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SCRIPTA SCORE Scientific Medical Journal
Published by Universitas Sumatera Utara
ISSN : 20888686     EISSN : 26860864     DOI : https://doi.org/10.32734/scripta.v1i2
Core Subject : Health,
Medicine & Pharmacology
SCRIPTA SCORE Scientific Medical Journal is a journal aimed to provide a forum for publishing scientific articles in the field of medical or health science. The main focus of SCRIPTA SCORE Scientific Medical Journal is tropical medicine and oncology medicine also the rest of medical fields as the additional focus. To achieve its aim, SCRIPTA SCORE Scientific Medical Journal publishes research articles, review articles, and case reports especially manuscript with a regional or national data to raise the interest of the reader in tropical medicine or oncology medicine as the main focus and the rest of medical fields as the addition focus.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 12 Documents
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Search results for , issue "Vol. 4 No. 2 (2023): SCRIPTA SCORE Scientific Medical Journal" : 12 Documents clear
Potency of Carica papaya Leaf Extract as Thrombocytopenia Therapy for Dengue Hemorrhagic Fever: A Systematic Review of Randomized Control Trials Firmansyah Sabir, Muhammad Farid; Suciangto, William; Rahmani, Muhammad Zaki; Eka Lestari, Anfauziyah; Mubin, Risna Halim
SCRIPTA SCORE Scientific Medical Journal Vol. 4 No. 2 (2023): SCRIPTA SCORE Scientific Medical Journal
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/scripta.v4i2.9541

Abstract

Background: Dengue fever is a common disease in tropical countries. According to the data from the Indonesia Ministry of Health, there were 71.633 Dengue Haemorrhagic Fever (DHF) cases reported in Indonesia, with approximately 459 people dying from the disease. Thrombocytopenia is the most common clinical feature of DHF and often causes serious complications if not treatedproperly. Several studies have analyzed the potency of Carica papaya leaf which has been proven asan effective therapy for thrombocytopenia. Objectives: This systematic review aims to discover the potency of Carica papaya leaf extract as a therapy for thrombocytopenia. Method: Literature was searched by using keywords in accordance with the topic, then filtered according to the inclusion criteria that had been determined according to the PRISMA rules. Publication bias in this reviewwas conducted subjectively using the Revman 5.4 software. Results: From 138 studies, it wasfound that screening was carried out based on inclusion criteria, including a randomized controlled trial study in humans with a population of dengue fever patients and received the intervention of papaya leaf extract so that 6 studies were included in the inclusion study, which was then carried out by qualitative synthesis from the study. Based on the results of the qualitative analysis, it wasfound that there was a faster and more significant improvement in the platelet count between the intervention group compared to the control group in the 6 studies. Conclusion: Carica papaya leaf extract has potential as a thrombocytopenia therapy in dengue fever patients.
On-Pump and Off-Pump Coronary Artery Bypass Grafting As An Open Heart Surgery Procedure In Management Of Coronary Heart Disease Sebayang, Abed Nego Okthara; Abdulgani, Hafil Budianto
SCRIPTA SCORE Scientific Medical Journal Vol. 4 No. 2 (2023): SCRIPTA SCORE Scientific Medical Journal
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/scripta.v4i2.10281

