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Bayu Hari Mukti
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Health Sciences International Journal
Published by Ananda Health and Education
ISSN : -     EISSN : 30265037     DOI : -
Core Subject : Health, Science,
Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health
Health Sciences International Journal, HSIJ, launched in 2023, is an open-access journal that publishes articles in health and related sciences twice a year. Other analytical areas that HSIJ is interested in are biology and health. HSIJ has an editorial board that ensures that every issue of the journal contains cutting-edge articles on developments in the field of health.
Arjuna Subject : Profesi Kesehatan - Profesi Kesehatan (Lain-Lain)
Articles 2 Documents
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Search results for , issue "Vol. 2 No. 1 (2024): (In Progress)" : 2 Documents clear
Assessment of nitric oxide and peroxiredoxin along with frap in newly diagnosed patients of type 2 diabetes mellitus Mohd Zaid Kidwai; Maninder Bindra
HEALTH SCIENCES International Journal Vol. 2 No. 1 (2024): (In Progress)
Publisher : Ananda - Health & Education Foundation

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Abstract

Introduction: The pathophysiological mechanisms underlying Type 2 Diabetes Mellitus (T2DM) involve oxidative stress and impaired antioxidant defence systems. Hence, we aimed to assess Nitric Oxide (NO), Peroxiredoxin, and Ferric Reducing Ability of Plasma (FRAP) levels in newly diagnosed patients with T2DM. Methodology: In this case-control study, we included 63 patients as cases (newly diagnosed T2DM patients) and 63 as controls (healthy individuals). Detailed clinic-demographic data were recorded for all participants. Furthermore, fasting and post-prandial plasma glucose, HbA1c, NO, FRAP and peroxiredoxin were calculated. Statistical analysis was conducted to compare the findings between the two groups. Results: The preponderance of cases and controls were aged between 61 and 65. Male patients were the majority in both groups. The majority of reported cases involved alcohol consumption (p=0.0314*). The study revealed significant differences in kidney function, lipid profile, fasting and postprandial plasma glucose, and Hba1c levels between cases and controls (p<0.05). NO and FRAP levels in the case group were significantly lower (p<0.0001*), while peroxiredoxin levels were significantly higher (p<0.0001*). Conclusion: T2DM is associated with increased oxidative stress, indicated by elevated levels of Peroxiredoxin and decreased levels of FRAP and NO. These alterations in antioxidant defence mechanisms may serve as early indicators for the development of T2DM complications.
The Correlations between the determinants of women's health during pregnancy to the incidence of stunting Fathonatun Jannah
HEALTH SCIENCES International Journal Vol. 2 No. 1 (2024): (In Progress)
Publisher : Ananda - Health & Education Foundation

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Abstract

Abstract Background: WHO's target of reducing stunting below 20% has not been achieved in Indonesia, especially in Banjar Regency, with a prevalence of 33.45%. Lok Buntar village became the locus of stunting, where 38.7% of the 116 children under five were stunted, with several determining factors including age at pregnancy, a woman's height, birth spacing, nutritional status, and anemia. Objective: This study aims to determine the relation between determinants of maternal health during pregnancy and the incidence of stunting in Lok Buntar Village, Banjar Regency. Method: This type of observational analytic research with a retrospective design case-control approach. The total sample of 90 pregnant women, consisting of 45 cases and 45 controls, was taken by random sampling technique. Secondary data collection instruments used were checklists, cohorts of mothers and toddlers, and MCH books. Results: Findings show that the age of women during pregnancy is 84.0% at risk between 20 to 35 years, p-value 0.000. The spacing of births within two years was 70.4%, while the spacing of more than two years was 41.3%, with a p-value of 0.021. Respondents who have a height below 150 cm are 68.6%, with a p-value of 0.009. The nutritional status of pregnant women experiencing caloric energy deficiency is 84.2%, with a p-value of 0.002. Meanwhile, anemia and the risk of stunting were 89.7%, with a p-value of 0.000. Conclusion: The determinants of women's health during pregnancy have significant correlations with the incidence of stunting.

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