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International Journal of Applied and Scientific Research (IJASR)
Published by MULTITECH PUBLISHER
ISSN : -     EISSN : 30257670     DOI : https://doi.org/10.59890/ijasr.v2i2
International Journal of Applied and Scientific Research (IJASR) is a multidisciplinary peer reviewed Journal aimed to publish original research papers in all main branches of science (All scientific disciplines) with a double-blind peer reviewed refereed journal that publishes empirical, conceptual, and review papers of exceptional quality that contribute to enrich the humans life.
Arjuna Subject : Umum - Umum
Articles 5 Documents
Search results for , issue "Vol. 2 No. 11 (2024): November 2024" : 5 Documents clear
Impact of Tigernuts on Blood Glucose and Insulin Levels in Normal Weight Male Humans Edokpolor N, Igbinovia; Ohiwerei Wisdom O; Blackie Okosun H; Edebiri Ogbemudia E; Otaye Micheal O; Ohiwerei Faith O
International Journal of Applied and Scientific Research Vol. 2 No. 11 (2024): November 2024
Publisher : MultiTech Publisher

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Abstract

Tigernuts contain bioactive compounds such as sterols, alkaloids, tannins, saponins, resins, and vitamins E and C. This study examined their effects on blood glucose and insulin levels in normal-weight male subjects under resting conditions. Methods: Forty non-habitual tigernut chewers, aged 18–28 years, participated. After recording anthropometric data, subjects rested for 90 minutes. Blood glucose levels were measured using the enzymatic method of Barham and Trinder with a glucometer. Insulin levels were assessed using the ELISA Teco kit following Tiez and Andresen's method. On a separate day, the same subjects consumed 5g of tigernuts as a bolus, followed by 50ml of water. After another 90-minute rest, blood glucose and insulin levels were reassessed. Statistical analysis was conducted using GraphPad Prism Version 8.1. Results: Tigernut consumption led to a slight reduction in blood glucose levels (92.66 ± 2.156 to 89.61 ± 1.907 mg/dl), though not statistically significant. However, insulin levels showed a significant decrease (P<0.05, 4.220 ± 0.297 to 1.705 ± 0.061 µg/ml). Conclusion: Tigernuts demonstrated both blood glucose and insulin-lowering effects in normal-weight male subjects
Effects of Tigernuts on Blood Urea, Uric Acid and Creatinine Levels in the Normal Weight Male Humans Igbinovia Edokpolor N; Ohiwerei Wisdom O; Festus Oloruntoba O; Ohiwerei Faith O; Onokevbagbe Elisha O
International Journal of Applied and Scientific Research Vol. 2 No. 11 (2024): November 2024
Publisher : MultiTech Publisher

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Abstract

Natural antioxidants are gaining significant attention from nutritionists, food manufacturers, medical professionals, and consumers due to their numerous health benefits. This study explored the potential effects of tigernuts on blood urea, uric acid, and creatinine levels in normal-weight male subjects under resting conditions, as well as the possible mechanisms involved. Methods: A total of forty (40) non-habitual tigernut chewers, aged 18–28 years, participated in the study. After recording the anthropometric data of the control group, the subjects rested for 1 hour and 30 minutes. Urea levels were measured colorimetrically using the Urease-Berthelot’s Method, where urea in plasma was hydrolyzed to ammonia in the presence of urease, and the resulting ammonia was detected photometrically through Berthelot’s reaction. Uric acid was determined using an enzymatic colorimetric method, while creatinine was assessed using the Modified Jaffe’s Method, in which creatinine in the sample reacted with picrate in an alkaline medium to form a colored complex, measured within a short period to minimize interference.On a separate day, 5g of tigernuts were given to the same subjects—who had previously served as controls—to be chewed as a bolus. Findings indicated that tigernuts significantly reduced (P < 0.05) blood urea levels post-consumption (from 16.32 ± 0.759 to 11.76 ± 1.325 mg/dl). However, uric acid levels significantly increased (P < 0.05) following ingestion (from 2.438 ± 0.439 to 4.851 ± 0.393 mg/dl). Blood creatinine levels decreased from 1.778 ± 0.093 to 1.617 ± 0.089 g/dl, though this reduction was not statistically significant. This study suggests that tigernuts have beneficial effects on renal urea and creatinine levels, supporting their consumption for maintaining kidney health
Influence of Tigernuts on the Antioxidant Vitamins Levels in Normal Weight Male Human Subjects Edokpolor N, Igbinovia; Wisdom O, Ohiwerei; Festus Oloruntoba O; Onokevbagbe Elisha I; Adisa W A
International Journal of Applied and Scientific Research Vol. 2 No. 11 (2024): November 2024
Publisher : MultiTech Publisher

