cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Editor PSR
Contact Email
article@farmasi.ui.ac.id
Phone
+62-21-27608403
Journal Mail Official
psr@farmasi.ui.ac.id
Editorial Address
3rd Floor, A Building, Rumpun Ilmu Kesehatan Kampus Baru UI Depok, 16424, Indonesia
Location
Kota depok,
Jawa barat
INDONESIA
Pharmaceutical Sciences and Research (PSR)
Published by Universitas Indonesia
ISSN : 24072354     EISSN : 24770612     DOI : https://doi.org/10.7454/psr
Core Subject :
Aims Pharmaceutical Sciences and Research (PSR), an international, peer-reviewed, open access, and official journal from Faculty of Pharmacy, Universitas Indonesia, aims to disseminate research results and findings in Pharmaceutical Sciences and Practices. Major area of interest is natural products in drug discovery and development. We also consider other areas related to pharmaceutical sciences and practices. PSR publishes content in English language to promote the sharing of knowledge to international scholars. PSR publish 5 types of articles: 1. Original article 2. Case report 3. Case series 4. Review article 5. Mini review article Scope Researches in Pharmaceutical Sciences and Practices which are covered by PSR are within these subject areas: - Pharmacognosy and Phytochemistry - Pharmaceutical Chemistry - Pharmaceutical Technology - Pharmaceutical Biotechnology - Clinical Pharmacy - Pharmacology-Toxicology - Social and Administrative Pharmacy, including Pharmacoeconomy
Arjuna Subject : -
Articles 11 Documents
 1   2 
Search results for , issue "Vol. 1, No. 1" : 11 Documents clear
Pengaruh Natrium Hialuronat terhadap Penetrasi Kofein Sebagai Antiselulit dalam Sediaan Hidrogel, Hidroalkoholik Gel, dan Emulsi Gel Djajadisastra, Joshita; Dzuhro, Zuraida Syafara; Sutriyo, Sutriyo
Pharmaceutical Sciences and Research Vol. 1, No. 1
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Anticellulite topical gel preparation with caffeine as active ingredient needs a penetration enhancer to reach subcutaneous layer. Sodium hyaluronate (NaHA), the sodium salt of hyaluronic acid, is a hydrophilic polysaccharide derivative polymer. It has ability to enhance percutaneous penetration by loosening the dense of the compact substance stratum corneum. The aim of this research was to observe the effects of NaHA on caffeine penetration as anticellulite active agent in three types of gel preparation: hydrogel, hydroalcoholic gel, and gel emulsion. Each gel type contained caffeine 1,5% and was varied into three formulas. Formula 1 contained HPMC 2% as gel basis; formula 2 contained HPMC 2% and NaHA 0,5%; formula 3 contained NaHA 2% as gel basis. Caffeine penetration properties were analyzed by Franz diffusion cell in vitro test using rat skin as membrane. Percent caffeine penetration of hydrogel formula 1, 2, 3 were 9,41 ± 0,01%; 11,74 ± 0,13%; 16,32 ± 0,03%, respectively. Percent caffeine penetration of hydroalcoholic gel formula 1, 2, 3 were 19,54 ± 0,02%; 22,99 ± 0,23%; 7,42 ± 0,08%, respectively. Percent caffeine penetration of gel emulsion formula 1, 2, 3 were 10,47 ± 0,19%; 13,41 ± 0,12%; 18,42 ± 0,06%, respectively. The result showed that NaHA enhanced the caffeine percutaneous penetration properties in various gel preparations, except hidroalkoholic gel formula 3.

Page 2 of 2 | Total Record : 11

 1   2 

Filter by Year

2004 2014


Reset
Filter By Issues
All Issue Vol. 12, No. 2 Vol. 12, No. 1 Vol. 11, No. 3 Vol. 11, No. 2 Vol. 11, No. 1 Vol. 10, No. 3 Vol. 10, No. 2 Vol. 10, No. 1 Vol. 7, No. 4 Vol. 9, No. 3 Vol. 9, No. 2 Vol. 9, No. 1 Vol. 8, No. 3 Vol. 8, No. 2 Vol. 8, No. 1 Vol. 7, No. 3 Vol. 7, No. 2 Vol. 7, No. 1 Vol. 6, No. 3 Vol. 6, No. 2 Vol. 6, No. 1 Vol. 5, No. 3 Vol. 5, No. 2 Vol. 5, No. 1 Vol. 4, No. 3 Vol. 4, No. 2 Vol. 4, No. 1 Vol. 3, No. 3 Vol. 3, No. 2 Vol. 3, No. 1 Vol. 2, No. 3 Vol. 2, No. 2 Vol. 2, No. 1 Vol. 1, No. 3 Vol. 1, No. 2 Vol. 1, No. 1 More Issue