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Indra Hadi
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The Indonesian Journal of General Medicine
Published by International Medical Journal Corp. Ltd.
ISSN : -     EISSN : 3048104X     DOI : -
Core Subject : Health,
Dentistry Health Professions Medicine & Pharmacology Public Health Veterinary
ims: The Indonesian Journal of General Medicine aims to advance the field of medicine by disseminating high-quality research findings that are accessible to a broad audience of healthcare professionals, researchers, and policymakers. The journal is committed to supporting the development of medical knowledge and practice in Indonesia and globally, fostering innovative research and evidence-based clinical practices. Scope: The journal covers a wide range of topics within the general medical field, including but not limited to: Clinical studies in various medical disciplines Epidemiological research and public health issues Innovations in diagnostic techniques and treatments Reviews on current practices and emerging trends in medicine Case studies and clinical trials Health policy and medical education The Indonesian Journal of General Medicine welcomes submissions from all areas of medicine, particularly those that have significant implications for patient care, public health, and policy-making. The journal encourages submissions that offer new insights, propose novel approaches, or address challenges pertinent to the Indonesian and international medical communities.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 4 Documents
 1 
Search results for , issue "Vol. 4 No. 1 (2024): The Indonesian Journal of General Medicine" : 4 Documents clear
The Analysis Study of Comparison of Effectiveness and Safety of Inhalers in Mild-to Moderate Asthma in Adults: A Comprehensive Systematic Review Harve, Akbar Fathoni
The Indonesian Journal of General Medicine Vol. 4 No. 1 (2024): The Indonesian Journal of General Medicine
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/d1wkvf29

Abstract

Background: Asthma, a prevalent and potentially debilitating chronic disease, is traditionally managed using reliever medications such as short-acting β2-agonists (SABA) or low-dose inhaled corticosteroids (ICS). Recent evidence, however, indicates that a combination of as-needed ICS and a rapid-acting long-acting β2-agonist (LABA) provides superior outcomes compared to SABA alone. Furthermore, this combination therapy is at least as effective as regular ICS in mitigating the risk of exacerbations. This emerging evidence highlights a significant shift in treatment strategies for mild asthma, underscoring the potential for enhanced management and improved patient outcomes with the new therapeutic approach. Methods: Following PRISMA 2020 guidelines, this systematic review focused exclusively on full-text articles published in English between 2014 and 2024. Result: The study conducted a comprehensive review of over 400 publications sourced from reputable databases, including ScienceDirect, SagePub, and PubMed. Folowing an initial screening, eight publications were identified as warranting more in-depth analysis. Conclusion: The study found that as-needed ICS/LABA is effective in preventing exacerbations in mild-to-moderate asthma patients, but less effective than regular ICS in improving FEV1 and ACQ scores. Combining ICS/LABA with SMART regimen was highest for severe exacerbations prevention.
The Analysis Study of Prevalence, Diagnosis, and Management of Cataract in Adult Eye: A Comprehensive Systematic Review Dunand, Muhammad Luthfi; Dunand, Indira Ulfa; Hadi, Indra
The Indonesian Journal of General Medicine Vol. 4 No. 1 (2024): The Indonesian Journal of General Medicine
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/zebys738

