cover
Contact Name
Ayyub Harly Nurung
Contact Email
ayyub.harlynurung@umi.ac.id
Phone
+6282328980617
Journal Mail Official
jmic.sci@umi.ac.id
Editorial Address
Editor's Address: 3rd Floor Laboratory Faculty of Pharmacy, 2nd Campus of UMI: Jl. Urip Sumoharjo km. 5 , Makassar, South Sulawesi, Indonesia
Location
Kota makassar,
Sulawesi selatan
INDONESIA
Journal Microbiology Science
ISSN : 2808392X     EISSN : 28083911     DOI : https://doi.org/10.56711/jms
Core Subject : Health, Science,
Journal Microbiology Sciences (J. Mic. Sciences) receives writing in the form of research results, scientific studies and brief descriptions relating to Microbiology, such as Molecular and Microbial Epidemiology Clinical Microbiology Medical Microbiology Pharmaceutical Biotechnology and others related to Microbiology Sciencee
Articles 15 Documents
Search results for , issue "Vol 4, No 2 (2024)" : 15 Documents clear
Antibacterial Activity of Endophytic Fungi Isolate from Bidara Plant (Ziziphus mauritiana Lam.) Against Bacteria That Cause Digestive Infections by Agar Diffusion Method Rahmadhani, Paramita; Fitriana, Fitriana; Nurung, Ayyub Harly
Journal Microbiology Science Vol 4, No 2 (2024)
Publisher : Fakultas Farmasi, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jms.v4i2.1145

Abstract

Isolates of endophytic fungi coded IFAZ-6 derived from bidara plants (Ziziphus mauritiana Lam) has antibacterial abilities. This study determine whether those isolates has antibacterial activity against bacteria Escherichia coli. Isolates of endophytic fungi were purified and fermented for 21 days and the fermentation results were extracted using ethyl acetate solvent. The ethyl acetate extract obtained was carried out with a minimum inhibitory concentration (MIC) and a minimum bactericidal concentration (MBC) as well as activity tests with the agar diffusion method. From the test results, statistical tests were carried out, the highest concentration IFAZ-6 isolate extracts that has highest inhibitory zone was 300,000 ppm in E. coli bacteria but only significantly different to 200.000 ppm.
Antibacterial Activity of Ethanol Extract Red (Jatropha gossypifolia) Leaves Against Bacterial Skin Infections by Agar Diffusion Imada, Nurul
Journal Microbiology Science Vol 4, No 2 (2024)
Publisher : Fakultas Farmasi, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jms.v4i2.1125

Abstract

Red Jatropha gossypifolia plant is a type of Jatropha with purplish red leaves which the chemical compounds are found are calcium oxalate, jatroidene, interquinones, flavonoids, flobatin and phenolics, and these compounds can be used as an anticoagulant, anti-inflammatory, analgesic and antibacterial. The aim of this research is to determine the antibacterial activity of red Jatropha leaves ethanol extract against bacteria causes skin infections by Agar Diffusion. The result of screening antibacterial test of red Jatropha leaves ethanol extract with a concentration of 0,1% active against bacteria Staphylococcus aureus, Staphylococcus epidermidis, Propionibacterium acne and Pseudomonas aeruginosa. The result of analysis Minimum Inhibitor Concentration (MIC) and Minimum Bactericidal Concentration (MBC) ethanol extract obtained MIC value = 0.1% to bacteria acid, MBC value = 0.05% to bacteria acid, and the result of antibacterial activity of ethanol extract obtained the largest inhibitory zone diameter at a concentration of 12.8% was 13.577 mm against Staphylococcus aureus.
Antibacterial Potential of Ethanol Extract from White Pidada (Sonneratia alba) Leaves Against Gastrointestinal Pathogens Rudiah, Sukhriatun
Journal Microbiology Science Vol 4, No 2 (2024)
Publisher : Fakultas Farmasi, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jms.v4i2.1123

