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Jurnal Ilmiah Cendekia Eksakta
Published by Universitas Wahid Hasyim Semarang
ISSN : 25285912     EISSN : 25482122     DOI : http://dx.doi.org/10.3194/ce
Core Subject : Health, Science, Agriculture, Engineering,
Agriculture, Biological Sciences & Forestry Chemical Engineering, Chemistry & Bioengineering Computer Science & IT Mechanical Engineering Medicine & Pharmacology
Cendekia Eksakta journal focuses upon aspects of exact sciences: engineering, agriculture, health and pharmacy . The Cendekia Eksakta journal is an research journal and invites contributions of original and novel fundamental research. The journal aims to provide a forum for the presentation of original fundamental research, interpretative reviews and discussion of new developments in chemical engineering. Papers which describe novel theory and its application to practice are welcome, as are those which illustrate the transfer of techniques from other disciplines. Reports of carefully executed experimental work, which is soundly interpreted are also welcome. The overall focus is on original and rigorous research results which have generic significance.
Arjuna Subject : Umum - Umum
Articles 11 Documents
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Search results for , issue "Vol 2, No 2 (2017)" : 11 Documents clear
PENGARUH KONSENTRASI MINYAK KAYU MANIS (Cinnamomum zeylanicum) TERHADAP SIFAT FISIK DAN AKTIVITAS ANTIFUNGI Candida albicans DALAM SEDIAAN EMULGEL Danang Novianto Wibowo
CENDEKIA EKSAKTA Vol 2, No 2 (2017)
Publisher : Universitas Wahid Hasyim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31942/ce.v6i2.5431

Abstract

Minyak kayu manis (Cinnamomum zeylanicum) mengandung sinamaldehid dan eugenol sebagai antifungi Candida albicans untuk mengobati kandidiasis oral. Penelitian ini bertujuan untuk mengetahui pengaruh konsentrasi minyak kayu manis terhadap sifat fisik dan aktivitas antifungi Candida albicans dalam emulgel. Minyak kayu manis (Cinnamomum zeylanicum) diformulasikan dalam bentuk emulgel dengan varian konsentrasi F1 : 1% , F2 : 3% , F3 : 5%, F4 : 7%, F5 : 9%. Formula tersebut diuji sifat fisik dan aktivitas antifungi terhadap Candida albicans menggunakan metode sumuran. Data organoleptis, homogenitas dianalisis secara deskriptif. Viskositas, pH, daya sebar, daya lekat dianalisis dengan korelasi regresi linear. Data diameter daerah hambat dianalisis dengan statistik Kruskall Wallis dilanjutkan Mann Whitney dengan taraf kepercayaan 95%. Kelima formula berwarna putih pekat, bau khas kayu manis, rasa manis khas kayu manis, bentuk semi padat dan homogen. Peningkatan konsentrasi minyak kayu manis meningkatkan pH, viskositas, daya lekat tapi menurunkan daya sebar. Peningkatan konsentrasi minyak kayu manis dalam emulgel mempunyai pengaruh perbedaan yang signifikan terhadap aktivitas antifungi Candida albicans dan minyak kayu manis 5% dalam emulgel mempunyai aktivitas antifungi Candida albicans setara dengan kontrol positif. Nilai diameter daerah hambat yang diperoleh yaitu F1 : 12,71 mm, F2 : 20,06 mm, F3 : 22,11 mm, F4 : 22,52 mm, dan F5 : 24,37 mm.

Page 2 of 2 | Total Record : 11

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