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Abstract

Tubers have been recognized as a valuable source of essential macro- and micronutrients vital for overall health. Among these, tigernut has been gaining popularity due to its rich composition. This tuber contains bioactive compounds such as sterols, alkaloids, tannins, saponins, resins, and vitamins E and C. Natural antioxidants have attracted significant attention from nutritionists, food manufacturers, medical professionals, and consumers due to their numerous health benefits. This study aimed to examine the effect of tigernuts on human vitamin A, C, and E levels in normal-weight male subjects under resting conditions, as well as to explore potential mechanisms of action. Methods: The study involved forty (40) male participants who were non-habitual tigernut consumers, aged 18–28 years. Anthropometric data were recorded for control subjects, who then rested for 1 hour and 30 minutes. Serum vitamin C levels were analyzed using a spectrophotometric method, with ascorbic acid showing maximum absorption at 478.5 nm in methanolOn a separate day, each participant was given 5g of tigernut to chew as a bolus, with the same subjects serving as both control and test participants.The findings revealed that tigernut consumption significantly increased (P < 0.05) vitamin E levels from 0.09573 ± 0.021 to 0.8430 ± 0.057 mg/%. In contrast, vitamin A levels significantly decreased (P < 0.05) from 291.8 ± 29.50 to 97.89 ± 32.36 mg/%. Vitamin C levels also declined post-consumption, from 1.586 ± 0.201 to 1.188 ± 0.080 mg/%, though this decrease was not statistically significant.The results suggest that tigernut consumption enhances vitamin E levels while reducing both vitamin A and C levels in normal-weight male subjects
The Role of Green Infrastructure in Mitigating Urban Flooding Jinto P J
International Journal of Applied and Scientific Research Vol. 2 No. 11 (2024): November 2024
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Abstract

Urban flooding has emerged as a critical challenge due to rapid urbanization, climate change, and the loss of natural drainage systems. Traditional grey infrastructure, such as stormwater drains and concrete embankments, often fails to handle increasing rainfall intensity, leading to waterlogging and economic losses. Green infrastructure (GI) offers a sustainable approach by integrating natural and semi-natural systems to manage stormwater effectively. This paper examines the role of green infrastructure in mitigating urban flooding through mechanisms such as permeable surfaces, green roofs, wetlands, urban forests, and rain gardens. By enhancing water absorption, reducing runoff, and improving resilience to extreme weather events, GI provides a cost-effective and ecologically beneficial alternative to conventional flood control methods. The paper also explores global case studies of successful GI implementation and presents policy recommendations for cities aiming to integrate green infrastructure into urban planning
Evaluation of the Histological Effects of Allium Cepa Administration on the Prostate Histology and Prostate Specific Antigen of Male Albino Rats Induced with Ciprofloxacin Mathew, Uwuigbe; Ohiwerei Wisdom Omogbai; Edebiri Ogbemudia E; Ajanwachukwu Ogbonna Wilson; Oriahoghen E E
International Journal of Applied and Scientific Research Vol. 2 No. 11 (2024): November 2024
Publisher : MultiTech Publisher

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Abstract

The primary objective of this study is to assess the histological impact of Allium cepa administration on prostate histology and prostate-specific antigen (PSA) levels in male albino rats that were induced with ciprofloxacin. A total of 100 albino rats, each weighing between 150–250g, were used in the experiment. The experimental group was further divided into four subgroups, each containing 10 rats, labeled as Groups A, B, C, D, and E. Group A served as the control, while Group B received only ciprofloxacin. Group C was administered ciprofloxacin along with 100mg of Allium cepa extract, whereas Group D received ciprofloxacin and 200mg of Allium cepa extract. Group E was treated solely with Allium cepa extract. Groups B, C, and D were given 22.86 mg/kg of oral ciprofloxacin (500 mg/tablet), manufactured by Fidson Health Care Ltd. The ciprofloxacin was obtained from a reputable pharmaceutical store in Ekpoma, Edo State, and administered via gavage. The control group was provided with only water and food. The PSA levels in control and test subjects were recorded as Mean ± SEM. For the control group, the PSA level was 0.6250 ± 0.085 ng/ml. The PSA levels for test groups B, C, D, and E were 1.575 ± 0.417 ng/ml, 1.200 ± 0.123 ng/ml, 1.125 ± 0.048 ng/ml, and 3.300 ± 0.835 ng/ml, respectively. Notably, only Group E exhibited a significant increase (P<0.05) in PSA levels when compared to the control group.In conclusion, this study indicates that exposure to ciprofloxacin and Allium cepa at mild or moderate doses can lead to severe histopathological changes in the testis, prostate, and epididymis, with the exception of the brain

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