Abstract

Introduction: Coronary heart disease is a condition in which fatty deposits in the heart's coronary arteries change the role and shape of the streets and obstruct blood flow to the heart. Invasive management is known as coronary artery bypass grafting and is divided into two techniques: on-pump coronary artery bypass and off-pump coronary artery bypass. Method: The method used in this study is a systematic review. The literature study conducted by the author is by searching various written sources, whether in the form of books, archives, magazines, articles and journals, or documents that are relevant to the problem being studied. Discussion: The on-pump coronary artery bypass technique is performed using a cardiopulmonary bypass machine which replaces the function of the heart and lungs during the operation process, and the off-pump coronary artery bypass technique is performed without using a cardiopulmonary bypass machine so that the heart keeps beating during the operation. Both of these techniques give equally good results, and their selection depends on the clinical situation of the patient and the cardiac surgeon. Conclusion: Coronary artery bypass grafting is a surgical technique that is currently the choice in managing coronary heart disease patients when treatment and Percutaneous coronary intervention do not provide the best results. There are two techniques for performing CABG, namely on-pump coronary artery bypass and off-pump coronary artery bypass Keyword: Coronary heart disease,  Coronary Artery, On pump coronary artery bypass, off-pump coronary artery bypass   Pendahuluan: Penyakit jantung koroner adalah suatu kondisi di mana timbunan lemak di arteri koroner jantung mengubah peran dan bentuk jalan dan menghalangi aliran darah ke jantung. Penatalaksanaan invasif dikenal sebagai pencangkokan bypass arteri koroner dan dibagi menjadi dua teknik: bypass arteri koroner on-pump dan bypass arteri koroner off-pump. Metode: Metode yang digunakan dalam penelitian ini adalah sistematika review. Studi kepustakaan yang dilakukan penulis adalah dengan menelusuri berbagai sumber tertulis, baik berupa buku, arsip, majalah, artikel dan jurnal, maupun dokumen-dokumen yang relevan dengan masalah yang diteliti. Diskusi: Teknik bypass arteri koroner on-pump dilakukan dengan menggunakan mesin cardiopulmonary bypass yang menggantikan fungsi jantung dan paru-paru selama proses operasi, dan teknik bypass arteri koroner off-pump dilakukan tanpa menggunakan mesin cardiopulmonary bypass sehingga jantung terus berdetak selama operasi. Kedua teknik ini memberikan hasil yang sama baiknya, dan pemilihannya tergantung pada situasi klinis pasien dan ahli bedah jantung. Kesimpulan: Pencangkokan bypass arteri koroner merupakan teknik bedah yang saat ini menjadi pilihan dalam penanganan pasien penyakit jantung koroner ketika pengobatan dan intervensi koroner perkutan tidak memberikan hasil terbaik. Ada dua teknik untuk melakukan CABG, yaitu bypass arteri koroner on-pump dan bypass arteri koroner off-pump Kata Kunci: penyakit jantung koroner, arteri koroner, bedah pintas koroner
Potensi Modifikasi Eksosom Derivat Bone Marrow Mesenchymal Stem Cell (BMMSC) dengan Rabies Viral Glycoprotein (RVG) sebagai Modalitas Mutakhir dalam Penatalaksanaan Penyakit Alzheimer Putri, Safa Nabila; Hidayatullah, Muhammad Rizky; Alfadhanti, Putri Mahirah
SCRIPTA SCORE Scientific Medical Journal Vol. 4 No. 2 (2023): SCRIPTA SCORE Scientific Medical Journal
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/scripta.v4i2.10443

