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Penentuan Jenis Kelamin berdasarkan Sidik Hypothenar Widya Iswara, Raja Al Fath; Rohmah, Intarniati Nur; Santosa, Santosa; Relawati, Ratna
Medica Hospitalia : Journal of Clinical Medicine Vol. 7 No. 1 (2020): Med Hosp
Publisher : RSUP Dr. Kariadi

Background : Hypothenar regio in palmar is an area that is often contact with surfaces while doing the activity which can establish print or pattern of protruding line (ridge) that can be used in identification process. One of the important identification to sex determination. The aims of this study is to sex determination based on hypothenar print. Methods : The study was a cross sectional study. Subjects were 300 students underwent clinical clerkship in Forensic and Medicolegal Dr. Kariadi Semarang hospital during October-December 2017, age 21-26 years, male (n = 150) and female (n = 150). Hypothenar print measured by calculating the average number of ridge hypothenar palm on the side of the top, middle and bottom in each area measuring 5 mm x 5 mm. A Mann-Whitney test was performed to analyze the the difference between left and right hypothenar ridge. Spearman correlation test was conducted to measure the association of hypothenar prints and sex. Results : In male, the average number of hypothenar ridge on the right palm was 10 (7-12)/25 mm2, while the left palm 10 (7-13)/25 mm2. In female, the average number of hypothenar ridge on the right palm was 12 (8-16)/25 mm2, while the left hand was 12 (8-16)/25 mm2. The was a significant difference between the right hand hypothenar ridge (p = 0.008) and the left hand hypothenar ridge (p = 0.017) between male and female. There was a significant correlation between hypothenar prints and sex (p = 0.000). Conclusion : Hypothenar prints can be use in sex determiation where female have more hypothenar ridge count and density than male.

Hubungan Pengetahuan dan Persepsi Ibu dengan Pemanfaatan Layanan Provider Initiated HIV Testing Counselling di Maluku Nababan, Sudarwati; Papilaya, Maritjie Fransina; Udji Sofro, Muchlis Achsan
Medica Hospitalia : Journal of Clinical Medicine Vol. 7 No. 1 (2020): Med Hosp
Publisher : RSUP Dr. Kariadi

Latar belakang : Maluku Tenggara berada pada peringkat ke-2 tertinggi kasus HIV/AIDS dari 11 kabupaten di Maluku. Ibu rumah tangga di Wilayah Kerja Puskesmas Kolser rentan tertular HIV dari suaminya. Rumah tangga daerah ini 40% tidak tinggal bersama karena suami bekerja tidak menetap, selain itu di daerah ini juga terdapat lokalisasi. Ibu hamil yang memanfaatkan layanan Provider Initiated HIV Testing Counselling tahun 2017 sebanyak 76% dari 321 kunjungan, data ini menunjukkan Puskesmas Kolser belum mencapai target Maluku Tenggara terkait program yakni 89%. Tujuan : Mengetahui faktor yang mempengaruhi pemanfaatan layanan PITC oleh ibu hamil di Wilayah Kerja Puskesmas Kolser. Metode : Penelitian ini menggunakan metode observasional analitik pendekatan cross-sectional. Subjek 155 ibu hamil di Wilayah Kerja Puskesmas Kolser yang diperoleh dengan tehnik total sampling. Instrumen penelitian kuesioner, data dikumpulkan dengan metode face to face dan dianalisis menggunakan uji chi square dan regresi ogistik ganda metode backward Hasil : Terdapat hubungan pengetahuan (p=0,000), persepsi manfaat pemeriksaan HIV (p=0,007), dan persepsi kerentanan (p=0,040) dengan pemanfaatan layanan PITC. Ibu hamil yang mempunyai pengetahuan rendah beresiko 3,825 kali lebih besar untuk tidak memanfaatkan layanan PITC dibandingkan ibu hamil dengan pengetahuan yang tinggi. Simpulan : Pengetahuan ibu hamil merupakan faktor yang paling signifikan terkait pemanfaatan layanan PITC di Wilayah Kerja Puskesmas Kolser Maluku. Kata kunci : Ibu hamil, PITC, pengetahuan, HIV/AIDS Relationship Between Mother’s Knowledge and Perception with the Use of Provider Initiated HIV Testing Counselling in Maluku Background : Southeast Maluku district is ranked the 2th highest number of HIV/AIDS cases from 11 district in Maluku. Housewives in Kolser health center are at risk of contracting HIV from their husbands. Families in this area 40% do not live together, because the husband works non permanently. Another reasons is that in this area there are prostitute houses. Kolser health center is one of the Puskesmas that serves HIV testing in Southeast Maluku. Pregnant women who come to visit PITC in 2017 were 247 mothers out of 321 visits. Purpose : This study aims to explore the behavioural factors that influence pregnant women’s to PICT at the Kolser health center. Methods : This study employed a cross-sectional design. The sample of this study consists of 155 pregnant mothers in Puskesmas Kolser, selected by using total sampling. Data was collected using face to face interview by trained enumerators. Data were then analysed with chi-square test and logistic regression backward method. Results : The finding of this study is that there is a relationship between knowledge (p=0,000), perceived benefit (p=0,007), perceived susceptibility (p=0,040) with the visit of pregnant women to PITC. Compared to pregnant women who do not have sufficient on HIV/AIDS, those who have sufficient knowledge on HIV/AIDS was 3.825 times more likely to come visit PITC Conclusion : sufficient knowledge of pregnant women is the most significant factor related to the utilization of PITC in Kolser health center. Keywords : pregnant women, PITC, knowledge, HIV/AIDS

