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Saintika Medika: Jurnal Ilmu Kesehatan dan Kedokteran Keluarga.
Published by Universitas Muhammadiyah Malang
ISSN : 0216759X     EISSN : 2614476     DOI : https://doi.org/10.22219/
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health
Journal of Saintika Medika is a peer-reviewed and open access journal that focuses on promoting medical sciences generated from basic sciences, clinical, and community or public health research to integrate researches in all aspects of human health. This journal publishes original articles, reviews, and also interesting case reports. Brief communications containing short features of medicine, latest developments in diagnostic procedures, treatment, or other health issues that is important for the development of health care system are also acceptable. Letters and commentaries of our published articles are welcome.
Arjuna Subject : Kedokteran - Kedokteran Keluarga
Articles 10 Documents
 1 
Search results for , issue "Vol. 16 No. 2 (2020): December 2020" : 10 Documents clear
The Effectiveness Of Squeeze Of Sambiloto (Andrographis Paniculata) Leaves On The Mortality Of Larvae Aedes Aegypti Graffico Eryza Oldiara; Riandini Aisyah; Safari Wahyu Jatmiko; Devi Usdiana Rosyidah; Rochmadina Suci Bestari
Saintika Medika Vol. 16 No. 2 (2020): December 2020
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/sm.Vol16.SMUMM2.11120

Abstract

Dengue hemorrhagic fever has become a deadly disease since 2013. Dengue fever is a disease caused by dengue virus transmitted to humans through the bite of the Aedes aegypti. Eradication using chemical larvacides still has many disadvantages so that natural larvacides from plants are needed, one of which is larvacide from the squeeze of the sambiloto (Andrographis paniculata) leaves. The squeeze of the sambiloto leaf (Andrographis paniculata) contains flavonoids, alkaloids, tannins and saponins which have natural larvacidal activity. This research aims to determine the killing power of the squeeze of sambiloto (Andrographis paniculata) leaves against Aedes aegypti larvae and determine the most effective concentration as larvicide. This research was experimental laboratory with post test only controlled group design method. There are 600 instar III Aedes aegypti Larvae randomly divided into 6 groups (5%, 10%, 15%, 20%, aquadest and abate). Using 4 repetitions each group was observed every 6 hours for 24 hours. Based on the results of the Kruskal-Wallis non-parametric statistical test obtained p-value = 0,001 which means there are significant differences in larvicidal effects between groups. The concentration of 15% and 20% are the most effective in killing the larvae of Aedes aegypti.
Determinant of Dental Caries in Pre-School Children at TK Permata Hati Bangkalan Lidia Aditama Putri; Diani Octaviyanti Handajani
Saintika Medika Vol. 16 No. 2 (2020): December 2020
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/sm.Vol16.SMUMM2.11253

Abstract

Dental caries is one of the problems that often occurs in pre-school age children (3-6 years) as a result of unfavorable habits of children in maintaining dietary and brushing habits. The purpose of this study was to analyze the factors associated with the occurrence of dental caries in pre-school children. The type of research was observational analytic with cross sectional design. The samples were 81 children by using simple random sampling technique. The analysis of the data used univariate and bivariate using the Chi Square statistical test. The results showed that the factors associated with the occurrence of dental caries in pre-school children were the habit of eating cariogenic food (p = <0.001), the habit of drinking milk with a dot bottle (p = <0.001), the frequency of brushing (p = 0.004 ), and brushing time (<0.001). From 81 children which had been observed, 49 (60.5%) had dental caries, while 32 (39.5%) did not have caries. Therefore, serious efforts were needed to prevent dental caries in pre-school children by increasing the knowledge of mothers and pre-school children about proper and correct brushing procedures and encouraging mothers to have regular dental check-ups every 6 months, so that the problems related to oral health can be detected early.
Commersial Drug Patch Test for Identifying Etiologic Drug of Adverse Cutaneous Drug Reaction Vidya Hana Dwi Ayuningtyas; Herwinda Brahmanti
Saintika Medika Vol. 16 No. 2 (2020): December 2020
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/sm.Vol16.SMUMM2.11266

