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Vania Snatika Putri
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Politeknik Indonusa Surakarta
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INDONESIA
Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat
Published by Politeknik Indonusa Surakarta
ISSN : 25486667     EISSN : 27759032     DOI : 10.46808
Core Subject : Health, Science,
Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Public Health
The journal includes various fields of pharmaceuticals sciences such as: Pharmacy, Pharmacokinetics, Community and Clinical Pharmacy, Medical, Alternative medicines, Synthetic Organic Chemistry, Organic Chemistry of Natural Material, Biochemistry, Chemical Analysis, Microbiology, Tissue Culture, Botany and Animals Related to Pharmaceutical Products, Midwifery, Health Analyst, Nutrition and Public Health, Pharmacology and Toxicology
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 10 Documents
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Search results for , issue "Vol 4 No 2 (2020): Desember" : 10 Documents clear
ANALISIS DETERMINAN KEJADIAN HIPERTENSI PADA PETANI KOPI DI WILAYAH KERJA PUSKESMAS SIMPANG TIGA KECAMATAN BUKIT KABUPATEN BENER MERIAH TAHUN 2017 Maulina Iriyanti; Fazidah Aguslina Siregar; Destanul Aulia
Jurnal Farmasindo Vol 4 No 2 (2020): Desember
Publisher : Program Studi D3 Farmasi Politeknik Indonusa Surakarta

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Abstract

Hypertension is a condition in which one 's blood pressure is above normal rate. Among 972 million people suffering from hypertension, 333 million of them are distributed in developed countries and the other 639 million people are in developing countries, including in Indonesia. The prevalence of hypertension in 2016 reached up to 30%. The objective of the research was to analyze the determinants of hypertension prevalence in coffee growers in the area of Sp. 3 Bukit Sub-district, Bener Meriah District. It is an observational research using case control design. The case group consisted of 55 coffee growers suffering from hypertension and the control group consisted of 55 coffee growers who did not suffer from hypertension, or they were in ratio 1:1. The data were analyzed by multiple logistic regression testing. The variable with the most dominant influence on the prevalence of hypertension in the working are of Puskesmas (Public Health Center) at Sp.3 Bukit Sub-district, Bener Meriah District in 2017 was the habit of drinking coffee with (B) 8.174, 95% CI=3.253 ­20, 539, p=(0.000) which indicates that patients with hypertension had 8.065 times higher risks to get hypertension attack with frequent coffee drinking habit compared to those who did not suffer from hypertension. It is suggested that medical workers improve health promotion to the society concerning hypertension and provide counseling about the hazard of smoking and drinking coffee resulting in hypertension.
POTENSI PENGGUNAAN TANAMAN ANTING-ANTING (Acalypha indica L) SEBAGAI ZAT AKTIF PADA PEMBUATAN LIP BALM DAN SEDIAAN KOSMETIK LAINNYA Iin Suhesti; Anisa Hariyani; Aisyah Nur Hidayah; Arofah Frisca Sahara
Jurnal Farmasindo Vol 4 No 2 (2020): Desember
Publisher : Program Studi D3 Farmasi Politeknik Indonusa Surakarta

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Abstract

Lip balm merupakan salah satu produk kosmetik yang paling sering digunakan saat ini, terutama oleh kaum wanita. Tujuan penggunaan lip balm yaitu untuk melembabkan bibir dan mengurangi bibir pecah-pecah. Tetapi banyak sediaan lip balm yang menggunakan bahan kimia berbahaya sehingga dapat mengakibatkan bibir menjadi hitam, iritasi sampai ke kanker kulit, sehingga diperlukan lip balm yang menggunakan zat aktif dari bahan alam salah satunya adalah tanaman Anting-anting (Acalypha indica L). Penelitian ini dilakukan dengan metode narative review yang bertujuan untuk mengetahui potensi penggunaan tanaman anting-anting (Acalypha indica L) sebagai zat aktif pada pembuatan lip balm dan sediaan kosmetik lainnya. Hasil dari beberapa literatur diperoleh golongam flavonoid yang berhasil diidentifikasi dari tanaman anting-anting (Acalypha indica L) adalah isoflavon, flavon, flanolol, flavanon, dihidroksiflavonol, khalkon dan antosianidin. Ditemukan juga kandungan antioksidan dengan persen inhibisi (IC50) menggunakan pelarut etanol fraksi TH, HB, HA secara berturut-turut adalah 127,87 ppm; 132,97 ppm; dan 133,68 ppm dengan kategori sedang. Sedangkan dengan pelarut heksana, kloroform dan methanol diperoleh aktivitas antioksidan yang signifikan dengan nilai IC50 yaitu 6,19 ± 0,010 mg/ml; 5,70 ± 0,050 mg/ml; dan 7,79 ± 0,020 mg/ml. Kadar antioksidan pada daun dengan konsentrasi 200, 400, dan 600 μg yaitu 17,12%; 26,87%; dan 31,14%. Sedangkan pada akar dengan konsentrasi 200, 400, dan 600 μg yaitu 26,16%; 41,84%; dan 53,27%. Berdasarkan kandungan flavonoid dan antioksidan, tanaman anting-anting (Acalypha indica L) berpotensi sebagai zat aktif pada pembuatan lip balm dan sediaan kosmetik lainnya.
ANALISIS DETERMINAN PERILAKU SEKSUAL BERESIKO PADA REMAJA DI SMA LAMPUNG SELATAN TAHUN 2020 Dewi Rahayu; Novita Lestari; Abikusno Djamaluddin
Jurnal Farmasindo Vol 4 No 2 (2020): Desember
Publisher : Program Studi D3 Farmasi Politeknik Indonusa Surakarta

