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Pharmaceutical Sciences and Research (PSR)
Published by Universitas Indonesia
ISSN : 24072354     EISSN : 24770612     DOI : https://doi.org/10.7454/psr
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Aims Pharmaceutical Sciences and Research (PSR), an international, peer-reviewed, open access, and official journal from Faculty of Pharmacy, Universitas Indonesia, aims to disseminate research results and findings in Pharmaceutical Sciences and Practices. Major area of interest is natural products in drug discovery and development. We also consider other areas related to pharmaceutical sciences and practices. PSR publishes content in English language to promote the sharing of knowledge to international scholars. PSR publish 5 types of articles: 1. Original article 2. Case report 3. Case series 4. Review article 5. Mini review article Scope Researches in Pharmaceutical Sciences and Practices which are covered by PSR are within these subject areas: - Pharmacognosy and Phytochemistry - Pharmaceutical Chemistry - Pharmaceutical Technology - Pharmaceutical Biotechnology - Clinical Pharmacy - Pharmacology-Toxicology - Social and Administrative Pharmacy, including Pharmacoeconomy
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Articles 11 Documents
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Search results for , issue "Vol. 8, No. 1" : 11 Documents clear
Drug Repurposing and Dosage Form Development of Anti-COVID-19 Kwok, Kevin
Pharmaceutical Sciences and Research Vol. 8, No. 1
Publisher : UI Scholars Hub

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Abstract

The COVID-19 pandemic has been occurring approximately for more than 1 year. This pandemic has been a health issue that hits all countries in the world caused by the transmission of SARS-CoV-2 virus from one individual to another. The symptoms showed from the infected are fever, shortness of breath, dry cough, headache, and sore throat, among others. The SARS-CoV-2 virus is transmitted through sneezing, coughing, talking, and touching infected objects. Along with this transmission, the SARS-CoV-2 virus will continue to mutate. This mutation becomes an obstacle as well as a challenge to find drugs that can overcome the SARS-CoV-2 virus effectively and safely. The drugs used as anti-COVID-19 are still limited. The steps taken in the process of discovering and developing anti-COVID-19 drugs were through the drug repurposing approach because of the advantages it provides, such as shortens the duration and minimizes the costs required. After several drugs that have potential as anti-COVID-19 were obtained, further research on the development of dosage forms and formulas was carried out to obtain more effective and safer anti-COVID-19 drugs. This review aims to discuss several drugs gained from drug repurposing that have the potential as anti-COVID-19 drugs such as remdesivir, chloroquine/hydroxychloroquine, azithromycin, corticosteroids, and other potential drugs. This review will also discuss several developments of dosage form from the repurposed drugs.

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