Abstract

The antibacterial properties of the ethanol extract of White Pidada leaves (Sonneratia alba), a mangrove plant rich in bioactive compounds such as phenols, flavonoids, steroids, saponins, triterpenoids, tannins, and alkaloids, were evaluated in this study. The research focused on determining the Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) against gastrointestinal infection-causing bacteria, including Salmonella typhii, Shigella dysenteriae, Escherichia coli, and Vibrio cholerae. The MIC results showed effective inhibition at concentrations as low as 0.025% for Shigella dysenteriae, 0.05% for Salmonella typhii and Vibrio cholerae, and 0.5% for Escherichia coli. The MBC analysis indicated bactericidal activity at higher concentrations, with significant effects observed at 1% for Salmonella typhii, 0.05% for Shigella dysenteriae and Vibrio cholerae, and 0.1% for Escherichia coli. Agar diffusion tests confirmed that increasing extract concentrations correlated positively with the inhibition zone diameter, highlighting the potential of White Pidada leaves as a natural antibacterial agent.
Antibacterial Activity of N-Hexan and Ethyl Acetate Fractions of Gaharu Leaves (Aquilaria malaccensis) Against Bacteria Causing Skin Infection Sompa, Putri Tenri; Herwin, Herwin; Fitriana, Fitriana
Journal Microbiology Science Vol 4, No 2 (2024)
Publisher : Fakultas Farmasi, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jms.v4i2.1147

Abstract

Gaharu (Aquilaria malaccensis) leaves are plants that are useful in the treatment of infectious diseases. This study aims to obtain n-hexane and ethyl acetate fractions of Gaharu leaves that have antibacterial activity against skin infection bacteria by agar diffusion. The results of antibacterial activity screening of the n-hexane fraction and ethyl acetate fraction at a concentration of 0.1% is bacteriostatic. The test results of Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) using concentrations of 0.1%, 0.2%, 0.4%, 0.8%, 1.6%, 3.2%, 6.4% and 12.8% obtained MIC value of n-hexane fraction at 0.2% against P. acnes, P. aeurogynes bacteria and 0.4% against S. aureus, S. epidermidis bacteria, MIC value of ethyl acetate fraction was 0.2% against P. aeuroginosa, S. aureus bacteria and 0.4% against P. acnes, S. epidermidis bacteria. MBC value of n-hexan fraction was 0.4% against P. acnes, P. aeuroginosa bacteria, 0.8% against S. aureus bacteria, 1.6% against S. epidermidis bacteria, MBC value of ethyl acetate fraction was 0.4% against P. acnes, P. aeuroginosa, S. aureus bacteria, 0.8% against S. epidermidis bacteria. The results of the antibacterial activity using concentrations of 1.56%, 3.12%, 6.25%, 12.5% and 25% obtained the largest inhibition zone diameter of the n-hexane fraction was 13,99 mm and the ethyl acetate fraction was 27,68 mm against S. epidermidis bacteria at a concentration of 25%. Based on the results, it can be concluded that the antibacterial activity of the ethyl acetate fraction against all test bacteria is stronger than the n-hexane fraction
Antibacterial Evaluation of Agarwood (Aquilaria malaccensis) Leaf Ethanol Extract Against Pathogenic Bacteria Using TLC-Bioautography Marsaoly, Rivaldy
Journal Microbiology Science Vol 4, No 2 (2024)
Publisher : Fakultas Farmasi, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jms.v4i2.1128

Abstract

Pathogenic bacteria are microorganisms that live in the human body that cause disease, such as the bacteria bacillus subtilis, Pseudomonas aeruginosa, and Eschericia coli. compounds such as flavanoid compounds, alcolloids, saponins, tannins, and terpenoids that has antibacterial properties The purpose of this research was to determine the antibacterial activity of agarwood leaf ethanol extract (Aquilaria malaccensis) against pathogenic bacteria by TLC - bioautography. The results shown that agarwood leaf ethanol extract (Aquilaria malaccensis) has potential as antibacterial against, Pseudomonas aeruginosa, Bacillus subtilis, and Escherichia coli, with three active spots identified in the bioautogram profiles an Rf value of 0.20 demonstrated inhibition against Bacillus subtilis, Pseudomonas aeruginosa, and Escherichia coli Additionally, Rf values of 0.50 and 0.36 exhibited inhibitory effects against Pseudomonas aeruginosa and Escherichia coli, highlighting the potential of agarwood leaf ethanol extract in combating pathogenic bacteria

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