Abstract

Pendahuluan: Penyakit Alzheimer adalah penyakit neurodegeneratif yang menyebabkan gangguan progresif pada fungsi perilaku dan kognitif. Penyakit ini merupakan jenis demensia yang paling umum terjadi dengan prevalensi yang meningkat setiap tahunnya. Patofisiologi kompleks yang dimiliki penyakit ini menyebabkan belum adanya pengobatan yang efektif untuk penyakit Alzheimer. Tinjauan literatur ini bertujuan untuk meninjau lebih lanjut mengenai potensi Rabies Viral Glycoprotein (RVG)-modified exosomes yang berasal dari Bone Marrow Mesenchymal Stem Cell (BMMSC) melalui aktivasi mikroglial otak yang dapat mereduksi Aβ sebagai terapi kuratif terkini pada penyakit Alzheimer. Metode: Literatur dicari menggunakan situs pencari seperti Google Scholar, Science Direct, ResearchGate, dan NCBI. Kriteria inklusi dan eksklusi digunakan untuk mengeliminasi literatur yang tidak berkaitan sehingga diperoleh 24 literatur. Pembahasan: BMMSC dapat meringankan neuropatologi, penurunan memori, dan defisit perilaku. Selain itu, BMMSC yang ditransplantasikan dapat menghambat kematian sel terkait Aβ dan tau. Sementara itu, terjadi peningkatan regulasi ekspresi sitokin antiinflamasi (IL-10 dan IL-4) dan penurunan regulasi sitokin proinflamasi (TNF-a dan IL-1β). Studi ini menunjukkan bahwa penggunaan BMMSC yang diturunkan dari eksosom yang dimodifikasi RVG lebih baik daripada BMMSC yang diturunkan dari eksosom saja untuk meningkatkan fungsi kognitif pada mencit APP/ PS 1. Kesimpulan: RVG-eksosom derivat BMMSC dapat menghambat kematian sel dengan mengurangi akumulasi Aβ dan tau, menyeimbangkan faktor inflamasi otak, serta meningkatkan fungsi memori dan kognitif. RVG-eksosom BMMSC berpotensi sebagai terapi mutakhir penyakit Alzheimer serta penyakit neurogeneratif lainnya. Saran: Dibutuhkan penelitian lebih lanjut terkait mekanisme molekular, dosis, dan efek samping terapi RVG-eksosom derivate BMMSC pada penyakit Alzheimer. Kata Kunci: BMMSC, Defisit Memori, Penyakit Alzheimer, Peptida Amiloid β, Sitokin Inflamasi   Introduction: Alzheimer's disease is a neurodegenerative disease that causes progressive impairment of behavioral and cognitive functions. This disease is the most common type of dementia with an increasing prevalence every year. Due to its complex pathophysiology, there is no effective treatment to date for Alzheimer’s disease. This literature review aims to further review the potential of Rabies Viral Glycoprotein (RVG)-modified exosomes from Bone Marrow Mesenchymal Stem Cells (BMMSC) through microglial activation in the brain which can reduce Aβ as the latest curative therapy in Alzheimer's disease. Method: Literature is searched using search engines such as Google Scholar, Science Direct, ResearchGate, and NCBI. Inclusion and exclusion criteria were used to eliminate unrelated journals so that 24 journals were obtained. Discussion: BMMSC can alleviate neuropathology, memory decline, and behavioral deficits. In addition, transplanted BMMSC could inhibit Aβ and tau-associated cell death. Meanwhile, there is an upregulation of anti-inflammatory cytokines (IL-10 and IL-4) and a downregulation of pro-inflammatory cytokines (TNF-a and IL-1β). The study showed that the use of RVG-modified exosomes derived BMMSC was better than exosomes derived BMMSC to improve cognitive function in APP/PS 1 mice. Conclusion: RVG-modified exosomes derived BMMSC can inhibit cell death by reducing Aβ and tau accumulation, balancing brain inflammatory factors, and improving memory and cognitive function. RVG-modified exosomes derived BMMSC has the potential as an advanced therapy for Alzheimer's disease and other neurogenerative diseases. Suggestion: Further research on the molecular mechanism, dosage, and side effects of RVG-modified exosomes derived BMMSC therapy in Alzheimer’s disease is needed. Keywords: Alzheimer Disease, Amyloid β Peptide, BMMSC, Inflammatory Cytokine, Memory Deficit
Gambaran Tingkat Pengetahuan dan Pemilihan Pengobatan Ketombe pada Mahasiswa Fakultas Kedokteran Universitas Sumatera Utara Sriwulan, Anyelin; Dalimunthe, Dina Arwina; Paramita, Deryne Anggia; Widjaja, Sry Suryani; Samosir, Fauzan Azmi Hasti Habibi
SCRIPTA SCORE Scientific Medical Journal Vol. 4 No. 2 (2023): SCRIPTA SCORE Scientific Medical Journal
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/scripta.v4i2.10495

