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Jurnal Farmasi Sains dan Praktis
Published by Universitas Muhammadiyah Magelang
ISSN : 25499068     EISSN : 25794558     DOI : -
Core Subject : Health, Science,
Immunology & microbiology Medicine & Pharmacology Public Health
Jurnal Farmasi Sains dan Praktis aims to serve the updated scientific knowledge for international researchers in pharmaceutical sciences. Jurnal Farmasi Sains dan Praktis (JFSP) publishes review article, original article, as well as short communication in the all scopes of Pharmaceutical Science such as Pharmaceutics, Biopharmaceutics, Drug Delivery System, Physical Pharmacy, Pharmaceutical Technology, Pharmaceutical Microbiology and Biotechnology, Pharmacology and Toxicology, Pharmacokinetics, Pharmaceutical Chemistry, Pharmaceutical Biology, Community and Clinical Pharmacy, Pharmaceutical Marketing, Alternative Medicines, Pharmaceutical Management, Pharmacoeconomic, Pharmacoepidemiology, Social Pharmacy, Pharmacy Policies.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 6 Documents
 1 
Search results for , issue "vol 12 no 1 (2026)" : 6 Documents clear
THE EFFECT OF EDUCATIONAL VIDEOS AS AN EFFORT TO IMPROVE THERAPY SUCCESS USING THE HEALTH BELIEF MODEL APPROACH: PERCEPTION OF SEVERITY Sundari, Trias Kania; Rajab, Muhammad Andy; Mukaromah, Diyana Latifatul; Afidah, Malikatul; Kamiela, Annisa Azkiya; Sulistyaningrum, Indriyati Hadi
Jurnal Farmasi Sains dan Praktis Vol 12 No 1 (2026)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/hpgsk614

Abstract

Patient compliance with hypertension treatment is often a problem in therapy, so pharmacists and other health workers need to make an effort to improve patients' understanding of the disease and complications that can occur when patients do not take their medication, in order to achieve the clinical outcome of controlled blood pressure. This study aims to determine the effect of educational videos accompanied by the health belief model component of perceived severity on the compliance of hypertensive patients at the Gayamsari Community Health Center in Semarang. The method used in this study was a quasi-experiment using a pre-test and post-test group control conducted on 52 samples of Prolanis Hypertension patients who met the inclusion criteria at the Gayamsari Community Health Center in Semarang City, who were given the MARS (Medication Adherence Rate Scale) questionnaire. Results: From the intervention group that received educational videos accompanied by the health belief model component of perceived severity, the Wilcoxon signed rank test results had a p-value of 0.001, which means that there was a difference in patient compliance scores between the pretest and posttest. Meanwhile, the difference in post-test results between the two groups (control and intervention) also showed significance in the Mann-Whitney U Test with a p-value of 0.000, meaning that educational videos with health belief model components can influence the adherence of hypertensive patients at the Gayamsari Community Health Center in Semarang City. Conclusion: Showing educational videos accompanied by health belief model components to hypertensive patients at the Gayamsari Community Health Center in Semarang City can significantly influence patient compliance with p<0.05.
OPTIMIZATION AND CHARACTERIZATION OF SNAIL MUCUS (Achatina fulica) PEEL-OFF GEL USING FACTORIAL DESIGN METHOD Ramadhani, Dwi Asih; Winanta, Aji; Putra Taufan, Indra
Jurnal Farmasi Sains dan Praktis Vol 12 No 1 (2026)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/v043sx25

