles, review articles, and also interesting case reports. Medicinus: Jurnal Kedokteran is published three times a year in February, June, and October.
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Articles 10 Documents
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Search results for , issue "Vol. 14 No. 1 (2024): October" : 10 Documents clear
The Relationship of Body Mass Index with Length of Stay in Acute Appendicitis Patients Who Have Undergoing Open Appendectomy at RSUS Lippo Village Karawaci Hospital Christianto, Putra Niko Laksamana Oceano; Sudirman, Taufik
Medicinus Vol. 14 No. 1 (2024): October
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v14i1.9194

Abstract

Background : Appendicitis is an inflammation that occurs in the veriform appendix. The Indonesian Ministry of Health announced that the number of inpatients with appendicitis is the fourth most common disease in Indonesia. Open appendectomy is a procedure for treating appendicitis. Patients who have an open appendectomy procedure require hospitalization for the wound to heal. Various studies have been conducted to find a relationship between body mass index and length of stay in patients with appendicitis but have different results, besides that research on this topic is still minimal in Indonesia. Therefore, this study was conducted to analyze the relationship between body mass index and length of stay in acute appendicitis patients who had undergone open appendectomy. Methods : This study used a cross-sectional study design with a sample population of acute appendicitis patients at Lippo Village Hospital Karawaci. 182 samples were selected using a purposive sampling technique. The research sample data was taken from the patient's medical records and will be tested for analysis using SPSS 25 with the Kruskal Wallis ANOVA method. Result : From 182 research samples, it was found that the median length of stay of patients with different body mass indexes was 3 days. Based on the Kruskal Wallis ANOVA test, there was no significant elationship between gender and length of stay (p > 0.05). Conclusions : This study shows that there is no relationship between body mass index and length of stay in acute appendicitis patients who have undergone open appendectomy.
The Relationship Between Big Five Personality Traits and Academic Performance of Asian Medical Students Lauren, Stefani; Nathania, Jocelyn; Wijayanto, Rhendy; Wijaya, Ratna Sari
Medicinus Vol. 14 No. 1 (2024): October
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v14i1.9198

Abstract

Introduction : Personality traits have been shown to influence the individual’s critical thinking, learning strategies, and motivation, resulting in the overall student’s academic performance. Academic performance is an important factor among medical students to ensure their success in long-term medical education, training and work performance as medical doctors. This study aims to evaluate the relationship between personality traits and academic performance among medical students. Methods : The study was conducted among preclinical medical students from the Medical Schools of Pelita Harapan University, Indonesia. The personality traits were assessed using the NEO Five-Factor Inventory-3 (NEO-FFI-3), which consists of 60 items assessing the five personality traits (neuroticism, extraversion, openness, agreeableness, and conscientiousness). The academic performance was evaluated using the cumulative grade point average (CGPA) score. Results : A total of 224 participants were included in this study. The mean age of the participants was 19.8 years old (SD±1.3). Neuroticism was the predominant personality trait among medical students and was found to be negatively associated with CGPA in univariable and multivariable analyses (p<0.05). Conclusion : This study reveals that neuroticism personality traits are prevalent among preclinical medical students and adversely affect their academic performance. Understanding the general personality traits present among medical students and its relationship with academic performance can provide valuable input for further medical education programme development.
Pap Smear Practices among Female Healthcare Professionals in Indonesia and Their Associated Factors Ramli, Richelle; Angelina
Medicinus Vol. 14 No. 1 (2024): October
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v14i1.9226