Abstract

Latar Belakang. Ketombe merupakan gangguan kulit kepala yang ditandai dengan pengelupasan abnormal pada kulit kepala. Ada tiga penyebab utama yang menimbulkan ketombe yaitu jamur Malassezia, sekresi kelenjar sebasea, dan sensitivitas individu. Berbagai macam pengobatan telah banyak dilakukan untuk mengatasi masalah ketombe. Tujuan. Untuk mengetahui tingkat pengetahuan dan pemilihan pengobatan ketombe pada mahasiswa Fakultas Kedokteran Universitas Sumatera Utara Angkatan. Metode. Penelitian ini bersifat deskriptif menggunakan metode pendekatan studi potong-lintang. Sampel penelitian merupakan mahasiswa Fakultas Kedokteran Universitas Sumatera Utara. Pengumpulan data menggunakan kuesioner yang disebarkan secara online melalui Google form dan QR Code. Hasil. Didapatkan mahasiswa memiliki pengetahuan yang baik tentang ketombe (92,1%). Berdasarkan pemilihan pengobatan ketombe, sumber informasi didapatkan melalui media elektronik (84,2%), tempat membeli obat di swalayan/mal (72,6%), cara memilih pengobatan ketombe hanya menggunakan sampo saja (63,7%), faktor pemilihan pengobatan ketombe karena mudah didapatkan (71,1%), alasan pemilihan pengobatan ketombe karena kandungan yang terdapat di dalam sampo sangat bagus (58,4%), bahan yang dipilih dalam pemilihan pengobatan ketombe menggunakan bahan alami dan bahan kimia (51,1%). Kesimpulan. Tingkat Pengetahuan mahasiswa baik tentang ketombe. Berdasarkan pemilihan pengobatan ketombe, sumber informasi yang paling banyak didapatkan responden melalui media elektronik, tempat responden membeli obat paling banyak di swalayan/mal, cara responden dalam memilih pengobatan ketombe paling banyak hanya menggunakan sampo, faktor pemilihan pengobatan ketombe responden paling banyak karena mudah didapatkan, alasan pemilihan pengobatan ketombe responden paling banyak karena kandungan yang terdapat dalam sampo sangat bagus, bahan yang dipilih responden dalam pemilihan pengobatan ketombe paling banyak menggunakan bahan alami dan bahan kimia.
Studi Kasus Home Based Exercise Training Terhadap Kualitas Hidup Pasien Tuberculosis Parudi Rumah Sakit TK II Putri Hijau Alfi, Alfi Syahri; Susyanti, Deni; Pratama, Muchti Yuda
SCRIPTA SCORE Scientific Medical Journal Vol. 4 No. 2 (2023): SCRIPTA SCORE Scientific Medical Journal
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/scripta.v4i2.10506

Abstract

Latar Belakang: Tuberkulosis (TB) Paru merupakan suatu penyakit infeksi menular yang disebabkan bakteri mycobacterium tuberculosis yang dapat menyerang berbagai organ, terutama paru-paru. Penyakit ini bila tidak diobati atau pengobatannya tidak tuntas dapat menimbulkan komplikasi berbahaya hingga kematian. Penderita TB sepanjang perjalanan penyakit akan mengalami beberapa gejala yang mengganggu kehidupannya. Gejala utama TB yaitu batuk dalam jangka waktu yang lama. Selain itu, penderita TB juga mengalami demam yang tidak terlalu tinggi, penurunan nafsu makan, penurunan berat