Perbedaan Jumlah Trombosit, Leukosit Dan Eritrosit Dengan Kecepatan Sentrifugasi Yang Berbeda Pada Pembuatan Platelet Rich Plasma Fajaryani, Dwi; Rahayu, Muji; Limijadi, Edward Kurnia Setiawan
Medica Hospitalia : Journal of Clinical Medicine Vol. 7 No. 1 (2020): Med Hosp
Publisher : RSUP Dr. Kariadi

Latar belakang : Platelet Rich Plasma (PRP) adalah plasma dalam jumlah sedikit dengan jumlah trombosit banyak, didapatkan melalui sentrifugasi. Trombosit dalam PRP penting untuk penyembuhan luka dan memperbaiki jaringan rusak. Kecepatan sentrifugasi berperan penting dalam memisahkan sel darah merah dengan plasma dan menghasilkan platelet konsentrat. Penelitian ini bertujuan untuk mengetahui perbedaan jumlah trombosit, leukosit dan eritrosit dengan kecepatan sentrifugasi yang berbeda pada pembuatan platelet rich plasma. Metode: Penelitian belah lintang pada orang sehat di laboratorium RSUP Dr. Kariadi Semarang bulan Juli 2018. Darah vena ditampung dalam tabung sitras dan Ethylenediaminetetraacetic acid (EDTA). Darah EDTA untuk pemeriksaan hematologi rutin dengan hematology analyzer, hasil normal dilanjutkan pembuatan PRP dari darah sitras 3,2 % dengan dua metode sentrifugasi, dengan kecepatan 100xg-400x selama 10 menit (metode PRP1) dan kecepatan 540xg-2270xg selama 10 menit (metode PRP2). Kedua produk PRP dilakukan pemeriksaan jumlah trombosit, leukosit dan eritrosit. Data dianalisis dengan uji Kruskall Wallis dan Mann Whitney, signifikan bila p< 0.05. Hasil : Sampel terdiri dari 35 orang responden. Terdapat perbedaan bermakna jumlah trombosit, leukosit dan eritrosit pada pembuatan PRP-1 dan PRP-2 (p<0.001) Simpulan : Terdapat perbedaan jumlah trombosit, leukosit dan eritrosit pada kecepatan sentrifugasi yang berbeda. Kecepatan sentrifugasi pada metode pembuatan PRP disarankan dalam pembuatan PRP. Kata kunci : PRP, trombosit, leukosit, eritrosit Background : Platelet Rich Plasma (PRP) consisting of small amounts plasma with many platelet, which was obtained by centrifugation process. The platelet in PRP are essential for wound healing and repair of damaged tissue. The centrifugation velocity plays an important role in separating red blood cells by plasma and producing concentrated-platelets. This study aims to determine differences the number of platelets, leukocytes and erythrocytes with different centrifugation rates on platelet rich plasma production. Methods: This cross sectional study was conducted on 35 healthy people in the laboratory of Kariadi Hospital Semarang in July 2018. The blood vein were collected in Citrate 3.2 % and Ethylenediaminetetraacetic acid (EDTA) tubes. Sample EDTA for complete blood counts, if the results were normal then continued with PRP preparation in 2 different methods centrifugation (PRP 1 at 100xg-400xg for 10 minutes and PRP 2 at 540xg-2270 xg for 10 minutes). Both of the PRP products were calculated the amounts of platelet, leukocytes, and erythrocytes. The data were analyzed by Kruskall Wallis and Mann Whitney, p < 0.05 was considered as significant. Results : There was a significant difference between PRP-1 and PRP-2 method in platelet counts, leukocytes count and erythrocytes count (p<0.001). Conclusion : There was differences in platelet count, leukocytes count and erythrocytes count with different centrifugation rate. Centrigugation rate on PRP-1 method is recommended in the production of PRP. Keyword PRP, platelets, leukocytes, erythrocytes