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Abstract

Sexual behavior is said to be risky if the behavior brings unwanted consequences such as abortion, pregnancy outside marriage and Sexually Transmitted Diseases (STDs). In 2019 there were 78 cases of pregnancy and childbirth among adolescents in the working area of ​​Candipuro Health Center. This type of research is quantitative. Analytical research design with cross-sectional approach. The population is all high school students grade X, XI, XII in South Lampung Regency as many as 15,259 students. with a sample of 429 respondents. Data analysis used univariate analysis with percentages, bivariate analysis with Chi Square and multivariate analysis with multiple logistic regression. The results showed that there was a relationship between knowledge with at risk sexual behaviorwith p value 0,001,there was a relationship between attitudes with at risk sexual behaviorwith p value 0,000, there was a relationship betweenimformation sources with at risk sexual behavior with p value 0,002, there was a relationship between friends of the same age with at risk sexual behavior with p value 0,000, there was a relationship the role of parents with at risk sexual behavior with p value 0,017. The dominant factor influencing risky sexual behavior in teens in South Lampung High School in 2020 is attitude with OR 12,064. Efforts that can be made to reduce risky sexual behavior in adolescents by increasing knowledge about reproductive health that can be done through adolescent health care service programs (PKPR) in collaboration with puskesmas.
PENETAPAN KADAR FLAVONOID PADA PELEPAH PISANG RAJA (Musa acuminata Colla. forma cerifera Back.) DENGAN VARIASI LAMA WAKTU EKSTRAKSI Praptanti Sinung Adi Nugroho; Danang Muhammad Sholihin; Aptika Oktaviana Trisna Dewi
Jurnal Farmasindo Vol 4 No 2 (2020): Desember
Publisher : Program Studi D3 Farmasi Politeknik Indonusa Surakarta

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Abstract

Indonesia is one of the banana exporting countries. There are so many kinds of bananas, one of which is plantain. Plantain contains several ingredients such as flavonoids which have several properties including antioxidants and antimicrobial activity. This study aims to determine the levels of flavonoids in the ethanol extract of plantain stalks with variations in extraction time. The method used was experimental research with three groups of plant extraction treatments, namely extraction time of 2, 3, and 5 days. The extraction method uses maceration with 70% ethanol solvent. Flavonoid levels were obtained using the UV-Vis spectrophotometric method. The yield of extracted results obtained for the duration of 2, 3, and 5 days was 9.97% respectively; 12.62% and 14.14% with average levels of flavonoids obtained respectively 2.69 mg / gram; 5.10 mg / gram and 8.82 mg / gram
EFEKTIVITAS PENYULUHAN KESEHATAN RAMUAN JAMU SAINTIFIK UNTUK PENURUN KADAR ASAM URAT PADA IBU-IBU PKK DI DUKUH BASIN KEBONARUM KLATEN Annisa Swaraswati; Indri Kusuma Dewi; Agus Kirwanto
Jurnal Farmasindo Vol 4 No 2 (2020): Desember
Publisher : Program Studi D3 Farmasi Politeknik Indonusa Surakarta

