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Al Makki Health Informatics Journal
Published by Al-Makki Publisher
ISSN : 30256518     EISSN : 30250501     DOI : -
Core Subject : Health,
Dentistry Health Professions Nursing Public Health Veterinary
l Makki Health Informatics Journal is an open-access scientific peer-review journal publishing. The Al Makki Health Informatics Journal focuses on exchanging information relating to intelligent computing and health informatics applied in industry, hospitals, government, and universities. All articles should include a validation of the idea presented, e.g. through case studies, experiments, or systematic comparisons with other approaches already in practice. Two types of papers are accepted: (1) A short paper that discusses a single contribution to a specific new trend or a new idea, and; (2) A long paper that provides a survey of a specific research trend using a systematic literature review (SLR) method, as well as a traditional review method. Topics of interest include, but are not limited to: Electronic health record E-Health Information Medical Image Processing & Techniques Data Mining in Healthcare Bioinformatics & Biostatistics Mobile applications for patient care Medical Image Processing & Techniques Hospital information systems Document handling systems Electronic medical record systems Standardization, and systems integration ICT in health promotion programmes e-health Guidelines and protocols E-learning & education in healthcare Telemedicine Software- Portals-Devices & Telehealth Public health & consumer informatics Data Mining & Knowledge Discovery in Medicine ICT for Patient empowerment ICT for Patient safety Medical Databanks-Databases & Knowledge Bases Healthcare Quality assurance Nursing Informatics Evaluation & Technology Assessment Home-based eHealth Health Management Issues Health Research Health Economics Issues Statistical Method for Computer Medical Decision Support Systems Medical Informatics or medicine in general Organizational, economic, social, clinical impact, ethical and cost-benefit aspects of IT applications in health care.
Arjuna Subject : Profesi Kesehatan - Terminologi Medis
Articles 10 Documents
 1 
Search results for , issue "Vol. 3 No. 2 (2025): Al Makki Health Informatics Journal" : 10 Documents clear
The Role of the Four Pillars in Heart Failure with Reduced Ejection Fraction (HFrEF) and Heart Failure with Preserved Ejection Fraction (HFpEF): How Different? Wili Mahendra, Dentino
Al Makki Health Informatics Journal Vol. 3 No. 2 (2025): Al Makki Health Informatics Journal
Publisher : Al Makki Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57185/hij.v3i2.49

Abstract

Heart failure (HF) remains a major clinical challenge, with two main phenotypes: heart failure with reduced ejection fraction (HFrEF) and heart failure with preserved ejection fraction (HFpEF). These conditions exhibit distinct pathophysiology, clinical manifestations, and therapeutic responses, requiring distinct management approaches. The four pillars of HFrEF therapy—renin-angiotensin system (RAS) inhibitors, β-blockers, mineralocorticoid receptor antagonists (MRAs), and sodium-glucose cotransporter-2 (SGLT2) inhibitors—have been shown to reduce mortality and morbidity. In contrast, HFpEF management focuses more on risk factor control and symptom-based therapy, with SGLT2 inhibitors being the only treatment that has shown significant clinical benefit. This literature review aims to evaluate the different roles of the four pillars of therapy in both phenotypes of heart failure and their implications for clinical practice. Although HFrEF treatment has made significant progress with strong clinical trial evidence, HFpEF management still requires further exploration to identify more effective strategies. Therefore, a deeper understanding of each phenotype's pathophysiology and therapeutic response is essential to improve patient outcomes and optimize heart failure management.
Antibacteria Susceptibility Test of Garlic (Allium sativum L.) Against Enterococcus faecalis As Root Canal Medicament Syaidah Ageng Kuswandi, Nabilla; Tarigan, Gita; Yuliadewi Rahmawati, Dicha
Al Makki Health Informatics Journal Vol. 3 No. 2 (2025): Al Makki Health Informatics Journal
Publisher : Al Makki Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57185/hij.v3i2.50