Abstract

Introduction : Cervical cancer is the fourth most frequent disease in women worldwide. However, pap smear coverage in Indonesia remains below the target. The purpose of this study was to describe pap smear practice among female healthcare professionals and its associated factors. Methods : This cross-sectional study was conducted from August 2022 to June 2023 among married female healthcare professionals of reproductive age who worked in Kelapa Dua district, Tangerang, Banten, Indonesia. Three general hospitals, two primary clinics, and one community health center were involved in this study. Data was collected using a self-administered questionnaire and analyzed using a chi-square test. Results : From 236 respondents, only 80 respondents (33.9%) had pap smear tests. The most common reasons for not doing the test were lack of time and having not experienced any of the symptoms. Those who were doing the pap smear tests were likely to be more than 40 years old (OR 29.900; 95% CI 9.595 – 93.172; p<0.001), married for more than 10 years (OR 28.737; 95% CI 9.955 – 82.955; p<0.001), multiparous (OR 6.941; 95% CI 2.706 – 17.805; p<0.001), and have higher economic income (OR 7.333; 95% CI 1.443 – 37.274; p=0.020). Female healthcare professionals other than medical practitioners, nurses, or midwives were less likely to do the pap smear tests (OR 0.370; 95% CI 0.167 – 0.823; p=0.02). Conclusion: Pap smear practice among female healthcare professionals in Indonesia was inadequate. Age, marriage duration, parity status, types of healthcare professionals, and socioeconomic status were significantly associated with pap smear practice.
Relationship Between the Level of Knowledge and Attitude Towards Maternal Behavior of Stunting Prevention at Bojong Nangka Community Health Center in Tangerang District Tanara, Arron; Rivami, Dwi Savitri
Medicinus Vol. 14 No. 1 (2024): October
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v14i1.9229

Abstract

Background: Stunting is one of the major health problems in Indonesia. In 2022, the prevalence of stunting in Indonesia was 21.6%, and there were still 9,200 cases of stunting in Tangerang District alone. Stunting prevention can be done since pregnancy. It is estimated that stunting prevention behaviors among pregnant women is related to their knowledge and attitudes. Puskesmas Bojong Nangka was a community health center in Tangerang that treated stunting but has no data on this matter. Methods: This study used a cross-sectional study design. Data on the level of knowledge, attitudes, and behaviors in stunting prevention was collected using questionnaires and further was analyzed using the Chi-square test. Result: From 96 respondents, it was found that the majority (63.5%) had a good level of knowledge on stunting prevention. Most respondents also had a good attitude towards stunting prevention (83.3%). There were 72 respondents (75%) who had recommended stunting prevention behaviors. Bivariate analysis showed that there was a significant relationship between knowledge level and stunting prevention behaviors (P value < 0.001; OR 7.29; 95% CI 2.6 – 20.39) but there was no significant relationship between attitudes and stunting prevention behaviors (P value = 1; OR 1; 95% CI 0.29 – 3.45). Conclusions: There was a significant relationship between the level of knowledge towards stunting prevention behaviors among pregnant women at Bojong Nangka Community Health Center, Tangerang District.
Characteristics of COVID-19 Therapy Based on Disease Severity at Siloam Kebon Jeruk Hospital Tjahyanto, Teddy; Herwanto, Velma
Medicinus Vol. 14 No. 1 (2024): October
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v14i1.9233

Abstract

Introduction : COVID-19 is an infectious disease that can cause acute respiratory syndrome by droplet transmission. Along with the very fast spread of the virus which occurs in almost all countries, it is necessary to have therapies that can reduce the morbidity and mortality of patients infected with COVID-19. Various factors affect the administration of therapy so a management guideline is needed for medical personnel so that the administration of therapy can be consistent and efficient in accordance with scientific evidence. This study aims to determine the characteristics and therapeutic options of COVID-19 patients based on the severity of the disease so it can be an evaluation for policymakers and health workers in providing COVID-19 therapy. Methods : This type of research is descriptive, and the research design is cross-sectional with a total population sampling. The study was conducted at Siloam Kebon Jeruk Hospital with a total of 135 respondents from secondary medical record data. Results : The observed data include the characteristics of the respondents and the therapies for COVID-19 patients, which consist of antiviral, anti-inflammatory, and anticoagulant treatments. Based on the collected data, COVID-19 patients were predominantly male (55.6%) with an average age of 55 years. Many patients presented with moderate severity without requiring oxygen (34.1%) and were classified as having referred outcomes (47.4%). Antiviral therapy using favipiravir was predominantly administered to patients with mild to moderate severity, while remdesivir was mostly given to those with moderate to severe severity. Corticosteroids, such as dexamethasone and methylprednisolone, were the preferred choice for anti-inflammatory therapy (72.2%). Heparin was the most commonly used anticoagulant therapy across all severity levels, and antibiotics were administered to the majority of patients infected with COVID-19 (73.3%). Conclusions : Evaluation of the low rate of use of corticosteroids and anticoagulants in COVID-19 patients is needed.
Predictive Value of Optic Nerve Sheath Diameter in Subarachnoid Hemorrhage: A Systematic Review and Meta-Analysis Tjahyanto, Teddy; Suryakanto, Milani
Medicinus Vol. 14 No. 1 (2024): October
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v14i1.9240