Faktor Risiko Air Bone Gap Pada Otitis Media Supuratif Kronik Inardi, Yoke Kurniawan; Widodo, Pujo; Naftali, Zulfikar; Yusmawan, Willy
Medica Hospitalia : Journal of Clinical Medicine Vol. 7 No. 1 (2020): Med Hosp
Publisher : RSUP Dr. Kariadi

Latar belakang : Kehilangan pendengaran merupakan komplikasi otitis media kronik (OMSK) yang paling sering, jenis kehilangan pendengaran yang tersering adalah tuli konduktif, yang disebabkan oleh adanya air bone gap (ABG), ABG pada pasien OMSK mempunyai variasi yang berbeda-beda dan karakter yang khas berdasarkan faktor risiko. Tujuan : Menganalisis hubungan faktor risiko dengan ABG pada penderita OMSK. Metode : Penelitian desain observational analitik retrospektif di RSUP Dr Kariadi Semarang pada bulan September 2018 - Januari 2019. Data diambil dari rekam medis. jumlah sampel ditentukan sebanyak 100. Analisis data dengan uji chi-square. Hasil : Jenis kelamin laki-laki 46 orang, wanita 54 orang, rerata usia 32 tahun. Status osikula, lama sakit, kolesteatom, luas perforasi membran telinga berhubungan terhadap ABG (p <0,05). Kesimpulan : Faktor risiko (status osikula, lama sakit, kolesteatom, perforasi membran timpani) berhubungan dengan air bone gap pada penderita OMSK. Kata kunci : Air bone gap, faktor risiko, otitis media supuratif kronik. Background: Hearing loss is the most frequent complication of chronic otitis media (CSOM), hearing loss is usually caused by conductive deafness caused by the presence of an air bone gap (ABG). ABG in CSOM patients has different variations and distinctive characters based on the factors. Objective: To analyze the relationship of risk factors ABG in CSOM patients. Methods: Observational analytic study with a retrospective observational analytic design at Dr. Kariadi Hospital Semarang in September 2018 - January 2019. Subjects were 100 patients. Data retrieval is done based on medical records about history taking, physical examination and investigation. Data were analyzed by Chi-square test. Results: A total male 46 and female. Avarage age 32 years. Oscular status, duration of illness, cholesteatom, area of ??ear membrane perforation associated with ABG (p <0.05). Conclusion: Risk factors (osicular status, duration of illness, cholesteatom, tympanic membrane perforation) associated with air bone gap in CSOM patients. Keywords: Chronic supurative otitis media, air bone gap, risk factors

Penggunaan Sefepim Untuk Demam Neutropenia Pada AML di RSUP Dr. Kariadi Semarang Septiantoro, Bayu Prio; Perwitasari, Dyah Aryani; Pradipta, Indra
Medica Hospitalia : Journal of Clinical Medicine Vol. 7 No. 1 (2020): Med Hosp
Publisher : RSUP Dr. Kariadi

Latar belakang: Demam neutropenia merupakan salah satu efek samping kemoterapi yang paling serius, karena adanya infeksi dapat berkembang dengan cepat dan dapat mengancam jiwa. Antibiotik yang diindikasikan untuk profilaksis pada pasien demam neutropenia diantaranya adalah sefepim. Penelitian ini bertujuan untuk mengetahui durasi kebutuhan sefepim terhadap perbedaan rejimen kemoterapi AML, serta luaran terapinya di RSUP Dr. Kariadi, Semarang. Metode: Penelitian ini menggunakan rancangan deskriptif dengan pengambilan data secara restrospektif dari bulan Juni 2018 hingga April 2019 di satu ruangan rawat inap RSUP Dr. Kariadi, Semarang. Kriteria inklusi adalah pasien usia 18-64 tahun dengan diagnosa AML yang mengalami demam neutropenia dengan riwayat pernah menjalani kemoterapi, mendapatkan terapi antibiotik sefepim. Kriteria eklusi dalam penelitian ini yaitu pasien yang alergi terhadap sefepim, yang tidak melanjutkan pengobatannya, dengan program cangkok sumsum tulang dan dengan adanya diagnosa sepsis/septik syok sebelum diberikannya sefepim. Hasil: Total sebanyak 15 pasien memenuhi kriteria inklusi. Durasi pemberian sefepim yang paling banyak adalah kelompok dengan pemberian 8-14 hari (46,7%), selanjutnya ?7 hari (33,3%), sedangkan pemberian selama >14 hari tidak ditemukan. Pasien yang meninggal pada penelitian ini sebanyak 3 pasien (20%), dengan 2 pasien diantaranya teridentifikasi mengalami sepsis karena sefepim yang resisten akibat patogen ESBL E. coli, sedangkan satu lainnya tidak diketahui patogen penyebabnya. Kesimpulan: Pasien dengan rejimen intensif rata-rata memerlukan durasi terapi yang lebih lama. Munculnya patogen ESBL khususnya E. coli mempunyai luaran yang jelek dan angka kematian yang lebih tinggi, sehingga kita sarankan untuk menggunakan karbapenem daripada sefepim untuk kondisi ini. Kata kunci: Demam neutropenia, leukemia myeloid akut, sefepim Backgound: Febrile neutropenia is one of the most serious side effects of chemotherapy, because the infection can develop rapidly which can be life-threatening. Cefepime is drug of choice that indicated for prophylaxis in patients with febrile neutropenia. The aim of this study was to determine the duration of the cefepime needs of differences in AML chemotherapy regimens, and the outcomes in Dr. Kariadi General Hospital Center, Semarang. Method: The study used descriptive design with retrospective data collection from June 2018 to April 2019 in an inpatient room at Dr. Kariadi General Hospital Center, Semarang. The inclusion criteria are patients aged 18-64 years old with diagnosis of AML who has febrile neutropenia with a history of having undergone chemotherapy with cefepime prophylaxis. The exclusion criteria in this study were allergy to cefepime, patients who did not continue their treatment, bone marrow transplant programs and diagnosis of sepsis / septic shock before the administration of cefepime. Result: A total of 15 patients met the inclusion criteria. The most duration of cefepime was in the group with 8-14 days (46,7%), then ?7 days (33,3%), whereas> 14 days were not found. The patients who died in this study were 3 patients (20%), with 2 patients identified as having sepsis due to the pathogen ESBL E. coli cefepime resistant, while the other one did not know the causative pathogen. Conclusion: Patients with an intensive regimen require a longer duration therapy. The emergence of ESBL pathogens especially E. coli has poor outcomes and a higher mortality rate, so we recommend using carbapenem rather than cefepime for this condition. Keywords: Febrile neutropenia, acute myeloid leukemia, cefepime