Abstract

Adverse cutaneous drug reaction (ACDR) is a challenging condition for clinician, especially in determining the etiologic drug. Identification of etiologic drug become more difficult when the patient consume multiple drugs at once. As cellular immunity response is the main mechanism underlying exanthematous eruption, the most common type of ACDR, patch test rise as the reliable diagnostic modality to find the etiologic drug as this test represent the same mechanism as ACDR. In this paper, we reported commercial drug patch test application testing Griseofulvin, Amoxicillin, Ibuprofen, Aspirin and Clindamycin in 37 years old woman with history of drug induced-exfoliative dermatitis six months ago. Patch test technique involves patient preparations, test drug formulation, test drug patching and evaluation on day 2, 4 and 7. Before doing patch test, patient must not take any corticosteroid or immunosuppressant drug within one month ahead. The suspected drug consist of Griseofulvin, Ibuprofen and Clindamycin. Amoxicillin was chosen as the cross reacted drug for Griseofulvin while Aspirin was chosen as the cross reacted drug of Ibuprofen. All tested drugs were formulated as homogenous powder with 10% concentration and mixed with white paraffin. The formulated drug was patched to patient’s back using 7 mm diameter finn chamber. The evaluation result showed positive reaction towards Griseofulvin and weak positive reaction towards Amoxicillin
The Risk for Obstructive Sleep Apnea and Cognitive Function of High School Student Ferrany Thifla Aghni Brilliana; Nurfitri - Bustamam; Cut - Fauziah
Saintika Medika Vol. 16 No. 2 (2020): December 2020
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/sm.Vol16.SMUMM2.11340

Abstract

Obstructive sleep apnea (OSA) is a common sleep disorder characterized by recurrent partial and/or total upper airway obstruction during sleep resulting in hypoxemia and arousal. One of the risk factors for OSA is obesity which its prevalence increased in Indonesia. OSA has a negative effect on cognitive function broadly. This study was aimed to determine the association between risk for OSA and cognitive function in high school students with obesity at Sulthon Aulia Boarding School, Bekasi. The study used a cross-sectional design and a simple random sampling technique. Data were taken using the Berlin Questionnaire and the Montreal Cognitive Assessment Indonesia version (MoCA-Ina) Questionnaire. The sample size is 47 subjects with inclusion criteria had overweight or obese body mass index (BMI) and were willing to be the research subjects. Subjects with a history of head injury, smoking, drinking alcohol, and taking sedative drugs were excluded from the study.  There were differences in BMI and neck circumference between high-risk subjects for OSA and low-risk subjects for OSA. The risk level for OSA was significantly associated with cognitive function (p = 0.001; OR =12.727).  High-risk subjects for OSA are recommended to lose weight and perform a polysomnographic evaluation.
Kersen Leaf (Muntingia Calabura L.) Extract Prevents Gastric Damage of Wistar Rats Exposed to 40% Ethanol Dyah Ayuning Permatasari; Arum Kartikadewi; Afiana Rohmani; Noor Yazid
Saintika Medika Vol. 16 No. 2 (2020): December 2020
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/sm.Vol16.SMUMM2.11368

Abstract

Latar Belakang: Mengurangi stres akibat oksidatif dan mengurangi risiko mukosa lambung. Daun Kersen dikenal sebagai antioksidan. Penelitian ini bertujuan untuk mempelajari efek ekstrak daun Kersen untuk mencegah kerusakan lambung pada tikus Wistar yang diinduksi alkohol.Metode : Penelitian ini adalah eksperimental laboratorium dengan menggunakan desain kelompok Post test saja. Sampel terdiri dari 24 tikus wistar jantan yang dibagi menjadi 4 kelompok, yaitu K-diberikan plasebo aquadest 1,8ml / 200g / hari, K + diberi etanol 40% dosis 1,8ml / 200g /, P1 dan P2 adalah tikus yang diinduksi dengan alkohol 40% dan diberikan dengan ekstrak daun Kersen (500 mg / kg berat badan untuk P1 dan 750 mg / kg berat badan untuk P2), 60 menit setelah pemberian alkohol. Skor Kerusakan lambung berdasarkan Skor Barthel-Manja. Perbedaan rata-rata pada tingkat kerusakan mukosa lambung antara kelompok yang dianalisis dengan One Way ANOVA Test dan Post hoc Lsd Test.Hasil : Rata-rata skor kerusakan lambung adalah; K- = 0,44, K + = 1,76, P1 = 0,76 dan P2 = 0,44 (p <0,001). Perbedaan derajat kerusakan mukosa lambung pada K +, P1, P2 dibandingkan dengan masing-masing K- (ρ: <0,001); (ρ: 0,143); (ρ: 1.000).Kesimpulan : Pemberian ekstrak daun Kersen dengan dosis 500mg / Kg dan 750mg / Kg mampu mencegah kerusakan mukosa lambung yang diinduksi oleh etanol 40%.
Effectivity Test of Tobacco Leaf (nicotiana tabacum l.) 96% Ethanol Extract on Culex Quinquefasciatus Larvae Mortality Ahmad Rosid Nasrulloh Arifqi; Devi Usdiana Rosyidah; Listyana Masyita Dewi; E. M. Sutrisna
Saintika Medika Vol. 16 No. 2 (2020): December 2020
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/sm.Vol16.SMUMM2.11403