Abstract

Introduction : Optic nerve sheath diameter (ONSD) is a promising non-invasive marker for elevated intracranial pressure (ICP), potentially aiding in the prognostication of subarachnoid hemorrhage (SAH) outcomes. This study aimed to evaluate the predictive value of ONSD for poor outcomes in SAH patients, defined by the Glasgow Outcome Scale (GOS). Methods : A systematic review and meta-analysis were conducted, including studies from 2010 to 2021 that examined the relationship between ONSD and outcomes in SAH patients. A total of 615 patients were analyzed, with mean ages ranging from 54.1 to 58.8 years, and a predominance of males (38.2%). SAH severity was stratified using the Hunt and Hess classification, ranging from Grade 1 to Grade 5. The QUADAS-2 tool assessed the risk of bias, and the GRADE framework evaluated evidence certainty. Results : The pooled analysis revealed moderate predictive accuracy for ONSD in determining poor outcomes, with a pooled proportion of 0.70 (95% CI: 0.61–0.78). Significant heterogeneity (I² = 77.4%, p = 0.004) was observed, likely due to variability in ONSD thresholds, measurement techniques, and timing. Funnel plot analysis suggested potential publication bias, although further statistical testing is needed. Conclusions : ONSD demonstrates potential as a non-invasive tool for predicting poor outcomes in SAH patients. However, significant heterogeneity and moderate accuracy highlight the need for standardization of ONSD thresholds and measurement protocols. Further multicenter studies are required to validate its clinical utility and integrate it into comprehensive prognostic models.
Bereavement as A Risk Factor for Depression in The Elderly: An Evidence Based Case Report Andoko, Dewanto; Handoko, Marshel Timotius; Cipta, Darien Alfa
Medicinus Vol. 14 No. 1 (2024): October
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v14i1.9242

Abstract

Background: Depression disorder among the elderly population is a serious issue that is often underdetected and undertreated. Depression can lead to functional impairments, which are comparable to or even worse than those in individuals with chronic conditions such as heart and lung diseases. Bereavement is believed to be one of the risk factors for depression in the elderly. This literature search aims to explore bereavement as an etiology of depression in the elderly. Method: A structured search was conducted using the PubMed, Cochrane, and Science Direct databases, using tailored keywords aligned with the clinical question to obtain relevant results. Results: The search and selection process yielded one selected article that was deemed relevant to the case. This article provided a summary of evidence concerning the relationship between bereavement and the emergence of depression diagnosis in the elderly. Conclusion: The results of this systematic review and meta-analysis indicate that bereavement increases the risk of depression in the elderly. However, further studies are still needed to elucidate the mechanisms underlying depression in the elderly.
Clivus Chordoma: Case Report and Current Considerations on Endoscopic Endonasal Trans-Sphenoid Surgery with Neurosurgeon-Otolaryngologist Collaboration Lekatompessy, Michael; Widyakrisna, Albertus Boyke Raditya; July, Julius
Medicinus Vol. 14 No. 1 (2024): October
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v14i1.9245