badan, lemah, serta rasa tidak enak (malaise). Berbagai gejala klinis tersebut akan sangat mengganggu penderita TB sehingga mengganggu kualitas hidupnya. Penatalaksanaan secara nonfarmakologis yang diterapkan yaitu latihan endurance di rumah yaitu berjalan kaki secara terstruktur pada pasien di Rumah Sakit Tk II Putri Hijau Medan. Teknik ini dapat mengalami peningkatan kualitas hidup. Tujuan: Penulis bertujuan untuk membantu ketahanan yang dapat memperbaiki efisiensi dan kapasitas sistem transportasi oksigen. Metode: Menggunakan asuhan keperawatan dengan studi kasus. Partisipan adalah Tn. T dan Tn. P dengan Tuberculosis paru yang mengalami penurunan kualitas hidup. Instrumen adalah SOP teknik berjalan kaki secara terstruktur. Hasil: Menunjukan bahwa setelah dilakukan teknik berjalan kaki secara terstruktur dapat meningkatkan kualitas hidupnya. Kesimpulan: Berjalan kaki secara terstruktur dapat mempertahankan keadaan fisik untuk  kualitas hidup, sehingga pasien dapat melakukan aktivitasnya. Kata kunci: Home Based Exercise Training, kualitas hidup, tuberculosis paru   Background: Pulmonary Tuberculosis is a communicable disease caused by mycobacterium tuberculosis that may attack various organs, particularly lungs. If this disease is incompletely treated, it may lead to dangerous complications and to cause death. Patients suffering from pulmonary tuberculosis will show symptoms bothering life. The primary symptom of pulmonary tuberculosis is coughing for long time. In addition to this symptom, the patients also have not too high fever, decreased appetite, weight loss, feeling weak, and malaise. These clinical symptoms will much annoy patients life and their life quality. The non-pharmacological management that can be applied is the training of endurance at home, i.e. training the patients to have a structured walk at Level II Putri Hijau Hospital, Medan. This technique is effective to increase life quality. Objective: this research aims at helping endurance that can improve efficiency and transportation system capacity of oxygen. Methods: case study is employ in this nursing care. The participants taking part in this research are Mr. T and Mr. P who suffer from Pulmonary tuberculosis and experience decreased lige quality. Standart operatimg procedures in having structured walk is used as the instrument. Results: it is showed that structured walk, after applied to the patients, is effective to increase their life quality. Conclusion: Structured Walk is effective to maintain physical condition for better life quality, so that the patients are able to perform their activities.
Penerapan Posisi Miring Kanan dan Miring Kiri (Ambulasi) terhadap Pencegahan Dekubitus pada Pasien Stroke Hemoragik Setiawan, Igo; Susyanti, Deni; Pratama, Muchti Yuda
SCRIPTA SCORE Scientific Medical Journal Vol. 4 No. 2 (2023): SCRIPTA SCORE Scientific Medical Journal
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/scripta.v4i2.10511

