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JURNAL FARMASIMED (JFM)
Published by Institut Kesehatan Medistra Lubuk Pakam
ISSN : -     EISSN : 26550814     DOI : -
Core Subject : Health,
Medicine & Pharmacology
Jurnal FARMASIMED (JFM) Volume I Nomor 1 Periode Mei - Oktober Tahun 2018. Jurnal ini memberikan ruang bagi akademisi, peneliti dan pengguna hasil penelitian dan pengabdian untuk mendiseminasikan, menginformasikan, mendiskusikan dan menggunakan hasil penelitian dan pengabdian sebagai upaya meningkatkan kualitas kebijakan di bidang farmasi yang berbasis ilmiah dan dapat dipertanggung jawabkan. Jurnal ini menyajikan hasil penelitian, pengabdian masyarakat serta artikel ilmiah di bidang farmasi.
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Articles 15 Documents
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Search results for , issue "Vol 4 No 2 (2022): Jurnal Farmasimed (JFM)" : 15 Documents clear
ANTIFUNGAL EFFECTIVENESS OF LEAF ETHANOL EXTRACT WAKE UP (COLEUS AMBOINICUS)AGAINST THE FUNGI CANDIDA ALBICANS Situmorang, Novidawati Boru
Jurnal FARMASIMED (JFM) Vol 4 No 2 (2022): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v4i2.1061

Abstract

Daun bangun-bangun (Coleus amboinicus), merupakan Salah satu tumbuhan yang berpotensi sebagai obat dan telah sering digunakan oleh masyarakat. Kandungan senyawa Flavonoid dalam daun Bangun-bangun diyakini memiliki manfaat dan berpotensi sebagai antijamur terhadap Candida albicans. Selain itu adanya resistensi akan obat kimiawi sehingga pengobatan yang bersumber dari alam mulai dikembangkan. Tujuan dari penelitian ini yaitu untuk mengetahui aktivitas antijamur ekstrak etanol daun Bangun-bangun (Coleus amboinicus) terhadap bakteri Candida albicanss. Penelitian diawali dengan melakukan pemeriksaan metabolit alkaloid, saponin, flavanoid, tanin dan kemudian pengujian aktivitas antijamur terhadap Candida albicans dengan beberapa konsentrasi yaitu 5, 10, dan 15%, metode difusi agar kertas cakram. Hasil skrining fitokimia daun Bangun-bangun menunjukkan adanya alkaloid, tanin, flavonoid, dan saponin. Hasil pemeriksaan karakteristik serbuk simplisia daun bangun-bangun didapat kadar air 9,27%, kadar sari larut air 14,5%, kadar sari larut etanol 9,76%, sesuai dengan materia medika indonesia. Hasil skrining fitokimia yang didapat yaitu fenolik, flavonoid, saponin, steroid/triterpenoid. Pengujian aktivitas antijamur ekstrak etanol daun bangun-bangun menunjukkan diameter zona hambat pada konsentrasi 5%, 10%, 15%, adalah 14,47 mm, 15,46 mm, 16,34 mm. Maka dapat disimpulkan bahwa semakin tmeningkat konstrasi ekstrak,makasemakin besar diameter zonahambatnya.
ANTIBACTERIAL ACTIVITY OF ETHANOL EXTRACT PACAR AIR LEAVES (IMPATIENS BALSAMINA L.) AGAINST PROPIONIBACTERIUM ACNE Octora, Debi Dinha; Waruwu, Krismawati
Jurnal FARMASIMED (JFM) Vol 4 No 2 (2022): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v4i2.1067

Abstract

ABSTRAK Aktivitas antibakteri Impatiens balsamina L. telah dipelajari selama bertahun-tahun. Daun inai air mengandung flavonoid, saponin dan tanin yang memiliki kemampuan untuk menghambat pertumbuhan bakteri. P. acnes merupakan salah satu jenis bakteri yang dapat menyebabkan infeksi pada jerawat. Salah satu tujuan penelitian ini adalah untuk mengetahui aktivitas antibakteri ekstrak etanol daun inai air dan konsentrasi yang paling efektif dalam menghambat bakteri P. acnes. Penelitian ini merupakan penelitian eksperimen murni. Daun inai air dimaserasi dengan pelarut etanol 96%. Uji aktivitas antibakteri dilakukan dengan metode difusi cakram. Penelitian dilakukan dengan 3 variasi konsentrasi yang berbeda. Hasil penelitian menunjukkan adanya aktivitas antibakteri pada setiap konsentrasi. Kesimpulannya ekstrak etanol daun inai dengan konsentrasi 25%, 50% dan 75% memberikan penghambatan pertumbuhan bakteri paling efektif dengan konsentrasi 25%, 50% dan 75% yang termasuk dalam kategori kuat. Saran diharapkan bagi peneliti selanjutnya untuk dapat menguji bakteri lain dan membuat formulasi dari ekstrak daun inai air. ABSTRACT The antibacterial activity of Impatiens balsamina L. has been studied for many years. Water henna leaves contain flavonoids, saponins and tannins which have the ability to inhibit bacterial growth. P. acnes is one type of bacteria that can cause infection in acne. One of the objectives of this study was to determine the antibacterial activity of the ethanol extract of henna water leaves and the most effective concentration in inhibiting P. acnes bacteria. This research is a pure experimental research. Water henna leaves were macerated with 96% ethanol as solvent. Antibacterial activity test was carried out by disc diffusion method. The research was conducted with 3 different concentration variations. The results showed that there was antibacterial activity at each concentration. The conclusion is that the ethanol extract of henna leaves with concentrations of 25%, 50% and 75% gave the most effective bacterial growth inhibition with concentrations of 25%, 50% and 75% which were included in the strong category. Suggestions are expected for further researchers to be able to test other bacteria and make formulations from water henna leaf extract.
TEST THE ANTIBACTERIAL ACTIVITY OF ETHANOL EXTRACT OF CRASSOCEPHALUM CREPIDIOIDES LEAF AGAINST STREPTOCOCCUS PYOGENES anggraeni, Ratih; Lingga, Nola Monalisa
Jurnal FARMASIMED (JFM) Vol 4 No 2 (2022): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v4i2.1082

