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Medical Sains : Jurnal Ilmiah Kefarmasian
Published by Universitas Muhammadiyah Ahmad Dahlan Cirebon
ISSN : 25482114     EISSN : 25412027     DOI : https://doi.org/10.37874/ms
Core Subject : Health,
Medicine & Pharmacology
The Medical Sains journal is a scientific publication media published by the Muhammadiyah Cirebon College of Pharmacy which is published 4 (four) times in 1 (one) year, namely January-March, April-June, July-September and October-December. The journal contains research in the field of pharmacy covering the fields of formulation, pharmacology, communication pharmacy, A natural chemical chemistry, pharmacognomy and other health sciences which is a means for lecturers and researchers in the health sector to share knowledge and establish cooperation in implementing the Tri Dharma of Higher Education. Purpose and Scope The objective of the publication of the Medical Science journal is to publish articles in the field of pharmacy and other health as well as application of pharmaceutical . Based on this, the editorial board of Medical Sains invites lecturers and researchers to contribute to submit research articles related to the following themes: 1. Pharmaceutical formulation technology 2. Pharmacology 3. Community pharmacy 4. Clinical Pharmacy 5. Natural material chemistry 6. Pharmacognosy 7. Pharmaceutical Analysis and Medicinal Chemistry . All papers submitted to medical science journals will be examined by peer review partners who are tailored to their respective fields.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 11 Documents
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Search results for , issue "Vol 5 No 2 (2021)" : 11 Documents clear
FORMULASI DAN UJI STABILITAS GEL HAND SANITIZER EKSTRAK ETANOL BUAH BELIMBING WULUH (Averrhoa bilimbi L.) KONSENTRASI 1% DAN 3%: FORMULATION AND STABILITY TEST OF HAND SANITIZER GEL CONTAIN 1% AND 3% ETHANOL EXTRACT OF BELIMBING WULUH (Averrhoa bilimbi L.) Yayan Rizikiyan; Ine Suharyani; Opi Nurholipah; Muhammad Yani Zamzam; Rima Yulia Senja
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 5 No 2 (2021)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v5i2.829

Abstract

Buah belimbing wuluh (Averrhoa bilimbi L.) mengandung senyawa saponin, triterpenoid, dan flavonoid yang berkhasiat sebagai antibakteri. Tujuan dari penelitian ini adalah untuk mengetahui apakah ekstrak etanol buah belimbing wuluh (Averrhoa bilimbi L.) konsentrasi 1% dan 3% dapat diformulasikan sebagai sediaan gel hand sanitizer dan bagaimana stabilitas gel hand sanitizer tersebut. Uji stabilitas sediaan gel hand sanitizer dilakukan dengan metode cycling test, yaitu sediaan gel disimpan pada suhu 4 selama 24 jam, kemudian dipindahkan pada suhu 40 selama 24 jam (1 siklus). Penelitian ini dilakukan selama 6 siklus (12 hari) dengan parameter pengujian organoleptik, homogenitas, pH, daya sebar, viskositas dan sifat alir. Selain itu dilakukan uji syneresis. Hasil penelitian menunjukkan bahwa basis, formula 1 dan 2 memiliki warna yang stabil dan homogen. Basis memiliki pH berkisar 7,22-7,65, formula 1 berkisar 6,87-7,09 dan formula 2 berkisar 5,64-6,18. Basis memiliki daya sebar berkisar 5,03 cm- 5,42 cm , formula 1 berkisar 5,28 cm–6,86 cm dan formula 2 berkisar 5,86 cm-7,60 cm. Viskositas pada basis berkisar 2900 poise–5800 poise, formula 1 berkisar 1260 poise – 1900 poise dan formula 2 berkisar 315 poise–580 poise. Sifat alir gel hand sanitizer mengikuti aliran tiksotropik dan antitiksotropik. Basis mengalami syneresis sebesar 4,694%, formula 1 sebesar 0,568% dan formula 2 sebesar 3,992%. Ekstrak etanol buah belimbing wuluh (Averrhoa bilimbi L.) konsentrasi 1% dan 3% dapat diformulasikan dalam sediaan gel hand sanitizer namun tidak stabil.

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