Abstract

Left and right oblique positions are ambulation that must be done in patients who have hemorrhagic strokes to prevent decubitus. Decubitus is a complication due to pressure on a squeezed area of ​​the body resulting in pressure sores. This research method is a case study research with a medical-surgical nursing care approach. The study was conducted by two hemorrhagic stroke patients who were given left and right oblique ambulation interventions. The results of the study showed that early left and right oblique ambulation is very useful in preventing decubitus so that it must be applied by nurses to hemorrhagic stroke patients. In addition to preventing decubitus, in patients I and II there was an increase in muscle strength so that it would prevent muscle atrophy. The research recommendation is that left and right oblique ambulation can be applied to hemorrhagic stroke patients, so as to prevent complications such as pressure sores.
Profile of Breast Cancer Patients on Estrogen Receptor Expression in RSUD. Dr. Pirngadi Medan 2018-2019 Laras, Naomi Laksita; Pohan, Pimpin Utama
SCRIPTA SCORE Scientific Medical Journal Vol. 4 No. 2 (2023): SCRIPTA SCORE Scientific Medical Journal
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/scripta.v4i2.10520

Abstract

Background: Breast cancer is a type of cancer with the highest incidence and become the leading cause of death in the world. The incidence rate continues to increase due to various risk factors such as endogenous and exogenous. Immunohistochemical examinations is useful to determine therapy and patient's prognosis. Objectives: This study aims to determine how the profile of breast cancer patients on the expression of estrogen receptor in RSUD. Dr. Pirngadi Medan 2018-2019. Methods: This is descriptive cross-sectional research using random-sampling technique. Data were obtained secondary from medical records of breast cancer patients in hospitals. Dr. Pirngadi Medan 2018-2019. Results: From 250 cases, 71 samples were taken in this study. Of the 71 samples, most of the patients were in the 46-55 year old group with negative ER with 18 people (58.1%), 13 people (56.5%) patients had tumor size T4 with positive ER, most of the patients did not have nodular metastases, distant metastases, family history and use of hormones with negative ER with 26 people (63.4%), 39 people (66.1%), 36 people (60%) and 42 people (62.7%), respectively (66.7%) patients had obese with negative ER, invasive ductal histopathology type with negative ER was mostly found in 41 people (63.1%) and the most histopathological grading was in grade 2 with negative ER with 26 people (57.8%). Conclusion:  Almost all patients based on the characteristics of the majority of breast cancer have negative ER, except patients with T4 tumor size have positive ER. Keywords: breast cancer, estrogen receptor, histopathology type, immunohistochemistry, metastases   Latar Belakang: Kanker payudara merupakan jenis kanker dengan angka kejadian tertinggi dan menjadi penyebab utama kematian di dunia. Angka kejadian tersebut terus meningkat disebabkan oleh berbagai faktor risiko seperti faktor endogen maupun eksogen. Pemeriksaan imunohistokimia seperti reseptor estrogen berguna untuk menentukan terapi dan prognosis pasien. Tujuan: Penelitian ini bertujuan untuk mengetahui bagaimana profil pasien kanker payudara terhadap ekspresi protein reseptor estrogen di RSUD. Dr. Pirngadi Medan Tahun 2018-2019. Metode: Penelitian yang dilakukan adalah penelitian deskriptif observasional menggunakan desain cross sectional dengan teknik pengambilan sampel random sampling. Data diperoleh secara sekunder dari rekam medis pasien kanker payudara di RSUD. Dr. Pirngadi Medan Tahun 2018-2019. Hasil: Dari 250 kasus kanker payudara periode 2018-2019, diambil sampel sebanyak 71 buah rekam medis. Dari 71 sampel, sebagian besar pasien terjadi pada kelompok usia 46-55 tahun dengan ER negatif sebanyak 18 orang (58.1%), sebanyak  13 orang (56.5%) pasien  memiliki ukuran tumor T4 dengan ER positif, sebagian besar pasien tidak mengalami metastasis pembuluh limfe, metastasis jauh, tidak memiliki riwayat keluarga dan penggunaan hormon dengan ER negatif dengan masing-masing sebanyak 26 orang (63.4%), 39 orang (66.1%), 36 orang (60%) dan 42 orang (62.7%), sebanyak 20 orang (66.7%)  pasien memiliki IMT obesitas dengan ER negatif, tipe histopatologi duktal invasif dengan ER negatif paling banyak ditemukan sebanyak 41 orang (63.1%) dan derajat histopatologi terbanyak pada derajat 2 dengan ER negatif sebanyak 26 orang (57.8%). Kesimpulan: Hampir keseluruhan pasien berdasarkan karakteristik kanker payudara mayoritas memiliki ER negatif, kecuali pasien ukuran tumor T4 memiliki ER positif. Kata Kunci: derajat keganasan, gambaran histopatologi, imunohistokimia, kanker payudara, reseptor estrogen
Hubungan Durasi Penggunaan Visual Display Terminal Terhadap Computer Vision Syndrome pada Mahasiswa Fakultas Kedokteran Universitas Sumatera Utara Wijaya, Vincent; Anggraini, Dwi Rita; Lumongga, Fitriani; Syafriani Siregar, Rosmayanti
SCRIPTA SCORE Scientific Medical Journal Vol. 4 No. 2 (2023): SCRIPTA SCORE Scientific Medical Journal
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/scripta.v4i2.10534

