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Jurnal Respirasi (JR)

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Published by Universitas Airlangga

ISSN : 24070831 EISSN : 26218372 DOI : -

Core Subject : Health,

Health Professions Medicine & Pharmacology Public Health

Jurnal Respirasi is a National journal in accreditation process managed by Department of Pulmonology & Respiratory Medicine Faculty of Medicine Airlangga University - Dr. Soetomo General Hospital, Surabaya. Publish every January, May, September every year with each of 5 (five) complete texts in Indonesian.

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Articles 7 Documents

Search results for , issue "Vol. 4 No. 3 (2018): September 2018" : 7 Documents clear

Problem Terapeutik pada Empiema Terlokulasi karena Tuberkulosis : [Theurapetic Problem in Tuberculosis Loculated Empyema] Isnin Anang Marhana; Amelia Tantri Anggraeni
Jurnal Respirasi Vol. 4 No. 3 (2018): September 2018
Publisher : Faculty of Medicine Universitas Airlangga

Background: Pleural effusion is the most common complication of pulmonary tuberculosis (TB). Some coexist with secondary infection could worsen clinical presentation as empyema. The incidence of pleural effusion in the early stage of empyema due to TB infection is about 31%. Somehow, untreated empyema increased in-hospital mortality. Case: A woman with unregulated diabetes mellitus was referred with organized empyema. The etiology of empyema is based on a specific process of TB infection with the ADA value of empyema fluid was 128 mg/dl. We decided to perform decortication with the result loculated empyema and bronchopleural fistula 2 cm in the inferior lobe of the right lung. The patient did not recover well. Unfortunately, fluidopneumothorax was found on a chest CT scan with contrast. Thoracotomy was performed and another bronchopleural fistula was found which length was about 1 cm in superior lobe of the right lung. Discussion: The worsening condition of the patient was caused by the occurrence of postoperative bronchopleural fistula. It was visualized as pulmonary TB with perforation of cavity nessessity. On the other hand, the condition could be worsened by the hyperglycemic state in an immunocompromised individual. Summary: Loculated empyema is a condition caused by bronchopleural fistula, the presence of a connecting cavity between pleural and bronchus which occurred less than 48 hours. Local and systemic factors might explain the development of bronchopleural fistula. Well management of the loculated empyema by knowing the etiology could improve the life survival of the patient.

Front Matter Vol 4 No 3, 2018 Front Matter
Jurnal Respirasi Vol. 4 No. 3 (2018): September 2018
Publisher : Faculty of Medicine Universitas Airlangga

Tumor Angiogenesis Farah Fatma Wati; Whendy Wijaksono
Jurnal Respirasi Vol. 4 No. 3 (2018): September 2018
Publisher : Faculty of Medicine Universitas Airlangga

Tumor angiogenesis, a process in which blood vessels penetrate and grow in a tumor environment, is needed for oxygen and nutrient supply and plays an important role in the survival of solid neoplasms. Angiogenesis does not only have a role in tumor development and metastasis, but also acts as marker of cancer itself (hallmark of cancer). Several mechanisms of angiogenesis include vasculogenesis, sprouting angiogenesis, intussusception microgrowth, and vasculogenic mimicry. Knowing these different mechanisms will be helpful in choosing the best agents or drugs for cancer therapy. The first anti-angiogenic drug used was bevacizumab, a monoclonal antibody, directed against VEGF. Bevacizumab has significant clinical benefits in patients with advanced NSCLC.

Gambaran Radiografi Tuberkulosis Paru Multidrug-Resistant: Studi Retrospektif di Rumah Sakit Umum Dr. Soetomo Surabaya : [Chest Imaging in Multidrug-Resistant Pulmonary Tuberculosis: Retrospectif Study in Dr. Soetomo General Hospital Surabaya] Stephanie Christina Sulaiman; Lulus Handayani; Mohammad Yamin Sunaryo Suwandi; Soedarsono Soedarsono
Jurnal Respirasi Vol. 4 No. 3 (2018): September 2018
Publisher : Faculty of Medicine Universitas Airlangga

