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Journal of Pharmaceutical and Medicinal Research Sekolah Tinggi Ilmu Farmasi Makassar Perintis Kemerdekaan Street KM 13.7 90242 Makassar-Indonesia
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Journal of Pharmaceutical and Medicinal Sciences
ISSN : 25282824     EISSN : 2580328X     DOI : -
Core Subject : Health,
The Journal of Pharmaceutical and Medicinal Sciences (JPMS) pISSN 2528-2824; eISSN 2580-328X dedicated to publish original research papers, original research notes, invited topical reviews, mini-reviews, editorial commentary and news. Medicinal resources about exchange of information and understandings about people's use of plants, fungi, animals, microorganisms, minerals, their biological and pharmacological effects based on the principles established through international conventions. Pharmaceutical including drugs, pharmacokinetics, biopharmaceutics, pharmacodynamics, pro-drug developments, metabolic disposition of bioactive agents, dosage form design, protein-peptide chemistry and biotechnology specifically as these relate to pharmaceutical technology and targeted drug delivery.
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Articles 5 Documents
Search results for , issue "Vol 3 No 1 (2018): JPMS" : 5 Documents clear
Formulasi Sediaan Teh Herbal Celup Dari Daun Salam (Eugenia polyantha Wight.) Kombinasi Daun Sirsak (Annona muricata L.) Sebagai Alternatif Anti-Hipertensi Nirwati Rusli; Siti Hardiyanti Liasambu
Jurnal Farmasi dan Ilmu Pengobatan Vol 3 No 1 (2018): JPMS
Publisher : STIFA Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (232.245 KB) | DOI: 10.32814/jpms.v3i1.62

Abstract

Bay (Eugenia polyantha Wight.) leaf and soursop (Annona muricata L.) leaf contain flavonoids that have a protective effect on endothelial function as an anti-hypertensive while jasmine flower has a good odor. This study aims to formulate herbal tea bags from bay leaf, soursop leaf, and jasmine flower into tea bag that qualified physical evaluation. The dried leaves of each sample were putted in bag with various concentration then observe the physical characteristics. The result shows that tea bag was qualified according to SNI 01-4324-1996. The water content was 9.46% - 11.94%, total plate count (TPC) however mold and yeast counts (MYC) were 3 x 103 colonies/g and 1 x 104 colonies/g, respectively. However, FA was preferred by the panelists based on its color, odor and taste.
Deteksi Antimikroba Secara KLT- Bioautografi Ekstrak Buah Belimbing Wuluh (Averrhoa bilimbi Linn.) Yasnidar Yasir; Herlina Rante; Sitti Nur Aminah Emba Semsuli
Jurnal Farmasi dan Ilmu Pengobatan Vol 3 No 1 (2018): JPMS
Publisher : STIFA Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (219.978 KB) | DOI: 10.32814/jpms.v3i1.61

Abstract

Indonesia memiliki banyak tanaman yang digunakan sebagai obat salah satunya adalah belimbing wuluh (Averrhoa bilimbi L.). Penelitian ini bertujuan untuk mengetahui adanya aktivitas antibakteri dari buah A. bilimbi dan untuk mengetahui golongan senyawa kimia aktif dari buah A. bilimbi terhadap bakteri Escherichia coli dan Staphylococcus aureus secara KLT-Bioautografi. Buah A. bilimbi diekstraksi dengan metode maserasi menggunakan cairan penyari etanol 96% sedangkan metode difusi agar dilakukan untuk mengetahui aktivitas bakteri. Hasil penelitian menyatakan bahwa ekstrak etanol dan partisi buah A. bilimbi pada konsentrasi 10% dapat menghambat bakteri E. coli dan S. aureus. Identifikasi senyawa kimia aktif dari ekstrak etanol yang diduga mempunyai aktivitas antibakteri terhadap E. coli dan S. aureus secara KLT-Bioautografi secara berturut-turut yaitu senyawa terpenoid pada Rf = 0,11 dan 0,81. Sedangkan partisi n-heksana yaitu terpenoid yang dapat hanya mampu menghambat E. coli pada nilai Rf 0,78. Sehingga dapat disimpulkan bahwa ekstrak buah A. Bilimbi dapat digunakan sebagai alternative dalam menghambat pertumbuhan bakteri.
Analisis Kadar Residu Derifat Formalin Dalam Galon Isi Ulang yang Beredar di Daya, Makassar, Sulawesi Selatan Jeni Anti Barrang; Bela Chintya; Arianty Kurniastuty; Astuti Amin; Lukman Muslimin
Jurnal Farmasi dan Ilmu Pengobatan Vol 3 No 1 (2018): JPMS
Publisher : STIFA Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (260.892 KB)

Abstract

Using gallons as a main source of drinking water are increasing. Gallon packs are composed of plastic polymers that will decompose in sunlight exposure. This study aims to analyze the levels of formaldehyde residues in refill circulating in the Daya, Makassar, South Sulawesi. Formalin residues are determined by Schiff’s reagent. The results showed that 7 from 12 gallon contained formalin derivatives with a serius level (16.45 µg/mL).
Aktivitas Antibakteri Ekstrak Etanol Buah Wualae (Etlingera elatior (JACK) R.M. Smith) Wahyuni Wahyuni; Fadhliyah Malik; Andryani Ningsih; Wa Ode Sitti Zubaydah; Sahidin Sahidin
Jurnal Farmasi dan Ilmu Pengobatan Vol 3 No 1 (2018): JPMS
Publisher : STIFA Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (446.707 KB)

Abstract

Wualae (Etlingera elatior (Jack) R.M. Smith) belonging to Zingeberaceae that spread in South East Sulawesi, empirically used as staple and treatment. The aim of this research to determine the antimicrobial potential of ethanol extract fruit of E. elatior against gram positive (Staphylococcus aureus ATCC 25923 and Bacillus subtilis FNCC 0060), and gram negative (Pseudomonas aeruginosa ATCC 27853 and Salmonella enterica ATCC 14028) using cup-plate method. The antimicrobial activity based on the diameter of inhibition zone. The result shows that extract more potential to inhibit gram positive than gram negative while the highest inhibition illustrate by concentration of 20 mg/mL (inhibition zone= 5 mm). In conclusion, the extract of E. elatior no potent as antimicrobial candidate (category= weak).
Aktivitas Antibakteri Ekstrak Etanol Daun Pazote (Chenopodium ambrosioides L) Terhadap Escherichia coli Djois Sugiaty Rintjap; Roske Irma Korobu; Lidya E S Rumajar
Jurnal Farmasi dan Ilmu Pengobatan Vol 3 No 1 (2018): JPMS
Publisher : STIFA Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (135.865 KB)

Abstract

Infectious diseases still remain a major problem in tropical countries like Indonesia. Uncontrolled of antimicrobials consumption leads to the emergence of resistance. So new antimicrobial searches need to be carried out. One of the plants suspected of having antimicrobial activity was Pazote (Chenopodium ambrosioides L.). Extraction of C. ambrosioides leaves was carried out by maceration with 70% ethanol. Antimicrobial activity was carried out by Kirby-Bauer (modified) at concentrations of 5, 10, and 15% while the inhibitory zone was observed daily for 3 days. The results showed that the duration of contact did not affect to the diameter of the inhibitory zone. The largest inhibitory diameter is indicated by 15% was 12.33 mm. In addition, the ethanol extract of C. ambrosioides leaves has the potential as an antimicrobial against Escherichia coli.

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