Abstract

Pendahuluan. Computer Vision Syndrome merupakan sekumpulan gejala penglihatan yang disebabkan oleh paparan Visual Display Terminal berupa computer, smartphone, dan lain lain dalam jangka waktu yang lama. Mahasiswa selama pembelajaran daring terpapar Visual Display Terminal dalam jangka waktu yang panjang, membuat mereka rentan terkena Computer Vision Syndrome. Tujuan. Penelitian ini bertujuan untuk mengetahui pengaruh durasi penggunaan Visual Display Terminal terhadap Computer Vision Syndrome pada mahasiswa Fakultas Kedokteran Universitas Sumatera Utara. Metode. Penelitian ini merupakan penelitian analitik observasional dengan pendekatan cross-sectional. Penelitian dilakukan di Fakultas Kedokteran Universitas Sumatera Utara pada bulan Agustus 2022. Sampel penelitian yaitu Mahasiswa aktif Fakultas Kedokteran Universitas Sumatera Utara tahun ajaran 2019-2021 diperoleh dengan stratified random sampling. Hasil. Analisis data penelitian menggunakan uji korelasi spearman’s rho rank correlation. Penelitian menunjukkan terdapat adanya hubungan signifikan durasi penggunaan VDT terhadapat CVS (p = 0.03) dengan nilai korelasi yang lemah (d = 0.314). Kesimpulan. Ada hubungan durasi penggunaan lebih dari empat jam secara terus menerus atau pengunaan VDT selama 6 jam terhadap Computer Vision Syndrome, dengan sumber VDT yang paling sering digunakan adalah smartphone.
Karakteristik Kejadian Dermatitis Kontak Iritan pada Karyawan Pencucian Mobil di Kecamatan Medan Selayang Ricardo, Samuel; Zairina, Nova; Ikhsan, Riyadh; Ramadhani, Sumi
SCRIPTA SCORE Scientific Medical Journal Vol. 4 No. 2 (2023): SCRIPTA SCORE Scientific Medical Journal
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/scripta.v4i2.10545

Abstract

ABSTRAK Latar Belakang: Dermatitis kontak akibat kerja merupakan salah satu penyakit kulit akibat kerja yang banyak terjadi. Dermatitis kontak iritan adalah jenis dermatitis kontak yang paling sering terjadi. Dermatitis kontak iritan merupakan peradangan pada kulit akibat efek sitotosik langsung dari bahan kimia atau iritan. Pada pencucian  mobil pekerja akan terpapar dengan bahan iritan pada sabun colek dan detergen. Kondisi ini dapat menurunkan produktivitas karyawan dan memengaruhi kualitas hidup pekerja. Tujuan: Mengetahui karakteristik kejadian dermatitis kontak iritan pada karyawan pencucian mobil di Kecamatan Medan Selayang. Metode: Penelitian dilakukan dengan metode deskriptif dan pendekatan cross sectional study, dengan jumlah sampel 50 orang yang didapatkan dengan teknik purposive sampling. Seluruh sampel kemudian diwawancara dengan menggunakan kuisioner dan hasil dianalisis dengan aplikasi SPSS. Hasil: Didapatkan hasil kejadian tersering pada laki-laki (100%) dengan rentang usia dibawah 30 tahun (88%). Frekuensi tingkat pendidikan responden terbanyak merupakan tamatan Sekolah Menengah Atas (82%). Mayoritas responden memiliki masa kerja dibawah 2 tahun (66%) dan durasi kerja lebih dari 8 jam setiap hari (62%). Tanda dan gejala tersering kulit mengelupas (66%), dengan bagian tubuh dominan terkena adalah bagian telapak tangan (68%). Kesimpulan: Angka kejadian yang tinggi menandakan bahwa kurangnya pemahaman tentang DKI dan kesadaran akan pentingnya penggunaan Alat Pelindung Diri (APD) ketika bekerja. Penelitian selanjutnya juga disarankan menambah variabel penelitian dan juga jumlah sampel yang lebih banyak. Kata kunci: dermatitis kontak iritan, karakteristik, karyawan, pencucian mobil, penyakit akibat kerja   ABSTRACT Background: Occupational contact dermatitis is one of the most common occupational skin diseases. Irritant Contact Dermatitis (ICD) is the most common type of contact dermatitis. Irritant contact dermatitis is inflammation of the skin due to the direct cytotoxic effects of chemicals or irritants. In car washing industry, workers will be exposed to irritants in dab soap and detergent. This condition can reduce employee productivity and affect the quality of life of workers. Objectives: This study aims to determine the characteristics of the incidence of irritant contact dermatitis in car wash employees in Medan Selayang District. Methods: The research was conducted by descriptive method and cross sectional study approach, with a sample of 50 people obtained by purposive sampling technique. All samples were then interviewed using a questionnaire and the results were analyzed using the SPSS application. Results: The results showed that the most common occurrence was in men (100%) with an age range of under 30 years (88%). The frequency of education level of most respondents is high school graduates (82%). The majority of respondents have a working period of less than 2 years (66%) and a work duration of more than 8 hours per day (62%). The most common signs and symptoms were peeling skin (66%), with the dominant body part affected are the palms (68%). Conclusion: The high incidence indicates that there is a lack of understanding of ICD and awareness of the importance of using Personal Protective Equipment (PPE) when working. Further research is also recommended to add research variables and also a larger number of samples. Keywords: car wash, employee, irritant contact dermatitis, occupational disease, profile
Faktor Risiko Usia dan Gejala Klinis terhadap Status Gizi Anak Penyakit Jantung Bawaan di RSUP H. Adam Malik Medan Tahun 2020-2021 Purba, Jefry Junaidi; Tobing, Tina Christina L.
SCRIPTA SCORE Scientific Medical Journal Vol. 4 No. 2 (2023): SCRIPTA SCORE Scientific Medical Journal
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/scripta.v4i2.10563