Abstract

This study aims to investigate the effect of garlic extract (GE) on the inhibition of Enterococcus faecalis (EF) bacterial growth. This study is a laboratory experimental research with a true experimental post-test only control group design, conducted in vitro using the well diffusion method. The experimental group consists of EF bacteria treated with different concentrations of GE, while the control group consists of EF bacteria treated with 0.2% chlorhexidine (CHX) as the positive control (PC) and 10% dimethyl sulfoxide (DMSO) as the negative control (NC). This study aims to observe the inhibition zone diameter (IZD) of bacterial growth after treatment with different concentrations of GE or control agents, measured in millimeters using a caliper. Phytochemical test revealed that the GE used in this study contains secondary metabolite compounds such as phenolics, flavonoids, saponins, and steroids, resulting in an IZD of 5.85 ± 0.26 at 100% GE and 3.25 ± 0.27 at 75% GE. The IZD formed on PC was 17.34 ± 0.33, and no IZD was formed on 50% GE or NC. The effect of GE in inhibiting the growth of EF was observed by the presence of inhibition zones at 100% and 75% concentrations, although it was not yet able to match the effectiveness of 0.2% CHX.
Literature Review: Analysis and Validation of the Effectiveness of Antidiabetic Drugs in the Biological Matrix Using the HPLC (High Performance Liquid Chromatography) Method Aulia Fernanda, Syahwa; Tirsta Az-zahra, Naila; Savitri Setyoasih, Teresa; Najwa Akmila, Ghefira; Bekti Pertiwi, Sekar; Maharani, Sabrina
Al Makki Health Informatics Journal Vol. 3 No. 2 (2025): Al Makki Health Informatics Journal
Publisher : Al Makki Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

High-Performance Liquid Chromatography (HPLC) is a widely used analytical method for the separation, identification, and quantification of compounds in complex biological matrices, such as plasma, serum, and urine. This article discusses the analysis and validation of the effectiveness of antidiabetic drugs using HPLC, focusing on sample preparation, column selection, mobile phase, and detectors used. Method validation is performed to ensure parameters such as specificity, linearity, precision, accuracy, limit of detection (LOD), and limit of quantification (LOQ) are met. Literature study from 18 journals showed that HPLC is a sensitive, specific, and efficient method for antidiabetic drug analysis. Preparation techniques such as protein precipitation and solid-phase extraction provide optimal results in minimizing biological matrix interferences. In addition, the Photodiode Array (PDA) detector proved superior in terms of sensitivity and analyzability at low concentrations compared to other detectors. By fulfilling all validation parameters, HPLC can be relied upon as a primary method for the analysis of antidiabetic drugs in biological matrices.
The Role Of Wearable Devices Technology In Monitoring Heart Health In The Elderly In Indonesia Sumiyati, Sumiyati
Al Makki Health Informatics Journal Vol. 3 No. 2 (2025): Al Makki Health Informatics Journal
Publisher : Al Makki Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57185/hij.v3i2.62

Abstract

Cardiovascular disease is still the leading cause of death in the world, including in Indonesia, with an increasing prevalence in the elderly. Limited access to health services, low digital literacy, and limited medical personnel in rural areas add to the complexity of heart health problems. This study aims to explore the role of wearable devices technology in monitoring heart health in the elderly in Indonesia. The research method uses a qualitative approach with a case study design. The research subjects consisted of 12 elderly people aged 60–75 years, 5 family members, and 3 health workers in the city of Bandung and Cirebon Regency. Data were collected through in-depth interviews, participatory observations, simple questionnaires, and documentation studies. The results of the study show that the majority of the elderly consider wearable devices useful in early detection of heart symptoms, increasing health awareness, and providing a sense of security for families. The main obstacles identified include low digital literacy (42%), device costs (33%), and inconvenience of use (25%). Seniors who live with their families are more compliant with devices than those who live alone. This study confirms that the effectiveness of wearable devices is influenced by social, economic, and cultural factors. With the support of families, health workers, and inclusive public policies, this technology has the potential to strengthen the digital transformation of elderly health services in Indonesia.
PFAS Exposure in Consumer Products and the Risk of Recurrent Miscarriage: A Clinical Study and Health Policy Implications Fauzia, Eva
Al Makki Health Informatics Journal Vol. 3 No. 2 (2025): Al Makki Health Informatics Journal
Publisher : Al Makki Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57185/hij.v3i2.63