Abstract

Culex quinquefasciatus acts as a vector for Filariasis disease. The transmission of this disease can be prevented by cutting the life cycle of these mosquitoes at the larvae phase. Tobacco leaf contains an alkaloid, flavonoid, essential oil, saponin, and tannin which can kill Culex quinquefasciatus larvae. This study is a laboratory experiment with a post-test only controlled group design. This study used the larvae of Culex quinquefasciatus third-instar larvae. Six hundreds larvae were divided into 6 groups and 4 repetitions (each consisted of 25 larvae), i.e. negative control (distilled water + CMC), tobacco leaf ethanol extract (EEDT) with 0.025%; 0.05%; 0.075% and 0.1% doses and positive control (temephos). The number of dead larvae was counted at 6, 12, 18, and 24 hours after treatment. The results of the Kruskal-Wallis test showed p-value = 0.000, followed by the Mann-Whitney Post-hoc test, which resulted in all four doses of EEDT significantly differed compared to the negative control. However, 0.1% concentration was insignificantly different than the positive control. This showed that the ethanol extract of Nicotiana tabacum L. was effective in killing Culex quinquefasciatus larvae and EEDT with 0.1% concentration had the same potential as temephos as a larvicide.  
The Relationship Between Diagnosis Of Acute Appendicitis And Leukocytosis Laboratory Results In The General Hospital Of Muhammadiyah Malang Period 2016-2017 Mochamad Aleq Sander
Saintika Medika Vol. 16 No. 2 (2020): December 2020
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/sm.Vol16.SMUMM2.14964

Abstract

In making the diagnosis in patients with symptoms that are not typical, the doctor needs to do a supporting examination, one of which is an examination of leukocytes count. This examination is very supportive for the diagnosis of acute appendicitis, can be done at the public health center, the price is affordable, and simple. The number of leukocytes in acute appendicitis generally increases to around 10,000-18,000 µL. The experience at UMM General Hospital also varies greatly in the number of leukocytes in patients with acute appendicitis. We often encounter patients with acute appendicitis who have increased leukocytes (leukocytosis), but it is not uncommon to see patients with normal leukocytes. This type of research was analytic observational with cross-sectional. Samples are all patients with a diagnosis of acute appendicitis that fulfills the criteria of inclusion in inpatient installation of UMM General Hospital. Free variables: leukocytosis and dependent variable: acute appendicitis. Data was analyzed using categorical comparative table 2x2 chi square, with confidence interval of 95% using SPSS release 20. The results showed a significant correlation between appendicitis and leukocytosis with sig = 0.000. The conclusion shows that there is a relationship between the diagnosis of acute appendicitis and the results of leukocytosis laboratory at UMM General Hospital Malang.
Analysing Factor Affecting Measles Immunization Gita Sekar Prihanti; Tita Wisata; Rofwiun Rofwiun; Mariyah Giptiyah; Tira Anna Kasih; Nasrul Nasehati; Ulil Amri Pramadani; Mochamad Bilal
Saintika Medika Vol. 16 No. 2 (2020): December 2020
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/sm.Vol16.SMUMM2.15028