Abstract

Pendahuluan. Penyakit jantung bawaan (PJB) merupakan kelainan baik pada struktur jantung atau pembuluh darah besar maupun fungsi jantung yang didapat sejak masih berada dalam kandungan. Beberapa faktor risiko diduga dapat mempengaruhi status gizi anak dengan PJB. Tujuan. Menganalisis faktor risiko usia dan gejala klinis terhadap status gizi anak penyakit jantung bawaan. Metode. Penelitian observasional yang bersifat analitik dengan desain cross sectional study. Teknik pengambilan sampel dilakukan dengan cara consecutive sampling. Pengumpulan data dari rekam medis dan dianalisis dengan aplikasi SPSS, baik uji bivariat (Chi-Square test) dan multivariat (Binary logistic regression). Hasil. Terdapat 185 anak dengan PJB. Mayoritas berjenis kelamin laki-laki (94 orang (50,8%)). VSD merupakan jenis PJB terbanyak (80 orang (43,2%)). Mayoritas berusia 0-5 tahun (129 orang (69,7%)). Mayoritas berstatus malnutrisi (98 orang (53%)). Hasil analisis bivariat, tidak ada hubungan usia terhadap status gizi anak dengan PJB (P=0,892) sedangkan gejala klinis berhubungan terhadap status gizi anak dengan PJB (P=0,000). Hasil analisis multivariat, usia tidak dapat dinilai dikarenakan nilai P=0,892 (P>0,25) sedangkan gejala klinis dapat dinilai dikarenakan nilai P=0,000 (P˂0,25) serta berpengaruh signifikan terhadap status gizi anak dengan PJB (P=0,000 dan AOR=3,260 (95% CI=2,128-4,994)). Kesimpulan. Gejala klinis berhubungan serta berpengaruh signifikan terhadap status gizi anak dengan PJB. Kata kunci: Anak, Penyakit Jantung Bawaan, Status Gizi   Background. Congenital Heart Disease (CHD) is an abnormality in the structure of the heart or large blood vessels as well as heart function that is acquired while still in the womb. Several risk factors are suspected to affect the nutritional status of children with CHD. Aim. Analyzing the risk factors of age and clinical symptoms on the nutritional status of children with congenital heart disease. Methods. An analytic observational study with a cross sectional study design. The sampling technique in this study was carried out by consecutive sampling. Data collection from medical records and analyzed by SPSS application, both bivariate test (Chi-Square test) and multivariate (Binary logistic regression). Results. There are 185 children with CHD. The majority were male (94 people (50.8%)). VSD was the most common type of CHD (80 people (43.2%)). The majority were aged 0-5 years (129 people (69.7%)). The majority were malnourished (98 people (53%)). The results of bivariate analysis showed that there was no relationship between age and the nutritional status of children with CHD (P=0.892) while clinical symptoms were related to the nutritional status of children with CHD (P=0.000). The results of multivariate analysis showed that clinical symptoms could be assessed due to the value of P=0.000 (P˂0.25) and had a significant effect on the nutritional status of children with CHD (P=0.000 and AOR=3,260 (95% CI=2,128-4,994)). Conclusion. Clinical symptoms are associated and have a significant effect on the nutritional status of children with CHD.   Keywords: Child, Congenital Heart Disease, Nutritional Status

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