Abstract

Background: Cataract remains a major cause of visual impairment worldwide. However, in many countries cataract surgery is easily available. Cataract surgery is a kind of effective way to deal with cataract, but it is acompanied with many surgical complications and expensive costs that present enormous social and economic problems to a society, especially in the remote and poor areas of developing countries. The aim: The aim of this study to show about prevalence, diagnosis, and management of cataract in adult eye. Methods: By the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020, this study was able to show that it met all of the requirements. Result: Eight publications were found to be directly related to our ongoing systematic examination after a rigorous three-level screening approach. Subsequently, a comprehensive analysis of the complete text was conducted, and additional scrutiny was given to these articles. Conclusion: Cataracts to increase in the near future due to an increase in the aging population and pre-senile cataracts. The current study also provides clinical determinants for cataract and cataract surgery. Since cataract has emerged as a public concern and the cost burden for cataract surgery has increased with an aging population, it is expected that the present study will form a cornerstone for further investigations and the establishment of a public health plan.
The Analysis Study of Effects of Probiotics, Prebiotics, Lactoferrin and Combination Products for Prevention of Mortality and Morbidity in Preterm Infants: A Comprehensive Systematic Review Aldila, Raden Rara Farah; Erlich, Willyam Arnando Deggas
The Indonesian Journal of General Medicine Vol. 4 No. 1 (2024): The Indonesian Journal of General Medicine
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/xt75hd29

Abstract

Introduction: Preterm infants, particularly those with very low birth weight (VLBW), are at heightened risk for life-threatening complications such as necrotizing enterocolitis (NEC), late-onset sepsis, feeding intolerance, and other gastrointestinal and infectious conditions. In recent years, there has been growing interest in exploring non-pharmacological interventions, such as probiotics, prebiotics, and lactoferrin, to mitigate these risks and improve outcomes in preterm infants. Methods: This systematic review adhered to the PRISMA 2020 guidelines to ensure transparency and consistency. Results: Eight relevant studies were identified and assessed in detail. Findings indicate that probiotic, prebiotic, and lactoferrin interventions have potential benefits in reducing NEC incidence and improving clinical outcomes in VLBW infants. For instance, a study by Chowdhury et al. (2016) found a significantly lower incidence of NEC in the probiotic group (1.9%) compared to the control group (11.5%) with a p-value of 0.044. Additionally, the duration of hospital stay was shorter for the probiotic group, averaging 15.82 days versus 19.57 days for controls (p < 0.001). These results support the use of probiotics in enhancing recovery in VLBW infants. This review highlights the potential of probiotics, prebiotics, and lactoferrin in reducing the incidence of NEC and sepsis, as well as promoting faster achievement of full enteral feeding and shorter hospital stays in VLBW infants. However, the heterogeneity among studies regarding probiotic strains, dosages, and study designs complicates definitive conclusions. Further research is needed to establish standardized treatment protocols and ensure the long-term safety of these interventions in clinical practice.
Association Between Recurrence Rates of Colorectal Cancer and Carcinoembryonic Antigen Levels, Histopathological Features, Tumor-Infiltrating Lymphocytes, and Lymphatic Invasion at H. Adam Malik Central General Hospital, Medan Mohammad, Fawzan; Muhar, Adi Muradi; Siregar, Edwin Saleh
The Indonesian Journal of General Medicine Vol. 4 No. 1 (2024): The Indonesian Journal of General Medicine
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/eqs5ry48

Abstract

Introduction: In Indonesia, colorectal cancer ranks fourth in cancer incidence, with an estimated over 30,000 new cases each year. This study aims to investigate the association between colorectal cancer recurrence rates and CEA levels, histopathology, tumor-infiltrating lymphocytes, and lymphatic invasion at H. Adam Malik Central General Hospital, Medan. Methods: This cross-sectional study investigates the correlation between colorectal cancer recurrence and clinical parameters such as CEA levels, histopathology, TIL, and lymphatic invasion using retrospective data from patients at H. Adam Malik Central General Hospital in North Sumatra. Results:  Out of 75 patients identified, 45 met the inclusion criteria. The study found significant relationships between recurrence and CEA levels (p=0.007), histopathological grade (p<0.001), and lymphovascular invasion (p=0.026), while tumor-infiltrating lymphocytes showed no significant correlation (p=0.358). Conclusion: Colorectal cancer recurrence are primarily shown in male patients with rectal and sigmoid tumors, predominantly adenocarcinoma at stage IIb. Significant CEA levels, moderate histological differentiation, tumor-infiltrating lymphocytes, and lymphovascular invasion were identified.

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