Abstract

Exposure to Per- and Polyfluoroalkyl Substances (PFAS) from everyday consumer products has become a global issue of concern due to its persistent chemical properties and negative impact on reproductive health. This study aims to analyze the association between PFAS exposure and the risk of recurrent miscarriage in women of reproductive age in urban areas of Indonesia and examine the implications of public health policies. The research method uses a qualitative approach with a clinical case study design. Data were collected through in-depth interviews with hospital management, questionnaires to licensed medical personnel, field observations in respondents' households, and analysis of medical documents. The results showed that the majority of respondents were exposed to PFAS through various channels, such as the use of non-stick pans (73%), the consumption of fast food with plastic-coated packaging (67%), household cleaning products (80%), and drinking water in plastic packaging (100%). Interviews with hospital management indicate an increase in cases of recurrent miscarriages that cannot be medically explained, while medical personnel emphasize the need for PFAS regulation. These findings are in line with global research, but reveal gap research and gap policies in Indonesia. This study emphasizes the urgency of integrating environmental factors in clinical assessments and the preparation of national regulations to reduce PFAS exposure, as well as providing practical recommendations for the public in choosing safer products.
The Role of the Four Pillars in Heart Failure with Reduced Ejection Fraction (HFrEF) and Heart Failure with Preserved Ejection Fraction (HFpEF): How Different? Wili Mahendra, Dentino
Al Makki Health Informatics Journal Vol. 3 No. 2 (2025): Al Makki Health Informatics Journal
Publisher : Al Makki Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57185/hij.v3i2.49

Abstract

Heart failure (HF) remains a major clinical challenge, with two main phenotypes: heart failure with reduced ejection fraction (HFrEF) and heart failure with preserved ejection fraction (HFpEF). These conditions exhibit distinct pathophysiology, clinical manifestations, and therapeutic responses, requiring distinct management approaches. The four pillars of HFrEF therapy—renin-angiotensin system (RAS) inhibitors, β-blockers, mineralocorticoid receptor antagonists (MRAs), and sodium-glucose cotransporter-2 (SGLT2) inhibitors—have been shown to reduce mortality and morbidity. In contrast, HFpEF management focuses more on risk factor control and symptom-based therapy, with SGLT2 inhibitors being the only treatment that has shown significant clinical benefit. This literature review aims to evaluate the different roles of the four pillars of therapy in both phenotypes of heart failure and their implications for clinical practice. Although HFrEF treatment has made significant progress with strong clinical trial evidence, HFpEF management still requires further exploration to identify more effective strategies. Therefore, a deeper understanding of each phenotype's pathophysiology and therapeutic response is essential to improve patient outcomes and optimize heart failure management.
Antibacteria Susceptibility Test of Garlic (Allium sativum L.) Against Enterococcus faecalis As Root Canal Medicament Syaidah Ageng Kuswandi, Nabilla; Tarigan, Gita; Yuliadewi Rahmawati, Dicha
Al Makki Health Informatics Journal Vol. 3 No. 2 (2025): Al Makki Health Informatics Journal
Publisher : Al Makki Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57185/hij.v3i2.50

Abstract

This study aims to investigate the effect of garlic extract (GE) on the inhibition of Enterococcus faecalis (EF) bacterial growth. This study is a laboratory experimental research with a true experimental post-test only control group design, conducted in vitro using the well diffusion method. The experimental group consists of EF bacteria treated with different concentrations of GE, while the control group consists of EF bacteria treated with 0.2% chlorhexidine (CHX) as the positive control (PC) and 10% dimethyl sulfoxide (DMSO) as the negative control (NC). This study aims to observe the inhibition zone diameter (IZD) of bacterial growth after treatment with different concentrations of GE or control agents, measured in millimeters using a caliper. Phytochemical test revealed that the GE used in this study contains secondary metabolite compounds such as phenolics, flavonoids, saponins, and steroids, resulting in an IZD of 5.85 ± 0.26 at 100% GE and 3.25 ± 0.27 at 75% GE. The IZD formed on PC was 17.34 ± 0.33, and no IZD was formed on 50% GE or NC. The effect of GE in inhibiting the growth of EF was observed by the presence of inhibition zones at 100% and 75% concentrations, although it was not yet able to match the effectiveness of 0.2% CHX.
Literature Review: Analysis and Validation of the Effectiveness of Antidiabetic Drugs in the Biological Matrix Using the HPLC (High Performance Liquid Chromatography) Method Aulia Fernanda, Syahwa; Tirsta Az-zahra, Naila; Savitri Setyoasih, Teresa; Najwa Akmila, Ghefira; Bekti Pertiwi, Sekar; Maharani, Sabrina
Al Makki Health Informatics Journal Vol. 3 No. 2 (2025): Al Makki Health Informatics Journal
Publisher : Al Makki Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