Hubungan Kadar Elektrolit Dengan Petanda Jantung Pada Sindrom Koroner Akut Wijayanti, Emelia; Adipireno, Purwanto
Medica Hospitalia : Journal of Clinical Medicine Vol. 7 No. 1 (2020): Med Hosp
Publisher : RSUP Dr. Kariadi

Pendahuluan: Sindrom koroner akut (SKA) merupakan masalah kardiovaskular utama yang menyebabkan angka perawatan dan kematian yang tinggi. Enzim jantung seperti troponin dan Creatinin Kinase-MB (CKMB) dilepaskan ke peredaran darah dan meningkat pada infark miokard. Elektrolit adalah zat berfungsi untuk menghantarkan listrik. Aktivitas listrik jantung diatur oleh kalsium, kalium dan natrium; kontraksi jantung membutuhkan kalsium, magnesium dan fosfor. Elektrolit berguna sebagai indikator AMI. Penelitian ini bertujuan menganalisis kadar serum elektrolit dengan petanda jantung pada SKA. Metode: Penelitian belah lintang pada 35 pasien SKA pada bulan Desember - Januari 2018. Kadar elektrolit serum diperiksa dengan metode Ion selective electrode (ISE) dan photometric, kadar CKMB diperiksa dengan metode Enzyme-linked immuno assay (ELISA), kadar Troponin I (cTnI) diperiksa dengan metode Enzyme-linked fluorescence assay (ELFA). Uji Korelasi spearman digunakan untuk menganalisis data, signifikan jika p <0.05. Hasil: Terdapat korelasi negatif kuat antara natrium, kalium, clorida, dan magnesium baik dengan CKMB (p 0,000/ 0,000/ 0,001/ 0,014 dan r= -0,631/ -0,634/ -0,557/ -0,412) maupun cTnI (p 0,000/ 0,000/ 0,001/ 0,000 dan r= -0,746/ -0,574/ -0,545/ -0,564). Tidak terdapat korelasi antara kalsium baik dengan CKMB (p= 0,475 dan r= -0,125) maupun cTnI (p= 0,086 dan r= -0,294). Simpulan: Terdapat hubungan negatif antara natrium, kalium, clorida, dan magnesium dengan petanda jantung, tidak terdapat hubungan antara kalsium dengan petanda jantung pada SKA. Temuan ini menunjukkan bahwa rendahnya kadar serum elektrolit pada SKA dapat berarti adanya area infark yang lebih luas. Hasil penelitian ini perlu divalidasi dalam penelitian berskala besar dengan metodologi yang lebih baik dan diharapkan dapat menjadi dasar penelitian lebih lanjut. Kata Kunci: SKA, Elektrolit, CKMB, cTnI Introduction: Acute coronary syndrome (ACS) is a major cardiovascular problem that causes significant morbidity and mortality burden. Cardiac enzymes, such as troponin and Creatinin Kinase-MB (CKMB), are released into the bloodstream and increase in acute myocardial infarction (AMI). Electrolytes involving calcium, potassium and sodium regulate heart electrical activity, while calcium, magnesium and phosphorus regulate its contraction. Electrolytes serve as AMI indicators. This study aims to analyze serum electrolyte levels with cardiovascular markers in ACS. Methods: a coss sectional study of 35 ACS patients was conducted from December to January 2018. Serum electrolyte levels were examined by the Ion selective electrode (ISE) and photometric method, CKMB levels were examined by the enzyme-linked immuno assay (ELISA), Troponin I (cTnI) were examined by the Enzyme-linked fluorescence assay (ELFA) method. Spearman test was perfomed for analyzing data with significant level of <0.05. Results: a strong negative correlation was found between sodium, potassium, chloride, and magnesium and both CKMB (p 0,000 / 0,000 / 0,001 / 0,014 and r = -0,631 / -0,634 / -0,557 / -0,412) and cTnI (p 0,000 / 0,000 / 0.001 / 0,000 and r = -0,746 / -0,574 / -0,545 / -0,564). No correlation was found between calcium and both CKMB (p = 0.475 and r = -0.125) and cTnI (p = 0.086 and r = -0.294). Conclusion: There is significant negative correlation between sodium, potassium, chloride, and magnesium and cardiac markers, there is no correlation between calcium and cardiac markers in ACS. These findings indicate low serum electrolytes values in ACS may have higher area of infarction. These finding need to be validated in large-scale studies with better methodologies and are expected to be the basis for further research. Keywords: ACS, Electrolytes, CKMB, cTnI.