Abstract

Chordomas, infrequent malignancies primarily located along the craniospinal axis, showcase gradual growth and localized bone destruction, with the clival region involved in approximately 25-35% of cases. Headaches accompanied by neurological deficits are the typical clinical presentations. Complete surgical resection is the mainstay, with recent collaborative efforts between otorhinolaryngologists and neurosurgeons leading to a positive shift from traditional craniotomic procedures to endoscopic endonasal approaches, fostering minimally invasive techniques and utilizing endoscopy for primary visualization across the neuraxis. Furthermore, the concept of team surgery has been introduced, involving simultaneous contributions from ENT surgeons and Neurosurgeons at all stages of the procedure, including the approach, resection, and reconstruction phases. This report presents a series of two successful cases of clival chordomas managed using the endoscopic endonasal approach at Siloam Hospital Lippo Village This indicates its potential as a viable surgical choice, particularly within medical centers that possess the necessary specialties. Successful implementation is notably enhanced through collaborative efforts between otolaryngologists and neurosurgeons, underscoring the significance of interdisciplinary teamwork.
Identification and Interpretation of Spinal Cord Injuries in Robbery Victims: A Forensic Review Kusumaningrat, Donald Rinaldi; Wahjoepramono, Eka Julianta; Purnamasari, Dewi
Medicinus Vol. 14 No. 1 (2024): October
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v14i1.9247

Abstract

Robbery is intrinsically a violent crime and is defined as the original criminal plan of the perpetrator by committing robbery, by force committed on occasion or with the pretext of robbery. Strangulation by ligature occurs when an external force is applied to the neck causing various traumatic pathologies. If the injury is severe enough, cerebral perfusion and oxygen delivery are compromised and can lead to asphyxia and rapid neuronal death. These injuries can be encountered in a variety of clinical scenarios and may be present in suicide attempts, sports injuries, motor vehicle trauma, and may have implications in the fields of criminology and forensic pathology. In this case, a 66-year-old woman who was a victim of a robbery suffered a neck injury. After examination, there was a fracture in the cervical spine and was diagnosed with spinal cord trauma. As a result of this injury, the victim suffered permanent paralysis. The perpetrators of the robbery are threatened with criminal penalties under 364 KUHP and/or Article 351 No 3 KUHP.
Superficial Spreading Cervical Squamous Cell Carcinoma to Endometrium: A Rare Case Report Limanto, Jennifer Jesse; Prasetiyo, Patricia Diana; Djohansjah, Alexy Oktoman; Chandra, Shally
Medicinus Vol. 14 No. 1 (2024): October
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v14i1.9250

Abstract

Introduction: Squamous cell carcinoma (SCC) was the most common variant of cervical cancer with metastases potential to many organs, commonly parametrium and vagina, but in a rare condition can also spread to endometrium. Further evaluations are needed since superficial spreading of cervical SCC are related to poorer outcomes. Case Presentation: A 62 y.o, post-menstrual, P3A0 women came with complaint of vaginal discharged mixed with blood since 6 months ago. Pap smear result suggestive of malignancy so the patient undergo guided biopsy from endocervix that revealed finding similar to carcinoma intraepithelial (CIN) 3. The patient underwent TAH-BSO operation. Microscopic examination from cervix showed tumor cell with round nuclei, prominent nucleoli, pleomorphic, hyperchromatic, increased nuclear-cytoplasm ratio in whole epithelial layer. Microscopic examination from endometrium showed epithelial squamous cell proliferation in almost 98% endometrial tissue and atypical cell nuclei, consistent with tumor founded in cervix. The final diagnosis was superficial endometrial spreading SCC with moderate differentiation. Immunohistochemistry (IHC) assay with p16 showed positive result in endometrium. Patient then consulted to gynecologist – oncology specialist for further treatment and evaluation. Conclusion: Superficial spreading of cervical SCC to endometrium was a rare finding. Detection of SCC in endocervix can be considered as predictor for proximal spreading of cervical SCC so further examination like endometrial curretage are suggested to assist the early detection. IHC assay with p16 resulted positive in our patient suggesting that endometrial SCC in this patient was correlated with HPV infection that commonly find in cervical cancer.

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