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Pharmed: Journal of Pharmaceutical Science and Medical Research

pharmed
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Published by Universitas PGRI Madiun

ISSN : 26144840 EISSN : 26146118 DOI : -

Core Subject : Health,

Medicine & Pharmacology Public Health

Journal of Pharmaceutical Science and Medical Research is a pharmaceutical journal which publish twice a year, on February and August. Various topics of pharmacys and health that can be accepted in this journal are: Pharmaceutical sience; Herb medicine; Medical; Health; Biomedical; Pharmacoepidemiology.

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Articles 5 Documents

Search results for , issue "Vol 1, No 1 (2018)" : 5 Documents clear

ETNOBOTANI TANAMAN ANTIPIRETIK MASYARAKAT DUSUN MESU BOTO JATIROTO WONOGIRI JAWA TENGAH Arum Suproborini; Mochamad Soeprijadi Djoko Laksana; Dwi Fitri Yudiantoro
Pharmed: Journal of Pharmaceutical Science and Medical Research Vol 1, No 1 (2018)
Publisher : Universitas PGRI Madiun

Traditional medicine in Indonesia has been known to the public long before formal health services with modern medicine. Indonesia has many species of plants that have properties to cure various diseases and some other useful properties for human health. Antipyretic plants are plants that have the property as a febrifuge. The content of flavonoids in plants merit as a reliever fever (antipyretic). This study aims to determine the garden plants that can be utilized by the community as a febrifuge. (antipyretic). The research method used is survey method. The location of the observation and sampling of the plants was done by purposive random sampling technique by plot plot size 2x2 meter, 5x5 meter (adjust the location of the land). Based on research and observation, there are 8 species of antipyretic plants tumeric (Curcuma domestica), papaya (Carica papaya), dadap (Erythrina sp), hibiscus (Hibiscus rosasinensis), rambutan (Nephelium lappaceum), banana ( Musa paradisiaca), soursop (Annona muricata), and yam (Pachirrhyzus erosus) which can be utilized by the local community.

PENYULUHAN KESEHATAN RUTIN PUSKESMAS UNTUK MENCEGAH SEKOLAH DASAR DENGAN KEJADIAN DBD DI KOTA MADIUN TAHUN 2017 Puri Ratna Kartini; Santi Martini
Pharmed: Journal of Pharmaceutical Science and Medical Research Vol 1, No 1 (2018)
Publisher : Universitas PGRI Madiun

Dengue Hemorrhagic Fever (DHF) is still a health problem in Madiun City. Based on data from the Madiun City Health Office (2011-2015) there has been a significant increase in DHF incidence over the past 5 years. Most DHF patients in Madiun City are elementary school children. This indicates that the program of DHF especially in primary school in Madiun is still less effective, especially routine health counseling by the heakth service centre related to PSN through 3M plus activities. This study aims to analyze the influence of routine health counseling by the health service centre to the incidence of DHF in Primary School in Madiun City. This research is an observational analytic research with case control design. The population in this study is divided into 2 groups, namely the case population (SD with DHF incidence) of 33 SD and control population (SD not with DHF incidence). The sample in this study is divided into 2 groups, namely the case sample (SD with selected DHF incidence) of 30 SD and control sample (SD not with DHF incidence) of 30 SD. Sampling technique is by Simple Random Sampling. From the result of the analysis test, it is found out that the routine health education of Puskesmas has an effect on the occurrence of DHF in Primary School in Madiun City (p = 0,001).

UJI TOKSISITAS EKSTRAK ETANOL KAYU CEREMAI (Phyllanthus acidus L) TERHADAP LARVA UDANG Artemia salina DENGAN METODE BRINE SHRIMP LETHALITY TEST (BST) Desi Kusumawati
Pharmed: Journal of Pharmaceutical Science and Medical Research Vol 1, No 1 (2018)
Publisher : Universitas PGRI Madiun