High-Performance Liquid Chromatography (HPLC) is a widely used analytical method for the separation, identification, and quantification of compounds in complex biological matrices, such as plasma, serum, and urine. This article discusses the analysis and validation of the effectiveness of antidiabetic drugs using HPLC, focusing on sample preparation, column selection, mobile phase, and detectors used. Method validation is performed to ensure parameters such as specificity, linearity, precision, accuracy, limit of detection (LOD), and limit of quantification (LOQ) are met. Literature study from 18 journals showed that HPLC is a sensitive, specific, and efficient method for antidiabetic drug analysis. Preparation techniques such as protein precipitation and solid-phase extraction provide optimal results in minimizing biological matrix interferences. In addition, the Photodiode Array (PDA) detector proved superior in terms of sensitivity and analyzability at low concentrations compared to other detectors. By fulfilling all validation parameters, HPLC can be relied upon as a primary method for the analysis of antidiabetic drugs in biological matrices.
The Role Of Wearable Devices Technology In Monitoring Heart Health In The Elderly In Indonesia Sumiyati, Sumiyati
Al Makki Health Informatics Journal Vol. 3 No. 2 (2025): Al Makki Health Informatics Journal
Publisher : Al Makki Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57185/hij.v3i2.62

Abstract

Cardiovascular disease is still the leading cause of death in the world, including in Indonesia, with an increasing prevalence in the elderly. Limited access to health services, low digital literacy, and limited medical personnel in rural areas add to the complexity of heart health problems. This study aims to explore the role of wearable devices technology in monitoring heart health in the elderly in Indonesia. The research method uses a qualitative approach with a case study design. The research subjects consisted of 12 elderly people aged 60–75 years, 5 family members, and 3 health workers in the city of Bandung and Cirebon Regency. Data were collected through in-depth interviews, participatory observations, simple questionnaires, and documentation studies. The results of the study show that the majority of the elderly consider wearable devices useful in early detection of heart symptoms, increasing health awareness, and providing a sense of security for families. The main obstacles identified include low digital literacy (42%), device costs (33%), and inconvenience of use (25%). Seniors who live with their families are more compliant with devices than those who live alone. This study confirms that the effectiveness of wearable devices is influenced by social, economic, and cultural factors. With the support of families, health workers, and inclusive public policies, this technology has the potential to strengthen the digital transformation of elderly health services in Indonesia.
PFAS Exposure in Consumer Products and the Risk of Recurrent Miscarriage: A Clinical Study and Health Policy Implications Fauzia, Eva
Al Makki Health Informatics Journal Vol. 3 No. 2 (2025): Al Makki Health Informatics Journal
Publisher : Al Makki Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57185/hij.v3i2.63

Abstract

Exposure to Per- and Polyfluoroalkyl Substances (PFAS) from everyday consumer products has become a global issue of concern due to its persistent chemical properties and negative impact on reproductive health. This study aims to analyze the association between PFAS exposure and the risk of recurrent miscarriage in women of reproductive age in urban areas of Indonesia and examine the implications of public health policies. The research method uses a qualitative approach with a clinical case study design. Data were collected through in-depth interviews with hospital management, questionnaires to licensed medical personnel, field observations in respondents' households, and analysis of medical documents. The results showed that the majority of respondents were exposed to PFAS through various channels, such as the use of non-stick pans (73%), the consumption of fast food with plastic-coated packaging (67%), household cleaning products (80%), and drinking water in plastic packaging (100%). Interviews with hospital management indicate an increase in cases of recurrent miscarriages that cannot be medically explained, while medical personnel emphasize the need for PFAS regulation. These findings are in line with global research, but reveal gap research and gap policies in Indonesia. This study emphasizes the urgency of integrating environmental factors in clinical assessments and the preparation of national regulations to reduce PFAS exposure, as well as providing practical recommendations for the public in choosing safer products.

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