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Abstract

Berdasarkan hasil Riskesdas tahun 2013, prevalensi penyakit sendi berdasarkan gejala yaitu NTT (33,1%), Jawa Barat (32,1%) dan Bali (30%). Penggunaan tumbuhan yang ada di Indonesia sangat minim karena kurangnya dukungan terhadap program saintifikasi jamu. Masyarakat belum mengetahui ramuan jamu saintifik sebagai penurun kadar asam urat. Berdasarkan hasil studi pendahuluan, mayoritas warga Dukuh Basin belum mengetahui ramuan jamu saintifik (daun kepel, herba tempuyung, kayu secang, herba meniran, kunyit dan temulawak) sebagai penurun kadar asam urat. Penelitian ini bertujuan untuk mengetahui efektivitas penyuluhan kesehatan ramuan jamu saintifik untuk penurun kadar asam urat pada Ibu-ibu PKK di Dukuh Basin. Penelitian ini menggunakan quasi eksperiment design dengan rancangan one grup pretest posttest. Populasi dalam penelitian ini adalah Ibu-ibu PKK di Dukuh Basin dengan teknik purposive sampling. Instrumen yang digunakan berupa angket. Hasil penelitian didapatkan nilai mean pretest 69,51 dan posttest 97,44 dengan selisih nilai mean 27,92. Hasil analisis bivariat menggunakan t-test P=0,000 (P<0,05) yang menunjukan bahwa ada pengaruh yang signifikan antara peningkatan pengetahuan sebelum penyuluhan dan sesudah penyuluhan. Kesimpulan dari penelitian ini adalah penyuluhan kesehatan tentang ramuan jamu saintifik untuk penurun kadar asam urat efektif terhadap peningkatkan pengetahuan Ibu-ibu PKK di Dukuh Basin.
FORMULASI DAN UJI FISIK SEDIAAN SALEP EKSTRAK DAUN JAMBU AIR (Syzygium aqueum (Burm F.) Alston) DENGAN VARIASI TIPE BASIS SALEP Yunita Dian Permatasari; Nava Kirani; Umi Nafisah; Aptika Oktaviana Trisna Dewi
Jurnal Farmasindo Vol 4 No 2 (2020): Desember
Publisher : Program Studi D3 Farmasi Politeknik Indonusa Surakarta

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Abstract

Water guava leaves contain chemical compounds such as flavonoids, tannins and saponins. As a medicinal preparation, water guava leaves can be made into an ointment. This study aims to determine the ointment formulation, conduct physical evaluation of the ointment and determine the effect of different types of ointment base extracts of water guava leaves on physical properties. Water guava leaves extract was made by maceration method of ethanol 70% solvent. Ointment are made with four types of bases which include hydrocarbon base, absorption, water washed and water soluble. Each formula was tested for physical properties including organoleptic, homogeneity, pH, dispersal, and adhesion. The data obtained were then analyzed using the One Way ANOVA test method. The results showed that the four ointment formulas had different shapes and colors, had the same odor and had good homogeneity. The pH test of the hydrocarbon bases ointment was 4.09, the absorption bases was 3.98, the water-washed bases was 4.33, and the water-soluble base was 3.87 did not meet the pH test parameters. The dispersibility test results for hydrocarbon bases 6.20 cm, absorption basis 6.19 cm met the test parameters, base ointment was washed with water 3.99 cm, water soluble base 3.49 cm did not meet the dispersibility test parameters. The results of the adhesion test for hydrocarbon bases 11.85, absorption bases 12.11, water washable bases 20.03, and water soluble bases 4.97, which means they meet the adhesion test parameters. The results of the One Way ANOVA test showed that the pH test, spreadability and adhesion had the same significant value, namely 0.000 <0.05. These results indicate that the different types of ointment bases used have a significant effect on pH, dispersion and adhesion.
FAKTOR YANG BERHUBUNGAN DENGAN KUNJUNGAN POS PEMBINAAN TERPADU (POSBINDU) PENYAKIT TIDAK MENULAR DI KABUPATEN TULANG BAWANG BARAT TAHUN 2020 Maryati Maryati; Endang Budiati; Noviansyah Noviansyah
Jurnal Farmasindo Vol 4 No 2 (2020): Desember
Publisher : Program Studi D3 Farmasi Politeknik Indonusa Surakarta

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Background: The low visit of Posbindu PTM shows the low awareness of community about the importance of Posbindu PTM. It means there is a gap of Posbindu PTM services with the response of the community. Purpose: to know the factors related to Posbindu PTM visit in Tulang Bawang Barat Regency in 2020. Methods: Type of research is quantitative with cross sectional approach. The population is the target of Posbindu (age>15 years) and adopted 439 samples. Data analysis using univariate analysis, bivariate (chi square) multivariate (multiple logistic regression). Results: there is a relationship between knowledge (p=0.000), attitude (p=0.000), education (p=0,000), income (p=0.004), accessibility (p=0.007) and support of health workers (p=0.000) with Posbindu PTM visit. Knowledge is the dominant factor related to Posbindu PTM visits (p = 0.000).Conclusion: Determinant of Posbindu PTM Visit are knowledge, attitude, education, income, accessibility and support of health workers with Posbindu PTM visit, that’s why this research perfecting Standard of operational procedure and disseminating information on hypertonic infusion fluid and monitoring it regularly and continuously.
FORMULASI DAN EVALUASI FISIK SEDIAAN LIP BALM EKSTRAK ETANOL UMBI BIT (Beta vulgaris var. rubra (L) Moq.) SEBAGAI PEWARNA ALAMI Erlin Devi Isnaini; Iin Suhesti; Aptika Oktaviana Trisna Dewi
Jurnal Farmasindo Vol 4 No 2 (2020): Desember
Publisher : Program Studi D3 Farmasi Politeknik Indonusa Surakarta