Kejadian Mielosupresi Pada Penderita Kanker Kepala Dan Leher Yang Mendapat Kemoterapi Cisplatin Dan Carboplatin Di RSUP Dr. Kariadi Semarang Dewi, Nila Santia; Yusmawan, Willy; Budiarti, Rery
Medica Hospitalia : Journal of Clinical Medicine Vol. 7 No. 1 (2020): Med Hosp
Publisher : RSUP Dr. Kariadi

Latar belakang : Kemoterapi bersifat sistemik dan non selektif sehingga tidak hanya sel kanker yang mati tetapi juga sel normal. National Comprehensive Cancer Network (NCCN) merekomendasikan Platinum-based sebagai rejimen kemoterapi untuk kanker kepala dan leher terutama Cisplatin dan Carboplatin. Cisplatin dan Carboplatin dapat menyebabkan efek samping mielosupresi. Tujuan : Membuktikan bahwa terdapat perbedaan kejadian mielosupresi pada penderita Kanker Kepala dan Leher (KKL) yang mendapat kemoterapi Cisplatin dan Carboplatin. Metode : Penelitian observasional dengan desain penelitian kohort prospektif di klinik THT-KL, bangsal dan bagian rekam medis instalasi rawat jalan/rawat inap RSUP Dr. Kariadi Semarang. Sampel ditentukan sebanyak 90 orang dan mendapat kemoterapi platinum based dengan salah satu komponen berupa Cisplatin atau Carboplatin sebanyak 3 seri. Analisis data dengan uji Pearson Chi-square dan Fisher’s exact test. Hasil : Subyek penelitian 90 orang, 45 orang mendapatkan Paclitaxel Cisplatin dan 45 orang mendapatkan regimen Paclitaxel Carboplatin. Hasil penelitian ini didapatkan 48,9% pasien stadium IV, histopatologi terbanyak WHO 3 (83,3%). Rerata usia terbanyak 50-59 tahun, dan diagnosis terbanyak pada KNF (66,7%). Secara keseluruhan kemoterapi seri I menunjukkan Carboplatin menyebabkan perubahan kadar hemoglobin (p=1,000) dan leukosit (p=0,292) dengan jumlah subyek lebih banyak dibanding Cisplatin. Sedangkan pada kemoterapi seri III, Carboplatin menyebabkan perubahan kadar hemoglobin (p=<0,023), leukosit (p=0,670), dan trombosit (p=1,000) lebih banyak dibandingkan Cisplatin. Simpulan : Kadar hemoglobin berbeda bermakna pada pasien yang mendapatkan kemoterapi Carboplatin seri III (p<0,023). Kata kunci : Kemoterapi Cisplatin/Carboplatin., kanker kepala dan leher, mielosupresi. Background : Chemotherapy is systemic and non-selective so it often results in not only cancer cells dying but normal cells will also die. The National Comprehensive Cancer Network (NCCN) recommends Platinum-based chemotherapy regimens for head and neck cancer, especially Cisplatin and Carboplatin. Cisplatin and Carboplatin chemotherapy can cause one of the side effects of myelosuppression. Myelosuppression is a decrease in cell production of leukocytes, erythrocytes, and / or platelets. Objective : Proving the difference incidence of myelosuppression in head and neck cancer patients receiving Cisplatin and Carboplatin chemotherapy. Methode : An observational study with a prospective cohort study design in ENT clinic, ward and medical record department of outpatient installation Dr. Kariadi Semarang. Samples was determined by 90 people and received platinum based chemotherapy with one component in the form of Cisplatin or Carboplatin in 3 series. Data analysis by Pearson Chi-square and Fisher’s exact test. Result : The study subjects were 90 people, 45 people received Paclitaxel Cisplatin regimen and 45 people received Paclitaxel Carboplatin regimen. The results of this study found 48.9% of patients in stage IV conditions with the most histopathological types were WHO 3 (83.3%). Overall series I chemotherapy shows Carboplatin causes changes in hemoglobin (p=1,000) and leukocyte (p=0,292) levels with a greater number of subjects than Cisplatin. Where as in series III chemotherapy, Carboplatin causes more changes in hemoglobin (p=<0,023), leukocyte (p=0,670) and platelet (p=1,000) levels than Cisplatin. Conclusions : Hemoglobin level was significantly different in patients who received Carboplatin series III chemotherapy (p<0,023). Keywords : Chemotherapy, head and neck cancer, myelosuppression, Cisplatin, Carboplatin.

