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eJournal Kedokteran Indonesia
Published by Universitas Indonesia
ISSN : 23381426     EISSN : 23386037     DOI : http://doi.org/10.23886/ejki
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health
eJournal Kedokteran Indonesia (eJKI) is a general medical journal, published quadrimester (April, August, December) by Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia. eJKI aims to published the manuscript of students (Bachelor of Medicine (S.Ked), study Program of Medical Profession, magister/specialist, doctoral, and fellow). The journal is a general medical journal that covering all areas of biomedical science, basic medical science, clinical science, medical technology, and medical education. The journal accepts editorial, research article, reviews, evidence-based case report, and also interesting case reports/case study. This work was supported by Faculty of Medicine, Universitas Indonesia.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 12 Documents
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Search results for , issue "Vol 9, No. 2 - Agustus 2021" : 12 Documents clear
Pengaruh Pajanan Auditorik Kombinasi Gelombang Monoton dan Ritmis terhadap Ekspresi Postsynapticdensity-95 Hipokampus Neonatus Ayam Frisca Angreni; DESWATY FURQONITA; AHMAD JUSUF
eJournal Kedokteran Indonesia Vol 9, No. 2 - Agustus 2021
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (987.151 KB) | DOI: 10.23886/ejki.9.64.110

Abstract

Ibu hamil yang terpapar bising akan memengaruhi janin yang dikandungnya bahkan memiliki efek negatif terhadap neurogenesis. Suara dari gelombang ritmis (musik) dapat meningkatkan neurogenesis yang berpengaruh langsung terhadap fungsi memori. Penelitian ini bertujuan untuk mengetahui efek positif gelombang ritmis untuk meredam atau menjadi terapi bagi bagian otak yang sebelumnya mendapat efek negatif gelombang monoton, dilihat dari peningkatan ekspresi densitas optik protein postsynapticdensity-95 dan waktu uji labirin T. Penelitian eksperimental ini dilakukan di laboratorium Developmental Biologi dan Patologi Anatomik Fakultas Kedokteran Universitas Indonesia pada bulan September 2018. Penelitian menggunakan 24 telur ayam yang difertilisasi dan dibagi empat kelompok: kelompok suara ritmis, monoton, gabungan (kombinasi suara monoton dan ritmis), dan kontrol. Telur yang sudah difertilisasi diinkubasi selama 21 hari dan dimiringkan secara otomatis tiap 4 jam. Dilakukan proses candling hari ke-3, ke-5, ke-10 dan ke-15 untuk menilai perkembangan embrio ayam. Hasil penelitian ini, terdapat perbedaan bermakna densitas optik protein postsynapticdensity 95 dan waktu uji labirin T antara kelompok gabungan dengan kelompok ritmis dan monoton, namun tidak terjadi perbedaan bermakna dengan kelompok kontrol. Gelombang ritmis dapat mengurangi efek buruk gelombang monoton dan mengembalikannya menjadi sama dengan normal (kelompok kontrol). Kata kunci: ritmis, monoton, kombinasi suara, memori, postsynapticdensity-95.   Effect of Auditory Exposure combination of Monotonous and Rhythmic Waves on Postsynapticdensity-95 Expression on Neonatal Hippocampus Abstract Pregnant women who are exposed to noise will affect the fetus they contain and even have a negative effect on neurogenesis. Sound from rhythmic waves (music) can increase neurogenesis which directly affects memory function. This study aims to determine the positive effect of rhythmic waves to dampen or become therapy for parts of the brain that previously received the negative effects of monotonous waves, seen from the increase in the expression of the optical density of the postsynapticdensity-95 protein and the labyrint T test time. This experimental study was conducted in the Developmental Biology laboratory and Anatomic Pathology, Faculty of Medicine, University of Indonesia in September 2018. The study used 24 fertilized chicken eggs and divided into four groups: rhythmic, monotonous, combined (a combination of monotonous and rhythmic sounds), and control. Fertilized eggs are incubated for 21 days and automatically tilted every 4 hours. The candling process was carried out on the 3rd, 5th, 10th and 15th days to assess the development of chicken embryos. The results of this study, there was a significant difference in the optical density of the postsynaptic density protein 95 and the time of the T labyrint test between the combined group and the rhythmic and monotonous group, but there was no significant difference with the control group. Rhythmic waves can reduce the bad effects of monotonous waves and return them to normal (control group). Keywords: rhythmic, monotone, sound combination, memory, postsynaptic density-95.
Knowledge, Attitude, and Practice of Mothers on the First 1000 Days of Life Indah Suci Widyahening; Muhammad A Aufa; Muhammad F Alhas; Aji B Widodo; Dewi Friska
eJournal Kedokteran Indonesia Vol 9, No. 2 - Agustus 2021
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (290.545 KB) | DOI: 10.23886/ejki.9.65.129