Abstract

Background: Immunization development program is one of the priority issues in national health that an effort to reduce the morbidity and mortality on children. East Java is one of province the number of incomplete children immunization that has reach 21% and children did not get immunization has reach 2.08 %. Objective: Knowing factors mother age, tradition, education, knowledge, income, work, attitude, siblings, family support, and health facilities has affect to the completeness of measles immunization in X public health center at Y city, Methods of the Research: This study used analytic observational with cross sectional design. Data analysis used Chi-Square test and logistic regression. The study involving 218 respondent consist of 114 mothers with children who have measles immunization and 104 mothers with children who do not immunize measles. Result and Discussion: There was a correlation between tradition (p = 0.020, OR = 4,428, CI = 95%), attitude (p = 0.00, OR = 5,616, CI = 95%), and maternal education (p = 0.000, OR = 0,236, CI = 95 %) on measles immunization with R value 0,234 in the amount of 23,4%. Conclusion:  There exist a need of health education and counseling for improving maternal education, tradition, and attitude. Support from family, public health center and community was necessary to increase completeness of children immunization especially measles vaccine
The Effect Of Moringa Leaf (Moringa Oleifera Lam) And Vitamin C Combination Extract In Improving Anemia Indicators Deficiency Of White Rice Iron Male Diet Low Rice Iron Diah Hermayanti; Hawin Nurdiana; Wahyu Setiawan; Refa Maulana Azhar
Saintika Medika Vol. 16 No. 2 (2020): December 2020
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/sm.Vol16.SMUMM2.15029

Abstract

Iron deficiency anemia is still a major health problem in developing countries. Therapy with iron preparations often causes undesirable side effects. Moringa leaf extract which is rich in iron can be used as an alternative therapy in iron deficiency, and combination with vitamin C can increase the effectiveness of iron absorption in the gastrointestinal tract. determine the effect of the combination of Moringa oleifera lam. Extract and vitamin C on the indicator of iron deficiency anemia in white rats (Rattus Novergicus Strain Wistar) who were given a diet low in iron aking rice. True experimental research design using post test only control group design. The object of this study was male white rats (Rattus novergicus Strain wistar) induced by a low-iron rice diet. The study was divided into negative control group, positive control group, the treatment group with Moringa leaf extract dose of 400 mg / kg body weight, 800 mg / kg body weight, 1,600 mg / kg body weight. The treatment group was given vitamin C in a dose of 40 mg. Results and Discussion One wayAnova test, hemoglobin sig. 0,000 (p <0.05), MCV sig 0.27 (p> 0.05), MCH sig 0.16 (p> 0.05), serum iron sig. 0,000 (p <0.05), transferrin saturation sig. 0.006 (p <0.05), and TIBC sig 0.68 (p> 0.05). Pearson correlation for hemoglobin 0.746 (sig.0,000), and linear regression with R2 0.557 (sig.0,000); for serum iron 0.742 (sig.0,000) with R2 0.551 (sig.0,000). There was an increase in hemoglobin and serum iron levels in the treatment group.
Sensitivity, Specificity, and Diagnosting Value of Bahrudin’s Score in Diagnosing Stroke Compared to CT-Scan Mochamad Bahrudin; Salsabilla Rihadatul Aisy
Saintika Medika Vol. 16 No. 2 (2020): December 2020
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/sm.Vol16.SMUMM2.15044

Abstract

Stroke is an emergency situation leading to disability and death. Fast, precise, and easy diagnostic tools is needed as an substitute for CT-Scan, especially when CT-Scan is not available. This study is conducted to determined sensitivity, specificity, and diagnostic value of Bahrudin’s Score compared to CT-Scan in diagnosing bleeding or infarct stroke. This research was conducted at Gambiran Kediri Hospital and Lamongan Muhammadiyah Hospital using 89 patients as samples. It was analyzed to define sensitivity, specificity, positive predictive value, negative predictive value,  positive likelihood ratio, negative likelihood ratio, accuracy, reciever operating characteristic curve, and area under curve in order to define diagnostic value of Bahrudin’s Score. Infarct stroke was found in 54%, 58% happened in male and 96,6% found in age over 40.   Sensitivity of Bahrudin’s Score is 0.868, specificity 0.860, positive predictive value os 0.825, negative predictive value is 0.896, positive likelihood ratio is 6.600, negative likelihood ratio is 0.153, accuracy 0.864, and AUC 86.4%. It is determined that Bahrudin’s score with AUC 86.4% is feasible to replace CT-Scan when it is not available.

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