Hubungan antara Total Waktu Iskemik pada Transplan Ginjal dengan Lama Perawatan di Rumah Sakit: A Single Center Report Nugroho, Eriawan Agung; Kamar, Muhamad Azwin; Santosa, Ardy; Daniswara, Nanda; Addin, Sofyan Rais
Medica Hospitalia : Journal of Clinical Medicine Vol. 7 No. 1 (2020): Med Hosp
Publisher : RSUP Dr. Kariadi

Latar Belakang : Transplantasi ginjal diakui sebagai kemajuan utama pengobatan modern yang memberikan kehidupan berkualitas tinggi kepada pasien penyakit ginjal stadium akhir (End Stage Renal Disease). Waktu iskemik dingin /Cold Ischemic Time (CIT) telah ditemukan sebagai faktor risiko independen yang penting untuk delay graft function (DGF) pada transplantasi ginjal. Terdapat informasi terbaru bahwa waktu iskemik hangat /Warm Ischemic Time (WIT) yang lama dapat mengurangi kelangsungan hidup graft dalam donor hidup transplantasi ginjal. Tujuan dari penelitian ini adalah untuk mengevaluasi hubungan total ischemik time selama operasi penerima dengan lama rawat inap. Metode : Penelitian ini merupkaan studi observational-cross sectional. Data didapatkan dari catatan medis pasien yang telah menjalani transplantasi ginjal dari Januari 2014 – Desember 2018 du RS Umum dr. Kariadi semarang. Terdapat 28 pasien, 18 diantaranya adalah laki-laki dan 10 adalah wanita. Data total waktu iskemik dibandingkan dengan lamanya rawat inap. Data dianalisa dengan tes Spearman menggunakan software SPSS versi 23. Hasil : Pada studi ini menunjukkan adanya korelasi yang signifikan antara total waktu iskemik dengan lama perawatan di rumah sakit (p<0.001). Akan tetapi, umur donor tidak mempengaruhi total waktu iskemik (p=0.673), tidak signifikan (signifikan jika p<0.005). Simpulan : Adanya hubungan yang signifikan antara total waktu iskemik dengan lama perawatan rumah sakit. Namun, tidak ditemukannya hubungan yang signifikan pada usia donor dan total waktu iskemik. Kata kunci: total waktu iskemik, lama perawatan, transplantasi ginjal Background: Kidney transplantation is recognized as an advanced modern therapeutic modality, providing a better life for patients with end stage renal failure globally. Cold Ischemic Time (CIT) has been found as an important independent risk factor for delay graft function (DGF) in kidney transplantation. DGF also associated with patient’s survival post-operatively. Recent studies suggested that prolonged Warm Ischemic Time (WIT) may decrease graft’s survival in living kidney transplantation donor. This study aimed to evaluate the total ischemic time during recipient surgery and accessed its contribution for hospitalization time in kidney transplantation patients. Methods: This is a descriptive retrospective study. This study was started in 2014 until December 2018, including data from patients’ medical record whom underwent kidney transplantation in Kariadi General Hospital Semarang. Data was collected from 28 patients, including 18 male patients and 10 female patients. The author found a significant correlation between patient’s age and total ischemic time. Total ischemic time also compared with hospitalization time. Data was processed using Spearman test in SPSS software. Results: Based on Spearman test, Total ischemic time was significantly correlated with hospitalization time (p < 0.001). However, donor’s age did not affect prolonged total ischemic time with p = 0.673, which is not significant (significant if p value < 0.05). Conclusion: Total ischemic time has a significant correlation with hospitalization time. In contrary, no significant correlation between donor’s age and prolonged total ischemic time. Key Words: Total ischemic time, hospitalization time, kidney transplantation