Abstract

The first 1000 days of life is the window period which critically determines the children’s growth and development and individual’s health afterwards. The knowledge, attitude, and practice (KAP) of pregnant mothers and mothers with children under two years old greatly influence the optimum upbringing of the fetus and children during the period. This study was aimed to evaluate the KAP of mothers about the first 1000 days of life and its associated factors. A cross-sectional study was conducted at a district in Depok city in August 2017. Subjects were purposively recruited to fill the validated KAP questionnaire on the first 1000 days. A total of 110 subjects were recruited, the higher proportion of them have adequate knowledge (42.7%), good attitude ((62.7%), and good practice (61.8%). The mothers’ knowledge was associated with attitude and practice (p<0.001) but the attitude and practice were not associated (p=0.175). Maternal education was the only factor that associated with knowledge (p=0.018) and attitude (p=0.013) while family income was associated with practice (p=0.018). This finding strengthened the importance of the existing community empowerment program such as posyandu in improving the KAP of mothers to achieve better results in the first 1000 days period of their children. Keywords: the first 1000 days of life, knowledge, attitude, practice, nutrition.   Pengetahuan, Sikap dan Perilaku Ibu mengenai 1000 Hari Pertama Abstrak Seribu hari pertama kehidupan (1000 HPK) adalah periode emas yang sangat menentukan tumbuh kembang anak hingga kesehatan individu pada masa selanjutnya. Pengetahuan, sikap dan perilaku (PSP) ibu hamil dan ibu yang mengasuh anak berusia dua tahun ke bawah sangat menentukan asuhan 1000 HPK yang optimal. Penelitian ini bertujuan untuk mengetahui PSP ibu hamil dan ibu dengan anak berusia di bawah 2 tahun mengenai konsep 1000 HPK serta faktor – faktor yang berhubungan dengan ketiga aspek tersebut. Studi potong lintang dilakukan di Kampung Lio, Depok pada Agustus 2017. Ibu hamil dan ibu dengan anak berusia kurang dari 2 tahun direkrut secara purposif untuk mengisi kuesioner PSP tentang 1000 HPK. Sebanyak 110 subjek direkrut, proporsi terbesar subject memiliki tingkat pengetahuan cukup (42,7%), sikap sebagian besar baik (62,7%) dan perilaku sebagian besar juga baik (61,8%). Pengetahuan berhubungan dengan sikap dan perilaku (p<0.001) tetapi sikap dan perilaku tidak berhubungan (p=0,175). Tingkat pendidikan ibu adalah faktor yang berhubungan dengan pengetahuan (p=0,019) dan sikap (p=0,013). Tingkat penghasilan keluarga adalah faktor yang berhubungan dengan perilaku (p=0,018) mengenai 1000 HPK. Hasil ini menguatkan pentingnya posyandu sebagai upaya partisipasi masyarakat dalam meningkatkan PSP ibu untuk mencapai perkembangan anak yang optimal pada periode 1000 HPK. Kata kunci: seribu hari pertama kehidupan, pengetahuan, sikap, perilaku, nutrisi.

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