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Abstract

Beetroot (Beta vulgaris var. rubra (L) Moq.) has the pigment betasianin which produces a red color and is often used as a natural coloring agent in food so that it can be developed to be used as a dye in cosmetic products. The purpose of this study was to determine the lip balm preparation formulation of beetroot extract (Beta vulgaris var. rubra (L) Moq.) as a natural dye and physical evaluation. In this study using a descriptive experimental method using variations in the concentration of beetroot extract. The variations in the concetration of beetroot extract were F1 0%, F2 1%, F3 5% and F4 10%. From each formula, a physical lip balm test was carried out including the organoleptic test, homogeneity test, pH test, melting point test, and preference test. The result showed that the lip balm preparation on F1 was yellow, F2 was peach, F3 was pink and F4 was maroon. F1, F2, F3 have the distinctive smell of oleum cacao, while F4 has the distinctive smell of lanolin. And semi solid preparation. Homogeneity test F1, F2, F3 and F4 have homogeneous preparations. pH test at F1 5.26; F2 5.03; F3 4.87 and F4 4.76. melting point test of all formulas melting at 50°C for F1 and F2 for 12 minutes, F3 10 minutes and F4 for 6 minutes. The preference test concluded that the panelists preferred F4.
STUDI KOMPUTASI REAKSI SUBTITUSI DARI 1-BROMOHEPTANA DENGAN ION HIDROKSI MENGGUNAKAN PENDEKATAN AB-INITIO Mirella Fonda Maahury
Jurnal Farmasindo Vol 4 No 2 (2020): Desember
Publisher : Program Studi D3 Farmasi Politeknik Indonusa Surakarta

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Substitution reaction is a simple reaction that can occur through the SN1 pathway. One of the reactions included in the substitution reaction is the reaction between alkane halides and hydroxy ions. The computational calculation has done for substitution reaction between 1-bromoheptane and hydroxy ion. The purpose of computational calculations is to obtain a stable structure, and thermodynamic aspect of the reaction. The calculation was using the ab-initio approach HF-SCF (Hatree Fock-Self Consistent Field) with 6-31G(d) as a basis set. The calculation is done in gas phase. The optimized structure of reactant is being in complex reactant. Gibbs Free energy from the calculation is about - 255.53 kJ/mol. It is mean that the reaction is happen spontaneously.
PROFIL SWAMEDIKASI ANALGETIK PADA MAHASISWA POLITEKNIK INDONUSA SURAKARTA Siti Ma'rufah; Khusnul khotimah; Aptika Oktaviana Trisna Dewi; Riyan Setiyanto
Jurnal Farmasindo Vol 4 No 2 (2020): Desember
Publisher : Program Studi D3 Farmasi Politeknik Indonusa Surakarta

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Self-medication is a community effort to treat symptoms without a doctor's prescription. With self-medication, complaints can be resolved and resolved quickly and effectively. Medicines that are sold freely in kiosks make it easier for people to get drugs to carry out self-medicated actions. The purpose of this study was to determine the profile of using analgesic drugs by self-medication in students of Polytechnic Indonusa Surakarta. This research is a cross sectional approach. Data collection using a questionnaire via google form to 88 respondents. The sampling technique used is random sampling by taking sample members randomly. Quantitative data processing uses Microsoft Office Excel.The results showed that the characteristics of the respondents who participated in this study were mostly women aged 17-25 years from 5 study programs, namely D3 Pharmacy, D3 Mass Communication, D3 Hospitality, D3 Information Management and D3 Automotive Machinery. The most pain complaints experienced by respondents were headache, toothache and menstrual pain. Respondents tended to use 1 type of synthetic drug or traditional / herbal medicine with only 1 type of active ingredient composition and more often mentioned the generic name of the drug when buying the drug. Respondents preferred paracetamol to deal with pain complaints. The place of purchase of self-medicated drugs is more dominant in pharmacies. Most of the reasons for doing self-medication were because of the experience of recovering with the same medicine and the perception that the disease was mild.

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