Abstract

Indonesia, a tropical country characterized by year-round sun exposure, faces increasing demand for innovative cosmetic formulations with stable and acceptable physicochemical properties. This study aimed to optimize the formulation of a snail mucus peel-off gel mask using a 2² factorial design approach. A peel-off gel snail mask containing 9% snail mucus combined with polyvinyl alcohol (PVA) and sodium carboxymethyl cellulose (CMC-Na) as gelling agents was developed and evaluated. The physical properties of the peel-off gel snail mask were evaluated through organoleptic observations, stickiness tests, spread ability assessments, drying speed measurements, viscosity analysis and pH determination. Subsequently, contour plots were generated and superimposed to delineate the feasible formulation region. Two formulations located within the feasible region were identified: F1 (4.25% CMC-Na and 14.89% PVA) and F2 (4.5% CMC-Na and 14.61% PVA). Rather than representing a single absolute optimum, these formulations exhibited different performance characteristics within the defined optimization constraints. Further investigation into the gelling agents indicated that CMC-Na significantly influenced stickiness and spread ability, while PVA primarily affected viscosity. Drying speed was influenced by the interaction between both polymers.  The factorial design approach successfully defined a formulation space that satisfies predefined physicochemical criteria for peel-off gel masks, providing a rational basis for further formulation refinement.  
COST-EFFECTIVENESS ANALYSIS OF THE USE OF NARCOTIC ANALGESICS IN PATIENTS WITH POST-CAESAREAN SECTION AT A MOTHER AND CHILD HOSPITAL IN PANDEGLANGHILD HOSPITAL IN PANDEGLANG Yusransyah, Yusransyah; Stiani, Sofi Nurmay; Adini, Syilvi Adini; Fauzi, Suci Nurul
Jurnal Farmasi Sains dan Praktis Vol 12 No 1 (2026)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/dafmwq47

Abstract

The majority of patients undergoing cesarean section experience moderate to severe pain. To reduce pain after surgery, therapy can be used in the form of administering narcotic analgesics. The selection of the type of narcotic analgesic affects the level of effectiveness of treatment and the costs required. This study aims to identify the most cost-effective narcotic analgesic therapy in post-cesarean section patients. The study was conducted using a non-experimental method using a descriptive approach, as well as prospective data collection through cost analysis and direct interviews with patients using questionnaires. Cost-effectiveness analysis was conducted using the Cost Effectiveness Analysis (CEA) method using ACER and ICER values. The sample was selected by purposive sampling with a total of 90 patients, consisting of 38 patients in the Fentanyl group and 52 patients in the Fentanyl + Morphine group. The results showed that cost efficiency based on the Faces Pain Rating Scale pain scale produced an ACER value of IDR 1,561 for the Fentanyl group and IDR 1,499 for the Fentanyl + Morphine group. Meanwhile, based on the Visual Analogue Scale (VAS) pain scale, the ACER value for the Fentanyl group was IDR 751 while for the Fentanyl + Morphine group it was IDR 3,404. Based on these findings, the most cost-effective narcotic analgesic therapy according to the Faces Pain Rating Scale assessment is the combination of Fentanyl + Morphine, but based on the Visual Analog Scale assessment, the use of Fentanyl is more cost-effective than the combination of Fentanyl + Morphine.  
A DEMOGRAPHIC FACTORS ASSOCIATED WITH PUBLIC KNOWLEDGE OF STROKE SYMPTOMS AMONG ASIAN POPULATIONS: A NARRATIVE REVIEW  Herayjat, Akbar; Saepudin; Ratna Mafruhah, Okti
Jurnal Farmasi Sains dan Praktis Vol 12 No 1 (2026)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/d5hz6d23

Abstract

Public knowledge of stroke symptoms plays an important role in early recognition and timely treatment, particularly in the pre-hospital phase. In Asian populations, demographic characteristics may influence the level of awareness, but findings across studies have not always been consistent. This article aimed to review the relationship between demographic factors and knowledge of stroke symptoms through a narrative review of previous studies. Ten cross-sectional studies published between 2020 and 2025 were identified through database searches in PubMed and Google Scholar with predefined inclusion criteria. The included studies involved heterogeneous populations, including community-based samples, older adults, healthcare professionals, and outpatients with recurrent stroke or transient ischemic attack. Overall, the findings showed that education was the most consistent factor associated with better stroke knowledge. In contrast, associations with age, information sources, place of residence and socioeconomic status varied across studies and settings. Recognition of core stroke symptoms, particularly those reflected in the FAST concept, tended to be better than knowledge of less consistently identified symptoms and appropriate response patterns. Several studies also showed persistent gaps in prevention knowledge, symptom recognition and emergency response. These findings suggest that stroke awareness in Asian populations remains heterogeneous. Community-based education and improved access to context-appropriate health information are therefore needed to strengthen public understanding of stroke symptoms and support early recognition and response.
THE LEVEL OF KNOWLEDGE AND ATTITUDE OF TRADITIONAL FISHERMEN IN GUAERIA TOWARDS THE RISK OF EAR BAROTRAUMA Nurhalisah; Upik En Masrika, Nur; Fera The; Dewi, Nurmala
Jurnal Farmasi Sains dan Praktis Vol 12 No 1 (2026)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/82maj073