The use of Otaheite gooseberry wood as a traditional medicine needs to be supported by scientific information about the efficacy and side effect. The objective of this research is to prove the presence of toxicity potency in ethanol extract of otaheite gooseberry wood using BST methods. An experimental research. Total sampel were 160 Brine shrimp (Artemia salina Leach) larvae. Ten larvae used in each 6 groups with 3 times replication. Each group was consecutively given 500 μg/ml, 300 μg/ml, 200 μg/ml, 100 μg/ml, 50 μg/ml, 0 μg/ml concentrate of ethanol extract of otaheite gooseberry wood, the sixth group was used as control. Data obtained by calculating amount of died larva in 24 hours after treatment. LC50 value was analyzed by probit analysis using SPSS 16.0 for windows,. Presumable compound contained in extract etanol Otaheite gooseberry wood in which have tokcixity testcase by “skrining fitokimia”. The average mortality of larvae at a concentration of 500, 300, 200, 100, 50, and 0 μg/ml consecutively were 9,33; 7,33; 4,67; 3,33; 2 and 0. The higher the extract concentration led to a growing number of high larval mortality. LC50 value of fruit extract of otaheite gooseberry wood was 275,035μg/ml. LC50 <1000 μg/ml indicates ethanol extract of otaheite gooseberry wood own a potential toxicity to larvae of Artemia salina Leach.

UJI AKTIVITAS ANTIBAKTERI EKSTRAK DAUN BINAHONG (Anredera cordifolia (ten.) Steenis) TERHADAP PERTUMBUHAN BAKTERI Staphylococcus aureus DAN Pseudomonas aeruginosa Ani Sulistyarsi; Nanda Wahyu Pribadi
Pharmed: Journal of Pharmaceutical Science and Medical Research Vol 1, No 1 (2018)
Publisher : Universitas PGRI Madiun

Medicinal plants have been used from generation to generation to prevent, heal and maintain health. The aim of this research is to know the effect of binahong leaf extract (Anredera cordifolia (ten.) Steenis) on the growth of Staphylococcus aureus and Pseudomonas aeruginosa bacteria. The design of the study was a complete randomized design of 7 treatments, 3 replications. Binary extract by maceration test using ethyl acetate. The concentration of binahong extract used control (0%), 25%, 30%, 35%, 40%, 45%, 50% for Staphylococcus aureus and Pseudomonas aeruginosa bacteria. Data were analyzed by ANOVA oneway test, correlation and linear regression. The result showed that binahong against Staphylococcus aureus bacteria at 25% concentration, on bacterium Pseudomonas aeruginosa: concentration 50%. In KBM extract binahong test of Staphylococcus aureus bacteria with concentration 50%, on bacterium Pseudomonas aeruginosa with 100% concentration. ANOVA oneway test results: there is a significant difference between treatments. The value of sig (0,000) <p (0.05). The higher the concentration of binahong extract, the more able to inhibit and kill the bacteria Staphylococcus aureus (r = -0,805), Pseudomonas aureginosa (r = -0.616). The results of phytochemical tests found polyphenolic compounds, alkaloids and flavonoids

SINTESIS DAN UJI AKTIVITAS SENYAWA 2-BROMO-4,5-DIMETOKSIKALKON TERHDAP SEL KANKER T47D SECARA IN VITRO Retno Aliyatul Fikroh
Pharmed: Journal of Pharmaceutical Science and Medical Research Vol 1, No 1 (2018)
Publisher : Universitas PGRI Madiun

Synthesis of chalcone derivated has been synthhesized, structurally determined, and the in vitro cytotoxic activityof T47D cell was evaluated. A novel 2-bromo-4,5-dimethoxychalcone was synthesized by Claisen-Schmidt condensation of acetophenone with 6-bromoveratraldehyde. The synthesis of chalcone was carried out by reflux condition (65°C) for 24 hours using ethanol as a solvent and NaOH as a catalyst. The results showed that these coumpoun produced 81% in yield. The purity of synthesized product was determined by Thin Layer Chromatography. Structure identification was performed by FT-IR and 1H dan 13C-NMR spectrometer. In vitro activity test indicated that 2-bromo-4,5-dimethoxychalcone was not active for inhibiting the growth of T47D with IC50 value more than 100 µg/mL.

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Puri Ratna Kartini

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Jawa timur

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Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name Puri Ratna Kartini

Contact Email puri@unipma.ac.id

Phone -

Journal Mail Official pharmed@unipma.ac.id

Editorial Address -

Location Kota madiun, Jawa timur INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
Puri Ratna Kartini

Contact Email
puri@unipma.ac.id

Phone
-

Journal Mail Official
pharmed@unipma.ac.id

Editorial Address
-

Location
Kota madiun,

Jawa timur

INDONESIA