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INDONESIA
Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML)
ISSN : 08544263     EISSN : 24774685     DOI : https://dx.doi.org/10.24293
Core Subject : Health, Science,
Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) is a journal published by “Association of Clinical Pathologist” professional association. This journal displays articles in the Clinical Pathology and Medical Laboratory scope. Clinical Pathology has a couple of subdivisions, namely: Clinical Chemistry, Hematology, Immunology and Serology, Microbiology and Infectious Disease, Hepatology, Cardiovascular, Endocrinology, Blood Transfusion, Nephrology, and Molecular Biology. Scientific articles of these topics, mainly emphasize on the laboratory examinations, pathophysiology, and pathogenesis in a disease.
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Search results for , issue "Vol. 19 No. 1 (2012)" : 1 Documents clear
ANGKA BANDING NETROFIL/LIMFOSIT APENDISITIS AKUT Yanty Tandirogang; Uleng Bahrun; Mutmainnah Mutmainnah
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol. 19 No. 1 (2012)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v19i1.757

Abstract

Acute appendicitis is one of the acute abdominal conditions encountered in almost all hospitals in Indonesia. Acute inflammation of the appendix requiring immediate surgery to prevent complications, so it should takes several particular checking's to support the diagnosis quickly. These are leukocytes count, especially neutrophils and lymphocytes as the sensitive marker of the inflammatory process which belong to the simple laboratory examination and can be used as a diagnostic marker of acute appendicitis as well. The inflammatory immune response can be described of the percentage of neutrophils to the lymphocytes ratio in the circulation. A retrospective study was performed on patients whom suspected for acute appendicitis those undergoing appendectomy from January 2010−May 2011. The data were grouped according to post appendectomy diagnosis and the ratio of neutrophils/lymphocytes (NLR) compared with other parameter. The NLR in each group was compaed by one way ANOVA analyzing. A total of 59 patients were identified: 19 catarrhally, 19 phlegmonous, 10 gangrenous and 11 with perforation. Compared with other markers, NLR is much better in predicting acute appendicitis. NLR increased in all groups (mean>7), specifically on the perforated appendicitis that is greatly increased (mean=12.273). But this was not significantly different NLR from the group (p=0.098). Based on this study it can be concluded, that NLR is the better marker for diagnosis rather than leukocyte and USG. But unfortunately, it can not be used to differentiate the grading in acute appendicitis.

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