Abstract

Traditional fishermen in remote coastal villages often use simple diving methods with unmonitored dive depth and duration, increasing their risk of ear barotrauma, particularly due to a lack of knowledge and formal training. This study aimed to assess the level of knowledge and attitudes toward ear barotrauma risk among traditional fishermen in Guaeria Village, Jailolo District, West Halmahera Regency, North Maluku Province. This observational study used a cross-sectional design with a total sampling technique, involving all 41 traditional fishermen in the village. Data were collected through structured interviews using a validated questionnaire and analyzed descriptively using SPSS. The results showed that most respondents were aged over 40 years (68.3%), male (100%), had worked for more than 1 year (78%), dove less than 4 days per week (61%), had a normal body mass index (73.2%), and dove for more than 30 minutes per session (70.7%). All respondents (100%) reported a history of barotrauma, with symptoms including ear pain (90.2%), dizziness (90.2%), tinnitus (73.2%), nosebleeds (58.5%), hearing loss (46.3%), and ear bleeding (36.6%). Most fishermen had insufficient knowledge (78.1%) but a sufficient attitude (68.3%) regarding barotrauma risk. In conclusion, traditional fishermen in Guaeria Village show a high prevalence of ear barotrauma symptoms; although their attitude toward barotrauma risk is fairly good, their knowledge remains insufficient, likely due to limited access to information and formal education on diving health risks.
NARRATIVE REVIEW: METHODS FOR MONITORING AND ANALYZING WARFARIN IN BLOOD Yuniarti, Windi Astika; Susilo, Rinto; Sundhani, Elza
Jurnal Farmasi Sains dan Praktis Vol 12 No 1 (2026)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/1vmxea58

Abstract

Warfarin is an oral anticoagulant with a narrow therapeutic index and high interindividual variability in pharmacokinetic and pharmacodynamic responses, requiring careful therapeutic monitoring to maintain efficacy and minimize adverse events. In clinical practice, anticoagulation monitoring is generally performed using the International Normalized Ratio (INR); however, INR values may be influenced by various factors such as drug interactions, dietary vitamin K intake, patient adherence, and genetic polymorphisms, potentially limiting its accuracy as a sole monitoring parameter. Therefore, direct measurement of plasma warfarin concentrations has gained attention as an additional approach to optimize individualized therapy. This narrative review aimed to evaluate and compare analytical methods used for monitoring and analyzing warfarin levels in blood, particularly high-performance liquid chromatography (HPLC) and liquid chromatography–tandem mass spectrometry (LC–MS/MS). Literature sources were obtained from PubMed and selected based on relevance to analytical methods for warfarin quantification published within the last ten years. The reviewed studies demonstrated that LC–MS/MS provides superior sensitivity, specificity, and low detection limits for accurate quantification of warfarin and its metabolites, while HPLC methods remain reliable, accurate, and applicable in routine clinical laboratories with more limited instrumentation. Several studies also reported that plasma warfarin concentration, especially the unbound fraction, may better reflect anticoagulant activity and bleeding risk in certain patient populations compared with INR alone. In conclusion, chromatographic methods are valuable tools for therapeutic drug monitoring of warfarin and may improve individualized anticoagulant therapy when combined with conventional INR monitoring.

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