Efek Prehabilitation Exercise dengan Resistance Band terhadap Kekuatan Otot Kuadrisep Femoris pada Pasien Total Knee Replacement Ervi, Ervi; Kesoema, Tanti Ajoe; Novriansyah, Robin
Medica Hospitalia : Journal of Clinical Medicine Vol. 7 No. 1 (2020): Med Hosp
Publisher : RSUP Dr. Kariadi

Pendahuluan: Prehabilitation exercise dengan resistance band merupakan latihan penguatan otot yang aman, mudah dilakukan dan dapat dijadikan sebagai home programme pada pasien osteoartritis (OA) yang akan menjalani total knee replacement (TKR). Namun demikian, latihan ini belum lazim dilakukan di Indonesia. Penelitian ini bertujuan untuk mengetahui pengaruh intervensi prehabilitation exercise dengan resistance band terhadap kekuatan otot kuadrisep femoris pada pasien yang menjalani TKR. Metode: Penelitian randomized controlled trial dengan pre and post test. Sebanyak 16 subjek yang memenuhi kriteria dibagi secara acak ke dalam kelompok perlakuan (n=8) dan kontrol (n=8). Kelompok perlakuan mendapatkan prehabilitation exercise dengan resistance band 3x seminggu selama 4 minggu sebelum TKR, sedangkan kelompok kontrol mendapatkan terapi konvensional berupa ergocycle dan TENS (Transcutaneus Electrical Nerve Stimulation) 2x seminggu selama 4 minggu sebelum TKR. Pengukuran kekuatan otot kuadrisep femoris dilakukan 3x yaitu pada 4 minggu dan 1 minggu sebelum TKR, serta 8 minggu setelah TKR menggunakan push-pull dinamometer. Hasil: Kelompok perlakuan menunjukkan peningkatan kekuatan otot kuadrisep femoris yang signifikan pada 4 minggu ke 1 minggu sebelum TKR sebesar 3,00+1,28 (p=0,001). Peningkatan kekuatan otot pada kelompok intervensi juga terlihat pada 4 minggu sebelum ke 8 minggu setelah TKR sebesar 2,38+1,22 (p<0,001). Sebaliknya, kelompok kontrol mengalami penurunan kekuatan otot sebesar -0,88+0,79 (p=0,001) dan -0,88+1,28 (p=0,001) masing-masing pada periode 4 minggu ke 1 minggu sebelum TKR dan 4 minggu sebelum ke 8 minggu setelah TKR. Kesimpulan: Terdapat pengaruh prehabilitaion exercise dengan resistance bands terhadap peningkatan kekuatan otot kuadrisep femoris pada subjek yang menjalani operasai TKR. Prehabilitation exercise dapat digunakan sebagai alternatif latihan yang aman, mudah dilakukan serta dapat dijadikan sebagai home programme pada pasien yang akan menjalani operasi TKR. Kata kunci: Prehabilitation exercise, kekuatan kuadrisep femoris, total knee replacement. Background: Prehabilitation exercises using resistance band is a safe and easy muscle strengthening exercise and can be used as a home programme in OA patients undergoing TKR. This exercise, however, is not commonly used in Indonesia. The this study aims to investigate the effect of prehabilitation exercise using resistance band on quadriceps femoris muscle strength in patients undergoing TKR. Methods: This study is a randomized controlled trial with pre and post-test. A total of 16 subjects who meet criteria were randomly allocated into intervention (n = 8) and control (n = 8) groups. The first group received prehabilitation exercise with resistance bands 3 times a week for 4 weeks before TKR, while the control group received conventional therapies involving ergocycle and TENS (Transcutaneous Electrical Nerve Stimulation) 2 times a week for 4 weeks before TKR. Quadriceps femoris muscle strength was measured three times at 4 weeks and 1 week before TKR, and 8 weeks after TKR using a push-pull dynamometer. Results: The intervention group shows a significant increase in quadriceps femoris muscle strength at 4 weeks to 1 week before TKR (3.00+1.28, p = 0.001). The increased quadriceps femoris muscle strength in the intervention group was also seen at 4 weeks before to 8 weeks after TKR (2,38+1,22, p<0,001). Conversely, the control group experienced a decreased quadriceps femoris muscle strength of -0.88+0.79 (p=0.001) and -0.88+1.28 (p=0.001) respectively in the period of 4 weeks to 1 week before TKR and 4 weeks before to 8 weeks after TKR. Conclusion: There is an effect of prehabilitation exercise with resistance bands on increased quadriceps femoris muscle strength in subjects undergoing TKR. Prehabilitation exercise is safe, easy and can be used as an alternative for home programme. Keywords: Prehabilitation exercise, quadriceps femoris muscle strength, total knee replacement.