Background: Multidrug-resistant pulmonary tuberculosis (MDR-TB) is a major health problem worldwide. Prompt diagnosis is necessary for insuring appropriate therapy to lower morbidity and mortality, as well as to prevent disease transmission. Determination of drug-resistance patterns through microbiological examination is sometimes challenging, especially when the sputum acid-fast bacilli smear is negative. Therefore, it is worthwhile to investigate whether there may be radiographic patterns suggesting MDR-TB infection. The objective of this study was to evaluate the radiographic features of MDR-TB. Methods: From September 2015 to March 2018, 167 patients with microbiologically proven MDR-TB were enrolled in the study. All radiographs were obtained before the patients received MDR-TB chemotherapy regimen. Posterior-anterior chest radiography was performed using digital radiography system (Hitachi Radnext50 500mAs) and retrospectively reviewed as digital raw data. Results: Based on severity category, 60% had severe lesion, 31% had moderate lesion, and only 9% had mild lesion. The most frequently observed findings were ground glass opacity or consolidation, noted in 96% patients, with bilateral lung involvement in 81% patients; fibrosis (95%), cavity (78%; 87% of which were multiple), interstitial opacities (53%), pleural thickening and mediastinal shift (59%). Other radiological findings were calcification (16%), emphysema (13%), lung destruction (12%), atelectasis (10%), nodule (8%), bullae (8%), bronchiectasis (5%), miliary pattern (1%), pleural effusion (25%), pneumothorax (1%), and hilar lymphadenopathy (14%) which predominantly unilateral. Conclusion: The presence of severe pulmonary lesion, ground glass opacity or consolidation with bilateral lung involvement, fibrosis, multiple cavities, interstitial opacities, pleural thickening, and mediastinal shift are the main features of MDR-TB.

Metastasis Kanker Paru: [Lung Cancer Metastatic] Anna Febriani; Achmad Furqon
Jurnal Respirasi Vol. 4 No. 3 (2018): September 2018
Publisher : Faculty of Medicine Universitas Airlangga

Metastasis is the ability of cells to escape from the primary tumor, then enter the circulation to the distant tissue and form a secondary tumor. There are hemodynamic hypothesis (anatomical) and seed and soil hypothesis (molecular recognition). Tumor cells spread through several ways: percontinuitatum, lymphogen, hematogenous, transluminal, transcelomic, and iatrogenic. The stages of the metastasis process include: detachement, invasion, intravasation, circulation, extravasation, and angiogenesis. Predilection of lung cancer metastasis often happens in the brain, bones, liver, and adrenal glands. The spread of lung cancer metastasis to the brain, bone, and liver occurs hematogenously. Adrenal glands metastasis ipsilateral occurs lymphatically, while contralateral occurs hematogenously. Lung cancer is often diagnosed at an advanced stage, because in the early stage it is often asymptomatic. Metastasis of lung cancer to distant organs is the most cause of lung cancer deaths.

Back Matter Vol 4 No 3, 2018 Back Matter
Jurnal Respirasi Vol. 4 No. 3 (2018): September 2018
Publisher : Faculty of Medicine Universitas Airlangga

Pneumotoraks Bilateral dan Transaminitis Non Spesifik pada Silikosis: [Bilateral Pneumothorax and Transaminitis in Silicosis Patient: A Case Report] Sahrun Sahrun; Winariani Koesoemoprodjo; Ariani Permatasari
Jurnal Respirasi Vol. 4 No. 3 (2018): September 2018
Publisher : Faculty of Medicine Universitas Airlangga

Background: Silicosis is a fibrosis in the lung caused by inhalation, retention, and reaction to crystalline silica. The prevalence rate is potentially increasing throughout the world. Cases of bilateral spontaneous pneumothorax and transaminitis due to complications of silicosis are very rare. In this case, the patient was presented with bilateral secondary spontaneous pneumothorax as well as in the development of the diagnosis of silicosis, liver dysfunction, and pneumonia. Case: A 36-year-old male was admited to hospital with shortness of breath, the patient was once stone artisans for 7 years, rarely using PPE. Bilateral pneumothorax was established based on the results of clinical and radiological examinations. HRCT showed that it supported silicosis, left fluidopneumothorax, and right pneumothorax. Bronchoscopy was not possible due to the incompatible conditions and subsequently the patient was examined for silica levels from both plueral fluid with significant pleural silica. Summary: Diagnosis of pulmonary silicosis was done by clinical, radiological, and silica analysis of bronchial rinses, but certain conditions of silica could be found from pleural fluid. Silicosis therapy with complications until recently is only symptomatic, definitive therapy has not been found. Silicosis complications can be from pneumothorax bilateral (rarely), tuberculosis, transaminitis, and pneumonia. Conclusion: Pulmonary silicosis can be found from pleural fluid when the amount is large enough, fibrosis and extensive lung damage occurred. Silicosis can have an impact on pneumothorax, liver disorders, pneumonia, tuberculosis, and respiratory problems.

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Jl. Mayjen Prof. Dr. Moestopo 6-8 Surabaya 60286 Indonesia

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Jawa timur

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Journal Mail Official respirasi@journal.unair.ac.id

Editorial Address Jl. Mayjen Prof. Dr. Moestopo 6-8 Surabaya 60286 Indonesia

Location Kota surabaya, Jawa timur INDONESIA

Abstract

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Contact Name
-

Contact Email
-

Phone
-

Journal Mail Official
respirasi@journal.unair.ac.id

Editorial Address
Jl. Mayjen Prof. Dr. Moestopo 6-8 Surabaya 60286 Indonesia

Location
Kota surabaya,

Jawa timur

INDONESIA