Abstract

The ethanol extract of Crassocephalum crepidioides leaves was tested against Streptococcus pyogenes bacteria. Extracts from the leaves of Crassocephalum crepidioides are known to have the potential to suppress microbial growth because contain active compounds of alkaloids and flavonoids. The test was carried out by the diffusion method using disc paper that had been soaked in a solution of ethanol extract of Crassocephalum crepidioides leaves with a concentration of 20%, 30%, 40%, 50%. Amoxicillin as a positive control and DMSO as a negative control. It is known that the inhibition of bacterial growth at a concentration of 20% the inhibition zone is 11mm, the concentration of the inhibition zone of 30% is 11.8mm, the concentration of 40% of the inhibition zone is 12.2mm, the concentration of 50% is the inhibition zone is 12.6mm. The higher the concentration of the ethanol extract of Crassocephalum crepidioides leaves, the wider the area of inhibition against Streptococcus pyogenes bacteria.
HAND AND BODY LOTION FORMULATION OF AVOVO SKIN EXTRACT (PERSEA FREESIMA GAERTN) AS A MOISTURIZER Rani, Yosi Darmi; Delima, Cici
Jurnal FARMASIMED (JFM) Vol 4 No 2 (2022): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v4i2.1084

Abstract

Avocados have been used by the community for generations as traditional medicinal ingredients. Avocado (Persea Americana Mill) is a plant that contains many compounds that are antioxidants. Flavonoids and tannins are compounds that have antioxidant activity which are suspected as sunscreens. Research Objectives To determine the concentration of avocado skin extract (Persea Gratissima Gaertn) 3%, 5%, 7% as hand and body lotion. Laboratory experimental research. Based on the results of the one-way ANOVA test that was used to analyze the avocado peel extract as skin flexion at blank concentrations of 3% concentration, 5% concentration and 7% way concentration, the mean Squaer result was 0.333 with results 0.052 > 0.05. it can be said that the results of the table above indicate that avocado skin can be used as skin moisture. Conclusion Based on the results of community tests conducted by the three hand and body lotion formulas, avocado skin extract that has been stored for 28 days of storage shows that the skin of the fruit can be used as moisture skin.
MANUFACTURED OF LOTION FROM AVOCADO LEAF ETHANOL EXTRACT ( PERSEA AMERICANA MILL) AS SKIN MOISTURIZER Br Manik, Margaretta Olivia; Mahmiara, Nopri
Jurnal FARMASIMED (JFM) Vol 4 No 2 (2022): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v4i2.1088

Abstract

Abstrak Alpukat diformulasikan menjadi lotion, berdasarkan penelitian sebelumnya daun nya mengandung antioksidan tinggi yang diwakili dengan senyawa flavonoid. Tujuannya untuk mengetahui sediaan dari ekstrak etanol daun alpukat dapat melembabkan kulit. Penelitian ini dengan metode eksperimen. Ekstrak daun alpukat dilakukan dengan proses maserasi. Pemeriksaan sediaan dilakukan pada penelitian ini adalah uji skrining fitokimia, uji Ph, uji iritasi dan uji kelembapan kulit dengan konsentrasi 3% dan 5%. Abstract Avocado is formulated into a lotion, based on previous research, its leaves contain high antioxidants which are represented by flavonoid coumpounds . The aim was to determine whether the preparation of avocado leaf ethanol extract could moisturerize the skin. This research uses the experimental method. Leaf was carried out by a maceration process. Examination of the preparation carried out in this study were phytochemical screening tests, pH, Irritation and skin moisture with concentration of 3% and 5%.

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