Faktor Risiko Infeksi Citomegalovirus Pada Anak Yang Dicurigai Kurang Pendengaran Al Masyrukhi, Nanang Arrahman; Widodo, Pujo; Muyassaroh, Muyassaroh
Medica Hospitalia : Journal of Clinical Medicine Vol. 7 No. 1 (2020): Med Hosp
Publisher : RSUP Dr. Kariadi

Latar belakang : Infeksi Citomegalovirus (CMV) merupakan infeksi kongenital tersering pada bayi dan anak, 1 – 6% bayi lahir hidup. Infeksi CMV menimbulkan kecacatan permanen, salah satunya kurang pendengaran. Tujuan: Mengetahui faktor risiko infeksi CMV pada anak yang dicurigai kurang pendengaran. Metode: Penelitian cross sectional di Clinic Diagnostic RSUP Dr Kariadi Semarang periode Januari-Maret 2019. Sampel ditentukan sebanyak 97 anak dengan kecurigaan kurang pendengaran, yang memenuhi kriteria inklusi, ekslusi. Diagnosis dan derajat kurang pendengaran berdasar pemeriksaan Brainstem Evoked Response Audiometry, Otoacustic Emission dan timpanometri. Infeksi CMV ditentukan dengan pemeriksaan laboratorium. Analisis data menggunakan uji Chi- square. Hasil: Didapatkan 56 (57,7%) anak kurang dengar, kurang pendengaran derajat berat-sangat berat didapatkan pada 48 (85,71%) anak. Infeksi CMV didapatkan pada 59 (60,8%) anak dengan kadar IgG CMV diatas 25UI/ml sebanyak 43(72,88%) anak. Infeksi CMV merupakan faktor resiko kurang pendengaran (p<0,001 RP 16,364 IK 95% 5,9-45,31). Infeksi CMV tidak berpengaruh pada jumlah telinga yang terganggu (p=0,470) dan umur saat dilakukan pemeriksaan BERA (p=0,428). Kadar IgG CMV berpengaruh terhadap kurang pendengaran (p<0,001), namun tidak berpengaruh pada derajat kurang pendengaran (p=0,370) dan umur saat dilakukan pemeriksaan BERA (p=0,516) dengan kadar IgG CMV. Simpulan: Infeksi CMV merupakan faktor resiko kurang pendengaran pada anak yang dicurigai kurang dengar. Kadar IgG CMV berpengaruh terhadap kurang pendengaran. Kata kunci : Infeksi CMV, Faktor risiko, Kurang pendengaran Background : Citomegalovirus (CMV) infection is the most common congenital infection, 1 - 6% born alive infant. CMV infection causes permanent disability, one of which is hearing loss. Objective: To determine CMV infection risk factors in suspected hearing loss children. Method: Cross-sectional study at the Clinic Diagnostic Centre of Dr. Kariadi Hospital Semarang, January-March 2019. Samples were determined as 97 children with suspicion of hearing loss, fulfill inclusion and exclusion criteria. Diagnosis and severity of hearing impairment are based on an examination of Brainstem Evoked Response Audiometry (BERA), Otoacustic Emission (OAE) and Tympanometry. CMV infection is determined by laboratory examination. Data analysis using Chi-square test. Results: Obtained 56 (57.7%) children with hearing loss, 48 (85.71%) children with severe-profound hearing loss. CMV infection was found in 59 (60.8%) children, IgG CMV titers above 25UI / ml found in 43 (72.88%) children. CMV infection is a risk factor for hearing loss (p<0.001 RP 16.364 95% CI 5.9-45.31). CMV infection had no effect on laterality of hearing loss (p=0.470) and age at the BERA examination performed (p=0.428). IgG CMV titers had an effect on hearing loss (p <0.001), but had no effect on severity of hearing loss (p = 0.370) and age at the BERA examination performed (p = 0.516). Conclusion: CMV infection is a hearing loss risk factor in suspected of hearing loss children. IgG CMV titers affect hearing loss. Keywords: CMV infection, risk factor, hearing loss

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Abstract

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Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name Maya Nuriya Widyasari

Contact Email medica.hospitalia@yahoo.com

Phone -

Journal Mail Official medica.hospitalia@yahoo.com

Editorial Address -

Location Kota semarang, Jawa tengah INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
Maya Nuriya Widyasari

Contact Email
medica.hospitalia@yahoo.com

Phone
-

Journal Mail Official
medica.hospitalia@yahoo.com

Editorial Address
-

Location
Kota semarang,

Jawa tengah

INDONESIA